Elective Neck Dissection Cost-Effective in Oral Cavity Cancer

This article originally appeared here.
Share this content:
Elective Neck Dissection Cost-Effective in Oral Cavity Cancer
Elective Neck Dissection Cost-Effective in Oral Cavity Cancer

TUESDAY, Aug. 23, 2016 (HealthDay News) -- For patients with clinically node-negative oral cavity squamous cell carcinoma, the addition of elective neck dissection to primary surgery is associated with a reduction in overall costs, according to a study published online Aug. 22 in the Journal of Clinical Oncology.

Joseph R. Acevedo, from the University of California in San Diego, and colleagues simulated primary, adjuvant, and salvage therapy; disease recurrence; and survival among patients with T1/T2 clinically node-negative oral cavity squamous cell carcinoma in a Markov model.

In the base-case model, the researchers found that, compared with primary surgery alone, the addition of elective neck dissection to primary surgery reduced overall costs by $6,000 and improved effectiveness by 0.42 quality-adjusted life-years (QALYs) over a lifetime. Less use of salvage therapy caused the decrease in overall cost despite the added neck dissection. The model was most sensitive to assumptions regarding disease recurrence, survival, and health utility reduction from a neck dissection, on one-way sensitivity analysis. At a willingness-to-pay threshold of $100,000/QALY, treatment with elective neck dissection was cost effective 76 percent of the time, in probabilistic sensitivity analysis.

"Our study found that the addition of elective neck dissection reduces costs and improves health outcomes, making this a cost-effective treatment strategy for patients with early-stage oral cavity cancer," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »