Effect of Statins on Alzheimer's May Depend on Gender, Race

Share this content:
Effect of Statins on Alzheimer's May Depend on Gender, Race
Effect of Statins on Alzheimer's May Depend on Gender, Race

MONDAY, Dec. 12, 2016 (HealthDay News) -- Effectiveness of statin use in Alzheimer's prevention may depend on the specific statin, and the gender and race or ethnicity of the patient, according to a study published online Dec. 12 in JAMA Neurology.

Julie Zissimopoulos, Ph.D., of the Schaeffer Center for Health Policy and Economics at the University of Southern California in Los Angeles, and colleagues tracked 399,979 statin users, all aged 65 or older, who took the medications between 2006 and 2013.

Overall, the researchers linked high use of statins to a 15 percent lower risk of Alzheimer's in women and a 12 percent lower risk in men compared to those who had low use. Those who took simvastatin had 10 to 23 percent lower risk, depending on their gender and race. However, the researchers saw no benefit for black men. Among those who used atorvastatin the most, white men and black men had no apparent benefit, while the risk of Alzheimer's was 16 to 39 percent lower for white women, black women, and Hispanics. Only white women appeared to gain a benefit from high usage of pravastatin and rosuvastatin: They had about an 18 percent lower risk of developing Alzheimer's disease.

"The reduction in Alzheimer's disease risk varied across statin molecules, sex, and race/ethnicity. Clinical trials that include racial and ethnic groups need to confirm these findings," the authors write. "Because statins may affect Alzheimer's disease risk, physicians should consider which statin is prescribed to each patient."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Warns Against Children Taking Codeine, Tramadol

FDA Warns Against Children Taking Codeine, Tramadol

Agency strengthens warning labels on these medications to address dangers

Trump Administration Offers Grants to Fight Opioid Crisis

Trump Administration Offers Grants to Fight Opioid Crisis

Money to be used to train health professionals, foster prescription drug monitoring programs

NYC to Raise Cigarette Prices to Highest in the United States

NYC to Raise Cigarette Prices to Highest in ...

Price of pack to jump from $10.50 to $13.00

is free, fast, and customized just for you!

Already a member?

Sign In Now »