ECG Metrics May Predict Cardiac Deaths in CKD Patients

This article originally appeared here.
Share this content:
ECG Metrics May Predict Cardiac Deaths in CKD Patients
ECG Metrics May Predict Cardiac Deaths in CKD Patients

FRIDAY, July 10, 2015 (HealthDay News) -- Certain electrocardiographic (ECG) measures may improve prediction of cardiovascular death in patients with chronic kidney disease (CKD), according to research published online July 9 in the Journal of the American Society of Nephrology.

Rajat Deo, M.D., of the University of Pennsylvania in Philadelphia, and colleagues analyzed data for a prospective cohort of 3,939 participants with CKD to assess whether common ECG parameters are independent predictors of mortality risk.

The researchers found that ECG metrics were independent markers for risk of cardiovascular death, including PR interval ≥200 ms (hazard ratio [HR], 1.62; 95 percent confidence interval [CI], 1.19 to 2.19); QRS interval 100 to 119 ms (HR, 1.64; 95 percent CI, 1.20 to 2.25) and ≥120 ms (HR, 1.75; 95 percent CI, 1.17 to 2.62); corrected QT interval ≥450 ms in men or ≥460 ms in women (HR, 1.72; 95 percent CI, 1.19 to 2.49); and heart rate ≥90 beats per minute (HR, 2.35; 95 percent CI, 1.03 to 5.33). Most ECG metrics were stronger markers of risk for cardiovascular death than for noncardiovascular death or all-cause mortality. Adding these markers to a comprehensive model of cardiorenal risk factors significantly increased the C-statistic for cardiovascular death from 0.77 to 0.81.

"These data suggest common ECG metrics are independent risk factors for cardiovascular death and enhance the ability to predict death events in a population with CKD," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists can suggest adjustments for meds taken several times per day, those affected by food intake

AUA: Many Have Unused Opioids After Urologic Procedures

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Over Half of Young Adult Smoke Volume Exposure From Hookahs

Over Half of Young Adult Smoke Volume Exposure ...

Toxicant exposure to tar, carbon monoxide, nicotine lower, but still substantial, compared to cigarettes

is free, fast, and customized just for you!

Already a member?

Sign In Now »