Duration of Diabetes, Prediabetes Linked to Presence of CAC

Share this content:
Duration of Diabetes, Prediabetes Linked to Presence of CAC
Duration of Diabetes, Prediabetes Linked to Presence of CAC

FRIDAY, Jan. 12, 2018 (HealthDay News) -- Diabetes and prediabetes duration are both independently associated with the presence of coronary artery calcified plaque (CAC) and left ventricular dysfunction, according to a study published online Jan. 9 in Diabetes Care.

Jared P. Reis, Ph.D., from the National Heart, Lung, and Blood Institute in Bethesda, Md., and colleagues examined whether the durations of diabetes and prediabetes estimated during a 25-year period in early adulthood are independently associated with CAC. Data were included for 3,628 white and black adults aged 18 to 30 years without diabetes or prediabetes at baseline (1985 to 1986).

The researchers found that 12.7 and 53.8 percent of the participants developed diabetes and prediabetes, respectively, with an average duration of 10.7 and 9.5 years. The hazard ratio for the presence of CAC was 1.15 and 1.07 times higher for each five-years-longer duration of diabetes and prediabetes, respectively, after adjustment for sociodemographic characteristics and other cardiovascular risk factors and mutual adjustment for each other. There was a correlation for diabetes and prediabetes duration with worse subclinical systolic function and early diastolic relaxation. There was also a correlation for duration of diabetes with higher diastolic filling pressure.

"Durations of diabetes and prediabetes during adulthood are both independently associated with subclinical atherosclerosis and left ventricular systolic and diastolic dysfunction in middle age," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters


More in Home

FDA Approves First Drug for Rare Form of Rickets

FDA Approves First Drug for Rare Form of ...

Crysvita approved for adults and children ages 1 year and older with x-linked hypophosphatemia

High FGF-23 Linked to Recurrent Cardiac Events After ACS

High FGF-23 Linked to Recurrent Cardiac Events After ...

FGF-23 in top quartile independently linked to greater risk of CV death, heart failure hospitalization

Medical Cannabis Not Recommended for Sleep Apnea

Medical Cannabis Not Recommended for Sleep Apnea

American Academy of Sleep Medicine says evidence insufficient to recommend cannabis for apnea

is free, fast, and customized just for you!

Already a member?

Sign In Now »