Dry Mouth Common Medication Reaction in Older Adults

Share this content:
Dry Mouth Common Medication Reaction in Older Adults
Dry Mouth Common Medication Reaction in Older Adults

WEDNESDAY, Nov. 1, 2017 (HealthDay News) -- In older adults, medication use is significantly associated with xerostomia and salivary gland dysfunction, according to a review published online Oct. 26 in the Journal of the American Geriatrics Society.

Edwin C.K. Tan, Ph.D., from Monash University in Australia, and colleagues conducted a systematic literature review (1990 to 2016) to identify older people (aged ≥60) who participated in intervention or observational studies investigating drug use as an exposure and xerostomia or salivary gland hypofunction as adverse drug outcomes. There were 52 eligible studies, 26 of which were included in meta-analysis.

The researchers found that urological medications (odds ratio [OR], 5.91), antidepressants (OR, 4.74), and psycholeptics (OR, 2.59) were significantly associated with dry mouth in intervention studies. In the observational studies, several medication classes, as well as numbers of medications taken, were significantly associated with xerostomia and salivary gland hypofunction. Overall, the majority of studies were rated as having moderate methodological quality.

"Future research should develop a risk score for medication-induced dry mouth to assist with prescribing and medication management," conclude the authors.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

High Costs Associated With Physician Burnout, Attrition

High Costs Associated With Physician Burnout, Attrition

Economic loss at Stanford over two years expected to range from $15.5 million to $55.5 million

Insulin Doesn't Prevent Diabetes in Relatives of T1DM Patients

Insulin Doesn't Prevent Diabetes in Relatives of T1DM ...

Oral insulin doesn't delay onset in autoantibody-positive relatives of patients with type 1 diabetes

Workplace Sexual Harassment Ongoing in Women, Up for Men

Workplace Sexual Harassment Ongoing in Women, Up for ...

Women report more adverse effects after SH than men, but SH can trigger depression, anxiety in men

is free, fast, and customized just for you!

Already a member?

Sign In Now »