Drug-Eluting Contact Lenses May Help Treat Glaucoma

This article originally appeared here.
Share this content:
Drug-Eluting Contact Lenses May Help Treat Glaucoma
Drug-Eluting Contact Lenses May Help Treat Glaucoma

TUESDAY, Aug. 30, 2016 (HealthDay News) -- Latanoprost-eluting contact lenses are effective at lowering intraocular pressure in a glaucoma model, according to an experimental study published online Aug. 29 in Ophthalmology.

Joseph Ciolino, M.D., an ophthalmologist at Massachusetts Eye and Ear and an assistant professor of ophthalmology at Harvard Medical School in Boston, and colleagues tested the effectiveness of latanoprost-eluting low-dose contact lenses (CLLO) in four monkeys with glaucoma. The drug-administering contact lenses have a medicated polymer film that slowly delivered latanoprost to the monkeys' eyes.

The team found that the CLLO reduced intraocular pressure as much as the daily ophthalmic solution version of the medication. And lenses that dispensed higher doses of the drug resulted in greater reduction of intraocular pressure than the eye drops.

"Instead of taking a contact lens and allowing it to absorb a drug and release it quickly, our lens uses a polymer film to house the drug, and the film has a large ratio of surface area to volume, allowing the drug to release more slowly," senior author Daniel Kohane, M.D., Ph.D., director of the Laboratory for Biomaterials and Drug Delivery at Boston Children's Hospital, said in a news release from the Massachusetts Eye and Ear Infirmary.

Two authors are named as inventors on a patent for the drug-eluting contact lens evaluated in this study.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

ASTRO: No Survival Benefit for Adding EBT to Brachytherapy

ASTRO: No Survival Benefit for Adding EBT to ...

Addition of external beam therapy doesn't improve five-year progression-free survival in prostate cancer

ASTRO: Fewer Side Effects With IMRT in Cervical, Endometrial CA

ASTRO: Fewer Side Effects With IMRT in Cervical, ...

Patients in conventional radiotherapy arm had more high-level adverse events than those in IMRT arm

Many Doctors Reluctant to Reveal Mental Health Issues

Many Doctors Reluctant to Reveal Mental Health Issues

Perceived stigma, fear of career repercussions hinder treatment, study suggests

is free, fast, and customized just for you!

Already a member?

Sign In Now »