Drug-Eluting Contact Lenses May Help Treat Glaucoma

This article originally appeared here.
Share this content:
Drug-Eluting Contact Lenses May Help Treat Glaucoma
Drug-Eluting Contact Lenses May Help Treat Glaucoma

TUESDAY, Aug. 30, 2016 (HealthDay News) -- Latanoprost-eluting contact lenses are effective at lowering intraocular pressure in a glaucoma model, according to an experimental study published online Aug. 29 in Ophthalmology.

Joseph Ciolino, M.D., an ophthalmologist at Massachusetts Eye and Ear and an assistant professor of ophthalmology at Harvard Medical School in Boston, and colleagues tested the effectiveness of latanoprost-eluting low-dose contact lenses (CLLO) in four monkeys with glaucoma. The drug-administering contact lenses have a medicated polymer film that slowly delivered latanoprost to the monkeys' eyes.

The team found that the CLLO reduced intraocular pressure as much as the daily ophthalmic solution version of the medication. And lenses that dispensed higher doses of the drug resulted in greater reduction of intraocular pressure than the eye drops.

"Instead of taking a contact lens and allowing it to absorb a drug and release it quickly, our lens uses a polymer film to house the drug, and the film has a large ratio of surface area to volume, allowing the drug to release more slowly," senior author Daniel Kohane, M.D., Ph.D., director of the Laboratory for Biomaterials and Drug Delivery at Boston Children's Hospital, said in a news release from the Massachusetts Eye and Ear Infirmary.

Two authors are named as inventors on a patent for the drug-eluting contact lens evaluated in this study.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ASH: Synthetic Blood Cell Passes Proof-of-Concept Testing

ASH: Synthetic Blood Cell Passes Proof-of-Concept Testing

Synthetic product made from purified human hemoglobin proteins coated with a synthetic polymer

Fewer School Shootings in States With Tighter Gun Laws

Fewer School Shootings in States With Tighter Gun ...

Study also found that states that spent more money on mental health care, education saw less violence

SABCS: No Survival Benefit Seen for Letrozole Beyond Five Years

SABCS: No Survival Benefit Seen for Letrozole Beyond ...

Study found women who continued with letrozole did experience other benefits, however

is free, fast, and customized just for you!

Already a member?

Sign In Now »