DNA Tests May Aid Diagnosis of CNS Infections

This article originally appeared here.
Share this content:
DNA Tests May Aid Diagnosis of CNS Infections
DNA Tests May Aid Diagnosis of CNS Infections

FRIDAY, June 24, 2016 (HealthDay News) -- Genetic testing may help diagnose or rule out central nervous system (CNS) infections, according to research published online June 13 in Neurology: Neuroimmunology & Neuroinflammation.

The study included 10 patients, aged 16 to 68, with signs of CNS infection, including fever, weakness in limbs, partial paralysis, numbness, headache, or seizures. The researchers took brain or spinal cord biopsies and sequenced the DNA in the tissue. They looked for evidence of bacteria, viruses, and other pathogens that could cause infection.

"By incorporating modern genetic sequencing techniques into pathology diagnostics, we were able to investigate the potential presence of infection in 10 subjects and found appropriate explanations of clinical problems in eight out of 10 patient cases examined in this study," study author Carlos Pardo-Villamizar, M.D., an associate professor of neurology at Johns Hopkins University in Baltimore, said in a university news release.

"We hope to develop this technique further as a way to bring the diagnosis rate of inflammatory brain disorders and infections closer to 100 percent so we can treat patients more effectively," Pardo-Villamizar added.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

High Costs Associated With Physician Burnout, Attrition

High Costs Associated With Physician Burnout, Attrition

Economic loss at Stanford over two years expected to range from $15.5 million to $55.5 million

Insulin Doesn't Prevent Diabetes in Relatives of T1DM Patients

Insulin Doesn't Prevent Diabetes in Relatives of T1DM ...

Oral insulin doesn't delay onset in autoantibody-positive relatives of patients with type 1 diabetes

Workplace Sexual Harassment Ongoing in Women, Up for Men

Workplace Sexual Harassment Ongoing in Women, Up for ...

Women report more adverse effects after SH than men, but SH can trigger depression, anxiety in men

is free, fast, and customized just for you!

Already a member?

Sign In Now »