Diagnostic Yield of Brugada Syndrome Up With Modified Leads

This article originally appeared here.
Share this content:
Diagnostic Yield of Brugada Syndrome Up With Modified Leads
Diagnostic Yield of Brugada Syndrome Up With Modified Leads

FRIDAY, April 29, 2016 (HealthDay News) -- Use of V1 and V2 leads recorded in the second and third intercostal spaces (High-ICS) increases the diagnostic yield for Brugada syndrome (BrS), according to a study published online April 21 in the Journal of Cardiovascular Electrophysiology.

Antonio Curcio, M.D., Ph.D., from the Magna Graecia University in Catanzaro, Italy, and colleagues identified 300 subjects from a Brugada syndrome registry, without a diagnostic coved ST-segment elevation in conventional V1 to V3 leads. They examined the clinical presentation and arrhythmic risk in this subgroup of patients discovered only with modified leads.

The researchers found that 21.3 percent of the patients (64 patients) were diagnosed with High-ICS. Four of the patients were diagnosed at baseline, while 60 were diagnosed after drug-challenge with sodium-channel blockers. Overall, 4.7 percent of patients with spontaneous abnormal electrocardiogram experienced cardiac events, with an annual event rate of 0.11 percent, which was similar to that of the low-risk BrS category diagnosed in standard leads.

"This study demonstrates that the use of new diagnostic criteria for BrS allows increasing the diagnostic yield by 20 percent and that the arrhythmic risk is low when BrS can be established only in High-ICS," the authors write. "We also show that the prognostic value of spontaneous electrocardiogram pattern is confirmed in this subgroup."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Dermatography Helps Lessen Appearance of Surgical Scars

Dermatography Helps Lessen Appearance of Surgical Scars

Pigments can restore more natural skin appearance that patients are happy with

Drug-Resistant Bacteria Live in America's Water Systems

Drug-Resistant Bacteria Live in America's Water Systems

Bacteria found in plumbing may sicken thousands each year

Deep Brain Stimulation May Improve TBI Symptoms

Deep Brain Stimulation May Improve TBI Symptoms

Deep brain stimulation appears to boost function and quality of life

is free, fast, and customized just for you!

Already a member?

Sign In Now »