Depressive Symptoms Linked to Reduced Fecundability

This article originally appeared here.
Share this content:
Depressive Symptoms Linked to Reduced Fecundability
Depressive Symptoms Linked to Reduced Fecundability

FRIDAY, June 3, 2016 (HealthDay News) -- Depressive symptoms are associated with reduced fecundability, according to a study published online April 28 in the American Journal of Obstetrics and Gynecology.

Yael I. Nillni, Ph.D., from the Veterans Affairs Boston Healthcare System, and colleagues derived data from Pregnancy Study Online, an internet-based preconception cohort study of couples attempting to conceive. Female participants completed a survey at baseline and every eight weeks for up to 12 months or reported conception. Data were included for 2,146 women who had been trying to conceive for no more than six cycles at study entry.

The researchers found that, compared with no or low depressive symptoms, severe depressive symptoms at baseline correlated with decreased fecundability, regardless of treatment (fecundability ratio, 0.62; 95 percent confidence interval [CI], 0.43 to 0.91). For a 10-U increase in Major Depression Inventory score, the fecundability ratio was 0.90 (95 percent CI, 0.83 to 0.97). Compared to women who had no/mild depressive symptoms and had never used psychotropic medication, reduced fecundability was seen for women who reported moderate to severe symptoms and had never received psychotropic medications or who were currently being treated with psychotropic medications (fecundability ratios, 0.69 [95 percent CI, 0.48 to 0.99] and 0.72 [95 percent CI, 0.44 to 1.20], respectively). Regardless of depressive symptoms, formers users of psychotropic medications had increased fecundability (fecundability ratios, 1.22 [95 percent CI, 1.06 to 1.39] for no/mild symptoms and 1.18 [95 percent CI, 0.80 to 1.76] for moderate to severe symptoms).

"We found an inverse association between depressive symptoms and fecundability, independent of psychotropic medication use," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ASA: Male Stroke Patients Twice As Likely to Get Timely tPA

ASA: Male Stroke Patients Twice As Likely to ...

Researchers not sure why the disparity exists

CDC: Fatal Drug Overdoses More Than Doubled Since 1999

CDC: Fatal Drug Overdoses More Than Doubled Since ...

Whites, middle-aged adults hardest hit, researchers find

Rates of Resistant Infections Up in U.S. Children

Rates of Resistant Infections Up in U.S. Children

Research highlights increasing community vulnerability

is free, fast, and customized just for you!

Already a member?

Sign In Now »