Depressive Symptoms Linked to Functional Status in CAD

Share this content:
Depressive Symptoms Linked to Functional Status in CAD
Depressive Symptoms Linked to Functional Status in CAD

MONDAY, Oct. 31, 2016 (HealthDay News) -- For patients with stable coronary artery disease, depressive symptoms and cardiac disease severity independently affect patient-reported functional status, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

David W. Schopfer, M.D., from the University of California in San Francisco, and colleagues compared the associations of depressive symptoms and objective measures of cardiac disease severity with perceived functional status in 1,023 patients with stable coronary artery disease. The extent to which patient-reported functional status was influenced by depressive symptoms was assessed. Perceived functional status was then evaluated as a predictor of subsequent cardiovascular hospitalizations during 8.8 years of follow-up.

The researchers found that, compared to patients without depressive symptoms, those with depressive symptoms were more likely to report poor functional status (44 versus 17 percent; P < 0.001). Independent predictors of poor functional status were depressive symptoms, poor exercise capacity, and history of heart failure, after adjustment for traditional risk factors and comorbid conditions (odds ratios, 2.68, 2.30, and 1.61, respectively). After adjustment for confounding variables, compared with patients who had class I functional status, those with class II and class III or IV functional status had an increased rate of hospitalization for heart failure (hazard ratios, 1.96 and 2.04, respectively).

"Perceived functional status may be as strongly influenced by depressive symptoms as it is by cardiovascular disease severity," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Caffeine Found to Reduce Age-Related Inflammation

Caffeine Found to Reduce Age-Related Inflammation

Connection between advancing age, systemic inflammation, cardiovascular disease and caffeine

Neonatal Abstinence Syndrome Tied to Poor School Performance

Neonatal Abstinence Syndrome Tied to Poor School Performance

By seventh grade, four out of 10 failed to meet standards in at least one academic area

Heart Rate Variability Linked to Atrial Fibrillation

Heart Rate Variability Linked to Atrial Fibrillation

Lower HRV, increased sympathetic/parasympathetic tone linked to higher risk of a-fib

is free, fast, and customized just for you!

Already a member?

Sign In Now »