Deep Brain Stimulation Appears Safe in Patients With Alzheimer's

Share this content:
Deep Brain Stimulation Appears Safe in Patients With Alzheimer's
Deep Brain Stimulation Appears Safe in Patients With Alzheimer's

THURSDAY, July 28, 2016 (HealthDay News) -- Deep brain stimulation (DBS) appears safe for patients with early Alzheimer's disease (AD) -- and might even slow down memory loss in some, according to a preliminary study published online July 18 in the Journal of Alzheimer's Disease.

Andres Lozano, M.D., Ph.D., a neurosurgeon at Toronto Western Hospital, and colleagues implanted DBS systems in 42 patients with mild Alzheimer's symptoms, 12 of whom were younger than 65. The system was activated in only half of the patients, with the other half serving as control. The system was programmed to stimulate the fornix.

Over one year, the researchers found, the treatment appeared relatively safe. In patients whose DBS system was turned on, cerebral glucose metabolism in key brain areas increased over the first six months, although this was no longer apparent after one year. For patients younger than 65, cognitive function worsened when the DBS system was turned on; for older patients, the treatment seemed to slow down their decline over one year.

"DBS for AD was safe and associated with increased cerebral glucose metabolism," the authors write. "There were no differences in cognitive outcomes for participants as a whole, but participants aged ≥65 years may have derived benefit while there was possible worsening in patients below age 65 years with stimulation."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Recent Decline in Prescription Opioid Use Among U.S. Teens

Recent Decline in Prescription Opioid Use Among U.S. ...

Lifetime prevalence of use peaked in 1989, 2002, and remained stable until decline in 2013 to 2015

Treatment Seeking Low Among Teens With Eating Disorders

Treatment Seeking Low Among Teens With Eating Disorders

Those with counter-stereotypic presentation even less likely to seek treatment

Optical Clearing Agent Ups No. of Laser Passes in Tattoo Removal

Optical Clearing Agent Ups No. of Laser Passes ...

Findings based on number of laser passes during a five-minute tattoo removal session

is free, fast, and customized just for you!

Already a member?

Sign In Now »