December 2016 Briefing - Pediatrics

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Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for December 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Ledipasvir-Sofosbuvir Effective for Chronic HCV in Adolescents

FRIDAY, Dec. 30, 2016 (HealthDay News) -- For adolescents with chronic hepatitis C virus (HCV) genotype 1 infection, ledipasvir-sofosbuvir is highly effective, according to a study published online Dec. 20 in Hepatology.

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Racial Disparity Seen in Mortality for Peds End-Stage Renal Disease

FRIDAY, Dec. 30, 2016 (HealthDay News) -- For children with end-stage renal disease starting renal replacement therapy (RRT) there is racial disparity in the risk of death, according to a study published online Dec. 29 in the Journal of the American Society of Nephrology.

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Survey Shows Lower Rate of Impaired Driving in U.S. for 2014

THURSDAY, Dec. 29, 2016 (HealthDay News) -- The prevalence of driving under the influence of alcohol and illicit drugs has been quantified in a report published Dec. 28 by the Substance Abuse and Mental Health Services Administration.

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Selumetinib Active in Children With Neurofibromatosis Type 1

THURSDAY, Dec. 29, 2016 (HealthDay News) -- The oral selective inhibitor of MAPK kinase 1 and 2, selumetinib, is active in children with neurofibromatosis type 1 and inoperable plexiform neurofibromas, according to a study published in the Dec. 29 issue of the New England Journal of Medicine.

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Fish-Oil Fatty Acids in Pregnancy Cut Wheeze, Asthma Risk in Child

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- For women in the third trimester of pregnancy, supplementation with n-3 long-chain polyunsaturated fatty acids (LCPUFAs) is associated with a reduction in the risk of persistent wheeze and asthma in offspring, according to a study published in the Dec. 29 issue of the New England Journal of Medicine.

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Ciprofloxacin Plus Fluocinolone More Effective for Peds AOMT

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- For children with acute otitis media with tympanostomy tubes (AOMT), ciprofloxacin plus fluocinolone is more effective than ciprofloxacin or fluocinolone alone, according to a study published online Dec. 22 in JAMA Otolaryngology-Head & Neck Surgery.

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Case Report: Ustekinumab for Crohn's Continued in Pregnancy

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- Good outcome has been reported in a pregnant woman who continued ustekinumab (UST) therapy for Crohn's disease during pregnancy, according to a case report published online Dec. 22 in the Journal of Clinical Pharmacy and Therapeutics.

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Bell's Palsy Tied to Quadrivalent Meningococcal Vaccine

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- Bell's palsy is the only prespecified adverse event associated with the MenACWY-CRM quadrivalent meningococcal conjugate vaccine, according to a study published online Dec. 26 in Pediatrics.

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1996-2013 Saw Increase in U.S. Health Care Spending on Children

TUESDAY, Dec. 27, 2016 (HealthDay News) -- Health care spending on children increased from 1996 to 2013 in the United States, according to a study published online Dec. 27 in JAMA Pediatrics.

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Legalization of Marijuana May Impact Teen Perception, Use

TUESDAY, Dec. 27, 2016 (HealthDay News) -- Following legalization of marijuana use, perceived harmfulness of marijuana use decreased and marijuana use increased among eighth and 10th graders in Washington State, according to a study published online Dec. 27 in JAMA Pediatrics.

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Families Provide 1.5B Hours of Care to Special Needs Children

TUESDAY, Dec. 27, 2016 (HealthDay News) -- Children with special health care needs (CSHCN) receive 1.5 billion hours of health care at home from family members, according to a study published online Dec. 27 in Pediatrics.

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Personal Health Care Spending Continues to Soar in the U.S.

TUESDAY, Dec. 27, 2016 (HealthDay News) -- From 1996 to 2013 there were considerable increases in personal health care spending in the United States, with the highest amounts for diabetes, ischemic heart disease, and low back and neck pain, according to a study published in the Dec. 27 issue of the Journal of the American Medical Association.

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Shortened Abx Inferior for Acute Otitis Media in Children <2 Years

THURSDAY, Dec. 22, 2016 (HealthDay News) -- Reduced-duration antimicrobial treatment is associated with less favorable outcomes among infants with acute otitis media, according to a study published in the Dec. 22 issue of the New England Journal of Medicine.

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Antiseptics Not Needed for Cord Care in Developed Nations

THURSDAY, Dec. 22, 2016 (HealthDay News) -- Dry cord care is noninferior to the use of antiseptics in preventing omphalitis in full-term newborns in France, according to a study published online Dec. 22 in Pediatrics.

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ACOG Recommends Delayed Umbilical Cord Clamping

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- Delayed umbilical cord clamping is beneficial for most term and preterm infants, according to a Committee Opinion from the American College of Obstetrics and Gynecology (ACOG) published in the January issue of Obstetrics & Gynecology.

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24/7 Intensivist in Pediatric ICU Improves Patient Outcomes

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- Having a 24/7 intensivist in pediatric intensive care units (ICUs) is associated with improved patient outcomes, according to a study published in the Dec. 15 issue of the American Journal of Respiratory and Critical Care Medicine.

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Risk of Postconcussive Symptoms Down With Early Exercise

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Participation in physical activity within seven days after injury is associated with reduced rates of persistent postconcussive symptoms (PPCS), according to a study published in the Dec. 20 issue of the Journal of the American Medical Association.

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Health Care Provider Burnout Negatively Affects Quality, Safety

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Health care provider burnout is negatively associated with quality and safety of health care, according to a meta-analysis published recently in the Journal of General Internal Medicine.

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Guidance on Dietary Sugar Intake Based on Low-Quality Evidence

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Guidelines on dietary sugar intake are of poor quality, and the supporting evidence is of low quality, according to research published online Dec. 20 in the Annals of Internal Medicine.

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Therapeutic Hypothermia Benefits Adults With TBI

TUESDAY, Dec. 20, 2016 (HealthDay News) -- For adults, but not children, with traumatic brain injuries, therapeutic hypothermia is beneficial, according to a meta-analysis published online Dec. 9 in Critical Care Medicine.

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DEA Announces Critical Changes in Registration Renewal Process

MONDAY, Dec. 19, 2016 (HealthDay News) -- The Drug Enforcement Administration (DEA) has announced critical changes in its registration renewal process, according to a report published by the American Academy of Family Physicians.

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Twitter Chatter About HPV Vaccine Mostly Positive

MONDAY, Dec. 19, 2016 (HealthDay News) -- Twitter conversations regarding the human papillomavirus (HPV) vaccine tend to be positive, according to a study published online Dec. 5 in the Journal of Medical Internet Research.

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AAP Issues New Guidelines for Use of Human Donor Milk

MONDAY, Dec. 19, 2016 (HealthDay News) -- Use of donor milk is safe when appropriate measures are used to screen donors and collect, store, and pasteurize the milk, according to a policy statement from the American Academy of Pediatrics published online Dec. 19 in Pediatrics.

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Review Provides Evidence for Sweet Taste Analgesia in Infants

FRIDAY, Dec. 16, 2016 (HealthDay News) -- Despite evidence for sweet taste reducing pain and crying time in neonates, most trials still include placebo/no-treatment arms, according to a review published online Dec. 16 in Pediatrics.

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No Long-Term Increase in Exercise Levels for Pokémon Go

FRIDAY, Dec. 16, 2016 (HealthDay News) -- Pokémon Go provided a slight, short-term boost to adults' physical activity levels, but it didn't last, according to a study published in the Christmas issue of The BMJ.

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MRI Ups Diagnostic Accuracy of Fetal Brain Abnormalities

FRIDAY, Dec. 16, 2016 (HealthDay News) -- Follow-up magnetic resonance imaging (MRI) after a mid-pregnancy ultrasound could help improve diagnosis of possible fetal brain abnormalities, according to a study published online Dec. 14 in The Lancet.

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Home-Visiting Program Can Reduce Infant Health Care Use

THURSDAY, Dec. 15, 2016 (HealthDay News) -- A universal home visiting model that employs a nurse-parent educator team as visitors in the homes of primary caregivers and their first-born children can reduce health care use in the first year, according to a study published online Dec. 15 in Pediatrics.

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SIOP Scale Best for Detecting Ototoxicity With Cisplatin Tx

THURSDAY, Dec. 15, 2016 (HealthDay News) -- The Society for Industrial and Organizational Psychology Ototoxicity Scale (SIOP) seems to be best for classifying ototoxicity in cisplatin-treated pediatric patients, according to a study published online Dec. 12 in the Journal of Clinical Oncology.

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FDA Issues New Safety Info on Use of Anesthesia

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Repeated or lengthy use -- longer than three hours -- of general anesthetic and sedation drugs may harm the developing brains of fetuses and children younger than 3 years old, the U.S. Food and Drug Administration warned Wednesday.

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Screening, Treatment of ROP Varies Across NICUs

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Variation exists across neonatal intensive care units (NICUs) regarding implementation of screening and treatment of retinopathy of prematurity (ROP), according to research published online Dec. 14 in Pediatrics.

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Zika-Related Birth Defects More Extensive Than Thought

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Zika's ability to damage the infant brain may be even more far-reaching and insidious than previously thought, two new studies suggest.

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Under-Reporting of Child Abuse Suspected Within U.S. Army

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- Child abuse within U.S. Army families may be significantly under-reported, according to a study published online Dec. 12 in Child Abuse & Neglect.

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Exposure to Mold, Dampness Ups Risk of Asthma, Rhinitis

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- Exposure to mold and dampness during infancy is associated with increased risk of asthma and rhinitis up to age 16 years, according to a study published online Dec. 7 in Allergy.

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NIH: Teen Drug Use Continuing to Decline

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Illicit drug use among U.S. teens is at an all-time low, with the exception of marijuana, according to a new survey by the U.S. National Institute on Drug Abuse.

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Neonatal Abstinence Syndrome Up in Rural-Born Infants

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Rural U.S. communities are seeing a sharp increase in infants with neonatal abstinence syndrome (NAS), according to a research letter published online Dec. 12 in JAMA Pediatrics.

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Prenatal Exposure to Maternal Stress May Raise Psoriasis Risk

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Prenatal exposure to maternal bereavement is associated with psoriasis only for children born to a mother who lost a partner/spouse or an older child, according to a study published online Dec. 7 in the British Journal of Dermatology.

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Recommendations Developed for Pediatric NAFLD

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Evidence-based recommendations have been developed for screening, diagnosis, and treatment of pediatric nonalcoholic fatty liver disease (NAFLD). The guidelines were published online Nov. 30 in the Journal of Pediatric Gastroenterology and Nutrition.

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CDC: U.S. Flu Vaccination Rates Low So Far This Season

MONDAY, Dec. 12, 2016 (HealthDay News) -- Only about two out of five Americans had gotten this season's flu vaccination as of early November, the U.S. Centers for Disease Control and Prevention reports.

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Continuous Skin-to-Skin Contact Benefits Preemies Long Term

MONDAY, Dec. 12, 2016 (HealthDay News) -- "Kangaroo mother care" -- an intense version of care involving nearly round-the-clock skin-to-skin contact and exclusive or near-exclusive breastfeeding -- may extend and enhance the lives of premature and low birth weight infants well into adulthood, according to a study published online Dec. 12 in Pediatrics.

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Clinical Antecedents of Adolescent-Onset MDD Identified

MONDAY, Dec. 12, 2016 (HealthDay News) -- Irritability and fear and/or anxiety are significant clinical antecedents of new adolescent-onset major depressive disorder (MDD) in individuals at familial risk, according to a study published online Dec. 7 in JAMA Psychiatry.

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CDC: Colombia Sees Increase in Zika-Related Microcephaly

MONDAY, Dec. 12, 2016 (HealthDay News) -- Colombia is now experiencing a sharp increase in cases of infant microcephaly, according to research published in the Dec. 9 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Anesthesiologist Reaction Time Increased After Night Call

MONDAY, Dec. 12, 2016 (HealthDay News) -- For anesthesiologists, reaction time increases after a night call, with greater increases seen in correlation with reliance on avoidance as a coping mechanism, according to a study published online Nov. 30 in Pediatric Anesthesia.

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Nusinersen Shows Promise in Spinal Muscular Atrophy

THURSDAY, Dec. 8, 2016 (HealthDay News) -- An experimental drug for infants with spinal muscular atrophy type 1 appears to be effective, according to research published online Dec. 5 in The Lancet.

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Titanium Exposure Tied to Yellow Nail Syndrome in Pediatric Patient

THURSDAY, Dec. 8, 2016 (HealthDay News) -- In a case report published online Dec. 7 in Pediatrics, yellow nail syndrome (YNS) is described in a 9-year-old girl who had titanium detected in her nail clippings.

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Fewer School Shootings in States With Tighter Gun Laws

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- There are fewer school shootings in states that have tighter gun control laws and spend more on mental health care and public education, according to a report published online Dec. 6 in Injury Prevention.

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Learning Interventions Can Improve Med Student Well-Being

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Specific learning interventions may improve emotional well-being among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Number of Cancer Cases, Deaths Up Globally

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Cancer cases rose 33 percent worldwide in the past 10 years, according to a report published online Dec. 3 in JAMA Oncology.

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Prevalence of Disability 2.7 Percent at U.S. Medical Schools

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools, according to a research letter published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue of medical education.

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Depression, Suicide Ideation Prevalent in Medical Students

TUESDAY, Dec. 6, 2016 (HealthDay News) -- The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent, respectively, among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Clinical Practice Guidelines Cut Pediatric Hospitalizations for DKA

TUESDAY, Dec. 6, 2016 (HealthDay News) -- Implementation of clinical practice guidelines can reduce the length of hospitalizations among children experiencing diabetic ketoacidosis (DKA), according to a study published Nov. 29 in the Journal of Evaluation in Clinical Practice.

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Announcement Training Ups HPV Vaccination for Adolescents

MONDAY, Dec. 5, 2016 (HealthDay News) -- Training providers to use announcements can increase human papillomavirus (HPV) vaccination coverage in young adolescents, according to a study published online Dec. 5 in Pediatrics.

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Study Explores Factors Linked to Successful Peanut OFC

MONDAY, Dec. 5, 2016 (HealthDay News) -- Early peanut introduction is associated with increased probability of a successful oral food challenge (OFC), with higher odds for introduction between 6 to 11 versus 4 to 6 months, according to a study published online Nov. 30 in Allergy.

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Psychotherapy for Depression Offers Teens Long-Term Benefits

FRIDAY, Dec. 2, 2016 (HealthDay News) -- For teens with depression, many could reap long-term benefits from psychological counseling, according to a study published online Nov. 30 in The Lancet Psychiatry.

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Ultraviolet B Radiation Exposure Tied to Decreased Risk of Myopia

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Spending more time outside early in life may offer some protection against myopia, according to a study published online Dec. 1 in JAMA Ophthalmology.

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Vitamin D in Pregnancy Might Help Prevent MS in Offspring

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Newborns with low levels of vitamin D may have higher odds of developing multiple sclerosis (MS) later in life, according to a study published online Nov. 30 in Neurology.

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PCPs Order More Food Allergen Panels Than Allergists

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Primary care providers (PCPs) order significantly more food allergen panels and generate higher costs per patient than allergists, according to a review published online Nov. 30 in Pediatrics.

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CDC: Fewer U.S. Families Struggling to Pay Medical Bills

THURSDAY, Dec. 1, 2016 (HealthDay News) -- The number of people in families having problems paying medical bills fell by nearly 13 million from 2011 through the first six months of 2016, according to a report published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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