December 2016 Briefing - OBGYN & Women's Health

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Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for December 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Pharmacy-Based Sale of Chlamydia Test Kits Is Effective

FRIDAY, Dec. 30, 2016 (HealthDay News) -- It is feasible to sell chlamydia test kits through pharmacies and use existing health infrastructure to follow up on results and manage clients, according to a pilot study published online Dec. 23 in the Journal of Pharmacy Practice and Research.

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Fatigue Levels Vary for Patients With Psoriatic Disease

FRIDAY, Dec. 30, 2016 (HealthDay News) -- Patients with psoriatic arthritis have higher levels of fatigue than patients with psoriasis treated with phototherapy or systemic treatment, according to a research letter published online Dec. 22 in the British Journal of Dermatology.

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Panel of 88 SNPs Predicts Breast CA Risk in Women at High Risk

FRIDAY, Dec. 30, 2016 (HealthDay News) -- A panel of 88 single nucleotide polymorphisms (SNPs) can predict breast cancer risk, according to a study published online Dec. 28 in the Journal of Clinical Oncology.

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Female Gender Predictor of All-Cause Mortality After PCI

THURSDAY, Dec. 29, 2016 (HealthDay News) -- Female gender is an independent predictor of all-cause mortality after percutaneous coronary intervention (PCI), according to a study published in the Jan. 15 issue of The American Journal of Cardiology.

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Triple-Negative Breast CA Risk Up for Blacks With Benign Breast Dz

THURSDAY, Dec. 29, 2016 (HealthDay News) -- African-American (AA) identity is associated with increased risk of triple-negative breast cancer (TNBC) among women with a prior diagnosis of benign breast disease (BBD), according to a study published online Dec. 22 in JAMA Oncology.

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Reoperation Risk for Nonpalpable Breast Lesions Higher for DCIS

THURSDAY, Dec. 29, 2016 (HealthDay News) -- For women undergoing wire-guided breast conserving surgery (BCS) for nonpalpable breast lesions, the risk of reoperation is higher for those with ductal carcinoma in situ (DCIS) than those with invasive breast cancer (IBC), according to a study published online Dec. 21 in JAMA Surgery.

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Increase in HPV Prevalence Seen After Renal Transplant in Women

THURSDAY, Dec. 29, 2016 (HealthDay News) -- An increase in human papillomavirus (HPV) prevalence after renal transplantation (RT) may result from reactivation of latent HPV infections in women, according to a study published online Dec. 23 in the American Journal of Transplantation.

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Fish-Oil Fatty Acids in Pregnancy Cut Wheeze, Asthma Risk in Child

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- For women in the third trimester of pregnancy, supplementation with n-3 long-chain polyunsaturated fatty acids (LCPUFAs) is associated with a reduction in the risk of persistent wheeze and asthma in offspring, according to a study published in the Dec. 29 issue of the New England Journal of Medicine.

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Case Report: Ustekinumab for Crohn's Continued in Pregnancy

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- Good outcome has been reported in a pregnant woman who continued ustekinumab (UST) therapy for Crohn's disease during pregnancy, according to a case report published online Dec. 22 in the Journal of Clinical Pharmacy and Therapeutics.

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Personal Health Care Spending Continues to Soar in the U.S.

TUESDAY, Dec. 27, 2016 (HealthDay News) -- From 1996 to 2013 there were considerable increases in personal health care spending in the United States, with the highest amounts for diabetes, ischemic heart disease, and low back and neck pain, according to a study published in the Dec. 27 issue of the Journal of the American Medical Association.

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Most Postpartum Moms OK With Self-Administered Pain Meds

TUESDAY, Dec. 27, 2016 (HealthDay News) -- There is high satisfaction for a postpartum self-administered medication (SAM) program on postpartum wards, according to a study published online Dec. 20 in the Journal of Evaluation in Clinical Practice.

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Prior AKI Episode Linked to Risk of Adverse Pregnancy Outcomes

FRIDAY, Dec. 23, 2016 (HealthDay News) -- Women with recovered acute kidney injury (r-AKI) who become pregnant have increased risk of preeclampsia and adverse fetal outcomes, according to a study published online Dec. 22 in the Journal of the American Society of Nephrology.

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Early Surgery Ups Mortality Risk for Some Endometrial CA Patients

FRIDAY, Dec. 23, 2016 (HealthDay News) -- For patients diagnosed with endometrial cancer, surgery within the first two weeks of diagnosis is associated with increased risk of mortality, according to a study published online Dec. 8 in the American Journal of Obstetrics & Gynecology.

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Substance Use Higher Among Patients From LA Versus Tijuana

THURSDAY, Dec. 22, 2016 (HealthDay News) -- The prevalence of substance use is higher among patients from community health centers in Los Angeles (LA) versus Tijuana, Mexico, according to a study published online Dec. 21 in Substance Use & Misuse.

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ASCO Updates Guideline for SNB in Early-Stage Breast Cancer

THURSDAY, Dec. 22, 2016 (HealthDay News) -- Recommendations for use of sentinel node biopsy (SNB) in early-stage breast cancer are unchanged from 2014, according to a clinical practice guideline update published online Dec. 12 in the Journal of Clinical Oncology.

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Surgeon Input on Contralateral Prophylactic Mastectomy Needed

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- Many patients with newly diagnosed unilateral breast cancer consider contralateral prophylactic mastectomy (CPM), according to a study published online Dec. 21 in JAMA Surgery.

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ACOG Recommends Delayed Umbilical Cord Clamping

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- Delayed umbilical cord clamping is beneficial for most term and preterm infants, according to a Committee Opinion from the American College of Obstetrics and Gynecology (ACOG) published in the January issue of Obstetrics & Gynecology.

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Pritelivir Beats Valacyclovir for Genital HSV-2 Shedding

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- The novel herpes simplex virus (HSV) helicase-primase inhibitor pritelivir is more effective than valacyclovir for reducing genital HSV-2 shedding, according to a study published in the Dec. 20 issue of the Journal of the American Medical Association.

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Risk of Uterine Fibroids Found to Be Lower in Women Using Statins

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- The use of statins is associated with a lower risk of uterine fibroids and fibroid-related symptoms, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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Peripartum Aortic Dissection Risk Factors Examined in Marfan Sx

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- Pregnant patients with Marfan syndrome, particularly those with a dilating aortic root, are at high risk of aortic dissection during and following pregnancy, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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2002 to 2014 Saw Increase in Marijuana Use in Women

TUESDAY, Dec. 20, 2016 (HealthDay News) -- The prevalence of marijuana use increased among women from 2002 to 2014, and less than 10 percent of adult marijuana users report use for medical purposes, according to two research letters published online Dec. 19 in the Journal of the American Medical Association.

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USPSTF Recommends Against Routine HSV Screening

TUESDAY, Dec. 20, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus (HSV) infection in asymptomatic adolescents and adults, according to an final recommendation statement published in the Dec. 20 issue of the Journal of the American Medical Association.

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Guidance on Dietary Sugar Intake Based on Low-Quality Evidence

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Guidelines on dietary sugar intake are of poor quality, and the supporting evidence is of low quality, according to research published online Dec. 20 in the Annals of Internal Medicine.

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Health Care Provider Burnout Negatively Affects Quality, Safety

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Health care provider burnout is negatively associated with quality and safety of health care, according to a meta-analysis published recently in the Journal of General Internal Medicine.

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FDA Grants Fast-Track Approval to Ovarian Cancer Drug

MONDAY, Dec. 19, 2016 (HealthDay News) -- The drug Rubraca (rucaparib) has been granted accelerated approval by the U.S. Food and Drug Administration to treat advanced ovarian cancer.

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DEA Announces Critical Changes in Registration Renewal Process

MONDAY, Dec. 19, 2016 (HealthDay News) -- The Drug Enforcement Administration (DEA) has announced critical changes in its registration renewal process, according to a report published by the American Academy of Family Physicians.

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AAP Issues New Guidelines for Use of Human Donor Milk

MONDAY, Dec. 19, 2016 (HealthDay News) -- Use of donor milk is safe when appropriate measures are used to screen donors and collect, store, and pasteurize the milk, according to a policy statement from the American Academy of Pediatrics published online Dec. 19 in Pediatrics.

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Twitter Chatter About HPV Vaccine Mostly Positive

MONDAY, Dec. 19, 2016 (HealthDay News) -- Twitter conversations regarding the human papillomavirus (HPV) vaccine tend to be positive, according to a study published online Dec. 5 in the Journal of Medical Internet Research.

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Long-Term DPP4-Inhibitor Use Not Tied to Fracture Risk in T2DM

MONDAY, Dec. 19, 2016 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), long-term use of dipeptidyl peptidase-4 inhibitors (DPP4-Is) is not associated with fracture risk, according to a study published online Dec. 10 in Diabetes, Obesity and Metabolism.

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Cervicovaginal Secretions Contain HIV-Linked Immune Mediators

MONDAY, Dec. 19, 2016 (HealthDay News) -- Cervicovaginal secretions from pregnant and nonpregnant women contain HIV infectivity-linked immune mediators, although there is no difference in infectivity between pregnant and nonpregnant women, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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No Long-Term Increase in Exercise Levels for Pokémon Go

FRIDAY, Dec. 16, 2016 (HealthDay News) -- Pokémon Go provided a slight, short-term boost to adults' physical activity levels, but it didn't last, according to a study published in the Christmas issue of The BMJ.

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BRCA Testing, Not Mastectomies, Up After Angelina Jolie Editorial

FRIDAY, Dec. 16, 2016 (HealthDay News) -- After actress Angelina Jolie's 2013 New York Times editorial that announced her preventive double mastectomy, there was an increase in the number of women who were tested for the BRCA genes but no corresponding increase in mastectomy rates, according to research published in the Christmas 2016 issue of the The BMJ.

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MRI Ups Diagnostic Accuracy of Fetal Brain Abnormalities

FRIDAY, Dec. 16, 2016 (HealthDay News) -- Follow-up magnetic resonance imaging (MRI) after a mid-pregnancy ultrasound could help improve diagnosis of possible fetal brain abnormalities, according to a study published online Dec. 14 in The Lancet.

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Endometrial Microbiota May Be Linked to Success of IVF

THURSDAY, Dec. 15, 2016 (HealthDay News) -- The presence of a non-Lactobacillus-dominated microbiota in a receptive endometrium is associated with poor reproductive outcomes for women undergoing in vitro fertilization (IVF), according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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Zika-Related Birth Defects More Extensive Than Thought

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Zika's ability to damage the infant brain may be even more far-reaching and insidious than previously thought, two new studies suggest.

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FDA Issues New Safety Info on Use of Anesthesia

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Repeated or lengthy use -- longer than three hours -- of general anesthetic and sedation drugs may harm the developing brains of fetuses and children younger than 3 years old, the U.S. Food and Drug Administration warned Wednesday.

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Preeclampsia Linked to Risk of Maternal Retinal Disease

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- Preeclampsia is associated with increased risk of maternal retinal disease, especially traction detachments, retinal breaks, and diabetic retinopathy, according to a study published in the January issue of Obstetrics & Gynecology.

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Triple-Negative Breast Cancer Subtype Chemosensitive

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- For patients with triple-negative breast cancer (TNBC), a BRCA-deficiency (BRCA-D) subtype is chemosensitive, according to a study published online Dec. 13 in PLOS Medicine.

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Uterine Artery Embolism Can Help Avoid Hysterectomy for Fibroids

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Hysterectomy can often be avoided in patients with uterine fibroids undergoing uterine artery embolization, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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Neonatal Abstinence Syndrome Up in Rural-Born Infants

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Rural U.S. communities are seeing a sharp increase in infants with neonatal abstinence syndrome (NAS), according to a research letter published online Dec. 12 in JAMA Pediatrics.

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Prenatal Exposure to Maternal Stress May Raise Psoriasis Risk

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Prenatal exposure to maternal bereavement is associated with psoriasis only for children born to a mother who lost a partner/spouse or an older child, according to a study published online Dec. 7 in the British Journal of Dermatology.

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Universal Group B Streptococci Screening Not Cost-Effective

TUESDAY, Dec. 13, 2016 (HealthDay News) -- For women with a singleton pregnancy planning a repeat cesarean delivery, universal group B streptococci (GBS) screening is not cost-effective, according to a study published in the January issue of Obstetrics & Gynecology.

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CDC: U.S. Flu Vaccination Rates Low So Far This Season

MONDAY, Dec. 12, 2016 (HealthDay News) -- Only about two out of five Americans had gotten this season's flu vaccination as of early November, the U.S. Centers for Disease Control and Prevention reports.

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Rate of Psychiatric Drug Use About 16 Percent in U.S. Adults

MONDAY, Dec. 12, 2016 (HealthDay News) -- One in six U.S. adults take a psychiatric medication to treat conditions such as depression, anxiety, and insomnia, according to a study published online Dec. 12 in JAMA Internal Medicine.

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Social Isolation Can Adversely Affect Breast Cancer Survival

MONDAY, Dec. 12, 2016 (HealthDay News) -- Social isolation may impede long-term breast cancer survival, according to a study published online Dec. 12 in Cancer.

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CDC: Colombia Sees Increase in Zika-Related Microcephaly

MONDAY, Dec. 12, 2016 (HealthDay News) -- Colombia is now experiencing a sharp increase in cases of infant microcephaly, according to research published in the Dec. 9 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Duration of Estrogen Rx May Be Important Factor in Renal Health

MONDAY, Dec. 12, 2016 (HealthDay News) -- For midlife ovariectomized Long Evans rats, long-term estradiol (E2) treatment exerts detrimental effects on kidney health, despite lowering blood pressure, while short-term E2 lowers blood pressure and reduces renal damage, according to an experimental study published online Nov. 9 in American Journal of Physiology-Renal Physiology.

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CDC Finds Vaccination Coverage Varies for Adults With Diabetes

MONDAY, Dec. 12, 2016 (HealthDay News) -- Among adults with diagnosed diabetes, vaccination coverage varies, with influenza vaccination more prevalent than pneumococcal or hepatitis B vaccination, according to a December data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Age-Adjusted Mortality Rate Up From 2014 to 2015 in U.S.

FRIDAY, Dec. 9, 2016 (HealthDay News) -- There was an increase in the age-adjusted death rate from 2014 to 2015, and a decrease in life expectancy, according to a December data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Even Moderate, Regular Alcohol Consumption Could Cause A-Fib

THURSDAY, Dec. 8, 2016 (HealthDay News) -- Regularly drinking even small amounts of alcohol may increase the risk of atrial fibrillation, according to a study published in the Dec. 13 issue of the Journal of the American College of Cardiology.

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Suicide Risk Up for Patients With Acute Coronary Syndrome

THURSDAY, Dec. 8, 2016 (HealthDay News) -- Patients with acute coronary syndrome (ACS) may face a higher-than-normal risk of suicide, according to a study published online Dec. 7 in the Journal of the American Heart Association.

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Readings Taken in Clinic May Underestimate Ambulatory BP

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Ambulatory blood pressure may be a better indicator of health risks than clinic blood pressure, according to a new report published online Dec. 6 in Circulation.

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Dynamic Tool Ups Surgeon Awareness in Hysterectomy

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- A dynamic quality assessment tool could potentially improve surgeon performance and outcomes in laparoscopic hysterectomy, according to a study published in the December issue of the American Journal of Obstetrics and Gynecology.

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Prevalence of Disability 2.7 Percent at U.S. Medical Schools

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools, according to a research letter published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue of medical education.

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Number of Cancer Cases, Deaths Up Globally

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Cancer cases rose 33 percent worldwide in the past 10 years, according to a report published online Dec. 3 in JAMA Oncology.

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Learning Interventions Can Improve Med Student Well-Being

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Specific learning interventions may improve emotional well-being among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Pubic Hair Grooming Tied to Heightened Risk of STIs

TUESDAY, Dec. 6, 2016 (HealthDay News) -- Frequent groomers of pubic hair are three to four times more likely to contract a sexually transmitted infection, such as herpes, human papillomavirus, or syphilis, according to a study published online Dec. 5 in Sexually Transmitted Infections.

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Depression, Suicide Ideation Prevalent in Medical Students

TUESDAY, Dec. 6, 2016 (HealthDay News) -- The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent, respectively, among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Low Thromboembolism Risk for Contraceptive Use in Diabetes

TUESDAY, Dec. 6, 2016 (HealthDay News) -- For women with diabetes who are using hormonal contraception, the absolute risk of thromboembolism is low, with the lowest rates seen with use of intrauterine and subdermal contraceptives, according to a study published online Nov. 29 in Diabetes Care.

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Menopausal Status Linked to Faster Lung Function Decline

TUESDAY, Dec. 6, 2016 (HealthDay News) -- Menopausal status is associated with accelerated lung function decline, according to a study published online Dec. 1 in the American Journal of Respiratory and Critical Care Medicine.

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Biosimilar Promising for ERBB2+ Breast Cancer Treatment

MONDAY, Dec. 5, 2016 (HealthDay News) -- A proposed biosimilar is comparable to trastuzumab for women with ERBB2-positive metastatic breast cancer, according to a study published online Dec. 1 in the Journal of the American Medical Association.

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Announcement Training Ups HPV Vaccination for Adolescents

MONDAY, Dec. 5, 2016 (HealthDay News) -- Training providers to use announcements can increase human papillomavirus (HPV) vaccination coverage in young adolescents, according to a study published online Dec. 5 in Pediatrics.

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Multimodal Breast Cancer Tx May Up Cytokines, Comorbidities

MONDAY, Dec. 5, 2016 (HealthDay News) -- Breast cancer survivors who undergo multimodal treatment have higher cytokines and comorbidities than controls without cancer, according to a study published online Nov. 28 in the Journal of Clinical Oncology.

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Three Low-Carb Meals a Day Can Lower Insulin Resistance

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Eating low-carbohydrate meals may lead to healthy changes in a woman's metabolism that don't occur when consuming higher-carbohydrate meals, and the timing of exercise may play a role in how beneficial it is for metabolism, according to research published recently in PLOS ONE.

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Vitamin D in Pregnancy Might Help Prevent MS in Offspring

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Newborns with low levels of vitamin D may have higher odds of developing multiple sclerosis (MS) later in life, according to a study published online Nov. 30 in Neurology.

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Meds Don't Cut Trastuzumab-Tied Left Ventricular Remodeling

FRIDAY, Dec. 2, 2016 (HealthDay News) -- For patients with human epidermal growth factor receptor 2-overexpressing (HER2-positive) early breast cancer, perindopril and bisoprolol do not prevent trastuzumab-mediated left ventricular remodeling, according to a study published online Nov. 28 in the Journal of Clinical Oncology.

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Delayed Diagnosis for Many Women With PCOS

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Many women diagnosed with polycystic ovary syndrome (PCOS) report delayed diagnosis and receiving inadequate information, according to a study published online Dec. 1 in the Journal of Clinical Endocrinology & Metabolism.

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Alcohol Intake Linked to Increase in Risk of Melanoma

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Alcohol intake is associated with increased risk of melanoma, especially in relatively ultraviolet (UV)-spared areas, according to a study published in the December issue of Cancer, Epidemiology, Biomarkers & Prevention.

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Dabigatran May Be Better Than Warfarin After Bleeding Episode

FRIDAY, Dec. 2, 2016 (HealthDay News) -- Dabigatran is less likely than warfarin to cause recurrent bleeding in atrial fibrillation patients who have experienced a major bleeding event, according to a study published online Dec. 1 in Stroke.

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AND: Vegetarian Diet a Healthy, Environmentally Sound Choice

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Vegetarian diets are healthy for people of all ages, as well as the environment, according to a new position statement from the Academy of Nutrition and Dietetics (AND). The report has been published in the December issue of the Journal of the Academy of Nutrition and Dietetics.

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More HIV Patients Exhibiting Multidrug Resistance

THURSDAY, Dec. 1, 2016 (HealthDay News) -- A significant number of patients with HIV have strains of the virus that are resistant to both older and newer drugs, according to research published online Nov. 30 in The Lancet Infectious Diseases.

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Study Supports Smoking Cessation for Smokers of Any Age

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Age at smoking initiation and cessation continue to be important predictors of mortality in U.S. adults over age 70, according to a study published online Nov. 29 in the American Journal of Preventive Medicine.

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Frailty Screening Initiative Cuts Mortality After Surgery

THURSDAY, Dec. 1, 2016 (HealthDay News) -- For patients undergoing elective surgery, implementation of the Frailty Screening Initiative (FSI) is associated with a reduction in mortality, according to a study published online Nov. 30 in JAMA Surgery.

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Participation in Specific Sports Tied to Significant Health Benefits

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Participation in specific sports may have significant benefits for public health, according to a study published online Nov. 28 in the British Journal of Sports Medicine.

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Dapivirine Vaginal Ring Can Help Prevent HIV-1 Infection

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Use of a vaginal ring containing dapivirine is efficacious for prevention of HIV-1 infection, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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CDC: Fewer U.S. Families Struggling to Pay Medical Bills

THURSDAY, Dec. 1, 2016 (HealthDay News) -- The number of people in families having problems paying medical bills fell by nearly 13 million from 2011 through the first six months of 2016, according to a report published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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