December 2016 Briefing - Infectious Disease

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Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for December 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Recurrence Is Low One Year After Eradication of H. pylori Infection

FRIDAY, Dec. 30, 2016 (HealthDay News) -- The recurrence of Helicobacter pylori infection one year after eradication is low, according to a study published online Dec. 27 in the Journal of Digestive Diseases.

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Ledipasvir-Sofosbuvir Effective for Chronic HCV in Adolescents

FRIDAY, Dec. 30, 2016 (HealthDay News) -- For adolescents with chronic hepatitis C virus (HCV) genotype 1 infection, ledipasvir-sofosbuvir is highly effective, according to a study published online Dec. 20 in Hepatology.

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Pharmacy-Based Sale of Chlamydia Test Kits Is Effective

FRIDAY, Dec. 30, 2016 (HealthDay News) -- It is feasible to sell chlamydia test kits through pharmacies and use existing health infrastructure to follow up on results and manage clients, according to a pilot study published online Dec. 23 in the Journal of Pharmacy Practice and Research.

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Increase in HPV Prevalence Seen After Renal Transplant in Women

THURSDAY, Dec. 29, 2016 (HealthDay News) -- An increase in human papillomavirus (HPV) prevalence after renal transplantation (RT) may result from reactivation of latent HPV infections in women, according to a study published online Dec. 23 in the American Journal of Transplantation.

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Bell's Palsy Tied to Quadrivalent Meningococcal Vaccine

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- Bell's palsy is the only prespecified adverse event associated with the MenACWY-CRM quadrivalent meningococcal conjugate vaccine, according to a study published online Dec. 26 in Pediatrics.

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Ciprofloxacin Plus Fluocinolone More Effective for Peds AOMT

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- For children with acute otitis media with tympanostomy tubes (AOMT), ciprofloxacin plus fluocinolone is more effective than ciprofloxacin or fluocinolone alone, according to a study published online Dec. 22 in JAMA Otolaryngology-Head & Neck Surgery.

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Optimal Timing ID'd for Flu Shot During Three-Week Chemo Cycle

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- For adults with solid cancer undergoing three-week cytotoxic chemotherapy cycles, antibody responses are comparable for influenza vaccination on day one and 11, according to a study published online Dec. 20 in Cancer.

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Personal Health Care Spending Continues to Soar in the U.S.

TUESDAY, Dec. 27, 2016 (HealthDay News) -- From 1996 to 2013 there were considerable increases in personal health care spending in the United States, with the highest amounts for diabetes, ischemic heart disease, and low back and neck pain, according to a study published in the Dec. 27 issue of the Journal of the American Medical Association.

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Recombinant Type-5 Vector-Based Ebola Vaccine Safe

TUESDAY, Dec. 27, 2016 (HealthDay News) -- For healthy adults from Sierra Leon, the recombinant type-5 vector-based Ebola vaccine is safe and immunogenic, according to a study published online Dec. 21 in The Lancet.

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Chronic Hepatitis B Prevalence Higher in Those With T2DM

FRIDAY, Dec. 23, 2016 (HealthDay News) -- Patients with type 2 diabetes have higher prevalence of chronic hepatitis B virus infection (CHB), according to a study published online Dec. 8 in the Journal of Diabetes Investigation.

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Antiseptics Not Needed for Cord Care in Developed Nations

THURSDAY, Dec. 22, 2016 (HealthDay News) -- Dry cord care is noninferior to the use of antiseptics in preventing omphalitis in full-term newborns in France, according to a study published online Dec. 22 in Pediatrics.

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Mouthwash May Be Useful for Gonorrhea Control

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- Listerine mouthwash may be potentially useful for gonorrhea control, according to a study published online Dec. 20 in Sexually Transmitted Infections.

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Pritelivir Beats Valacyclovir for Genital HSV-2 Shedding

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- The novel herpes simplex virus (HSV) helicase-primase inhibitor pritelivir is more effective than valacyclovir for reducing genital HSV-2 shedding, according to a study published in the Dec. 20 issue of the Journal of the American Medical Association.

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Incidence of Nontyphoidal Salmonella Infections Estimated

WEDNESDAY, Dec. 21, 2016 (HealthDay News) -- There are about 6,200 resistant culture-confirmed nontyphoidal Salmonella infections annually, according to a study published in the January issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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USPSTF Recommends Against Routine HSV Screening

TUESDAY, Dec. 20, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus (HSV) infection in asymptomatic adolescents and adults, according to an final recommendation statement published in the Dec. 20 issue of the Journal of the American Medical Association.

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Daily Text Messaging Ups ART Adherence in Youth

TUESDAY, Dec. 20, 2016 (HealthDay News) -- A two-way, personalized daily text messaging intervention can improve antiretroviral therapy (ART) adherence among HIV-positive adolescents and young adults, according to a study published in AIDS and Behavior.

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Health Care Provider Burnout Negatively Affects Quality, Safety

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Health care provider burnout is negatively associated with quality and safety of health care, according to a meta-analysis published recently in the Journal of General Internal Medicine.

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DEA Announces Critical Changes in Registration Renewal Process

MONDAY, Dec. 19, 2016 (HealthDay News) -- The Drug Enforcement Administration (DEA) has announced critical changes in its registration renewal process, according to a report published by the American Academy of Family Physicians.

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Twitter Chatter About HPV Vaccine Mostly Positive

MONDAY, Dec. 19, 2016 (HealthDay News) -- Twitter conversations regarding the human papillomavirus (HPV) vaccine tend to be positive, according to a study published online Dec. 5 in the Journal of Medical Internet Research.

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Cervicovaginal Secretions Contain HIV-Linked Immune Mediators

MONDAY, Dec. 19, 2016 (HealthDay News) -- Cervicovaginal secretions from pregnant and nonpregnant women contain HIV infectivity-linked immune mediators, although there is no difference in infectivity between pregnant and nonpregnant women, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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Diabetes Ups Risk of HCC, Death in Patients With Hepatitis C

MONDAY, Dec. 19, 2016 (HealthDay News) -- For hepatitis C virus (HCV)-infected patients, diabetes mellitus (DM) is associated with increased risk of hepatocellular carcinoma (HCC) development and all-cause mortality, according to a study published online Dec. 8 in the Journal of Gastroenterology and Hepatology.

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Kingella kingae Keratitis Described in HIV-Positive Adult

FRIDAY, Dec. 16, 2016 (HealthDay News) -- A case of Kingella kingae keratitis in an HIV-positive adult male is described in a letter to the editor published online Dec. 12 in Clinical & Experimental Ophthalmology.

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Bacterial Cause of Periodontal Disease May Drive RA

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Specific bacteria may help explain the connection between periodontal disease and rheumatoid arthritis, according to a study published online Dec. 14 in Science Translational Medicine.

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Zika-Related Birth Defects More Extensive Than Thought

THURSDAY, Dec. 15, 2016 (HealthDay News) -- Zika's ability to damage the infant brain may be even more far-reaching and insidious than previously thought, two new studies suggest.

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Cetuximab + Chemoradiation Can Cure HIV-Associated Anal Cancer

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- Definitive chemoradiation (CRT) can potentially cure HIV-associated squamous cell carcinoma of the anal canal (SCCAC), with the addition of cetuximab resulting in less locoregional failure (LRF), according to a study published online Dec. 12 in the Journal of Clinical Oncology.

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Outcomes-Based Pricing Suggested for New, Costly Drugs

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- Outcomes-based pricing for novel and expensive biopharmaceuticals is supported in an Ideas and Opinions piece published online Dec. 13 in the Annals of Internal Medicine.

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Universal Group B Streptococci Screening Not Cost-Effective

TUESDAY, Dec. 13, 2016 (HealthDay News) -- For women with a singleton pregnancy planning a repeat cesarean delivery, universal group B streptococci (GBS) screening is not cost-effective, according to a study published in the January issue of Obstetrics & Gynecology.

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CDC: U.S. Flu Vaccination Rates Low So Far This Season

MONDAY, Dec. 12, 2016 (HealthDay News) -- Only about two out of five Americans had gotten this season's flu vaccination as of early November, the U.S. Centers for Disease Control and Prevention reports.

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CDC: Colombia Sees Increase in Zika-Related Microcephaly

MONDAY, Dec. 12, 2016 (HealthDay News) -- Colombia is now experiencing a sharp increase in cases of infant microcephaly, according to research published in the Dec. 9 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Fecal Microbiota Transplant Cost-Effective for Preventing CDI

MONDAY, Dec. 12, 2016 (HealthDay News) -- Use of fecal microbiota transplantation (FMT) is cost-effective for recurrent Clostridium difficile infection (CDI), according to a study published in the December issue of the Journal of Gastroenterology and Hepatology.

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CDC Finds Vaccination Coverage Varies for Adults With Diabetes

MONDAY, Dec. 12, 2016 (HealthDay News) -- Among adults with diagnosed diabetes, vaccination coverage varies, with influenza vaccination more prevalent than pneumococcal or hepatitis B vaccination, according to a December data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Screening Cuts Transfusion-Transmitted Babesiosis Risk

FRIDAY, Dec. 9, 2016 (HealthDay News) -- Screening for Babesia microti antibodies and DNA in blood-donation samples is associated with a reduction in the risk of transfusion-transmitted babesiosis, according to a study published in the Dec. 8 issue of the New England Journal of Medicine.

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Prevalence of Disability 2.7 Percent at U.S. Medical Schools

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools, according to a research letter published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue of medical education.

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Learning Interventions Can Improve Med Student Well-Being

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Specific learning interventions may improve emotional well-being among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Pubic Hair Grooming Tied to Heightened Risk of STIs

TUESDAY, Dec. 6, 2016 (HealthDay News) -- Frequent groomers of pubic hair are three to four times more likely to contract a sexually transmitted infection, such as herpes, human papillomavirus, or syphilis, according to a study published online Dec. 5 in Sexually Transmitted Infections.

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Depression, Suicide Ideation Prevalent in Medical Students

TUESDAY, Dec. 6, 2016 (HealthDay News) -- The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent, respectively, among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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HPV16 DNA From Fine-Needle Aspirations OK for Diagnosis

TUESDAY, Dec. 6, 2016 (HealthDay News) -- HPV16 DNA detected in fine-needle aspirations from neck masses is a reliable indicator for diagnosis of an HPV-positive oropharyngeal squamous cell carcinoma (SCC), according to a study published Nov. 29 in Head & Neck.

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Announcement Training Ups HPV Vaccination for Adolescents

MONDAY, Dec. 5, 2016 (HealthDay News) -- Training providers to use announcements can increase human papillomavirus (HPV) vaccination coverage in young adolescents, according to a study published online Dec. 5 in Pediatrics.

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More HIV Patients Exhibiting Multidrug Resistance

THURSDAY, Dec. 1, 2016 (HealthDay News) -- A significant number of patients with HIV have strains of the virus that are resistant to both older and newer drugs, according to research published online Nov. 30 in The Lancet Infectious Diseases.

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Dapivirine Vaginal Ring Can Help Prevent HIV-1 Infection

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Use of a vaginal ring containing dapivirine is efficacious for prevention of HIV-1 infection, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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Newborn Screen IDs Previously Unknown Cause of SCID

THURSDAY, Dec. 1, 2016 (HealthDay News) -- Mutant BCL11B has been identified as a cause of severe combined immunodeficiency (SCID) in newborn screening, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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CDC: Fewer U.S. Families Struggling to Pay Medical Bills

THURSDAY, Dec. 1, 2016 (HealthDay News) -- The number of people in families having problems paying medical bills fell by nearly 13 million from 2011 through the first six months of 2016, according to a report published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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