December 2016 Briefing - Gastroenterology

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Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for December 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Recurrence Is Low One Year After Eradication of H. pylori Infection

FRIDAY, Dec. 30, 2016 (HealthDay News) -- The recurrence of Helicobacter pylori infection one year after eradication is low, according to a study published online Dec. 27 in the Journal of Digestive Diseases.

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Lactobacillus Supplement Doesn't Impact HbA1c in Type 2 Diabetes

FRIDAY, Dec. 30, 2016 (HealthDay News) -- For patients with type 2 diabetes on insulin therapy, oral supplementation with Lactobacillus reuteri DSM 17938 does not affect glycated hemoglobin (HbA1c), according to a study published online Dec. 23 in Diabetes, Obesity and Metabolism.

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Ledipasvir-Sofosbuvir Effective for Chronic HCV in Adolescents

FRIDAY, Dec. 30, 2016 (HealthDay News) -- For adolescents with chronic hepatitis C virus (HCV) genotype 1 infection, ledipasvir-sofosbuvir is highly effective, according to a study published online Dec. 20 in Hepatology.

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Case Report: Ustekinumab for Crohn's Continued in Pregnancy

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- Good outcome has been reported in a pregnant woman who continued ustekinumab (UST) therapy for Crohn's disease during pregnancy, according to a case report published online Dec. 22 in the Journal of Clinical Pharmacy and Therapeutics.

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Gastric Bypass Associated With Reduced Risk of Psoriasis

WEDNESDAY, Dec. 28, 2016 (HealthDay News) -- Gastric bypass, but not gastric banding, is associated with reduced risk of psoriasis, progression to severe psoriasis, and psoriatic arthritis, according to a study published online Dec. 21 in JAMA Surgery.

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Personal Health Care Spending Continues to Soar in the U.S.

TUESDAY, Dec. 27, 2016 (HealthDay News) -- From 1996 to 2013 there were considerable increases in personal health care spending in the United States, with the highest amounts for diabetes, ischemic heart disease, and low back and neck pain, according to a study published in the Dec. 27 issue of the Journal of the American Medical Association.

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Rifaximin Effective for Repeat Treatment of IBS With Diarrhea

TUESDAY, Dec. 27, 2016 (HealthDay News) -- Repeat treatment with the nonsystemic antibiotic rifaximin is effective in patients with relapsing symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D), according to a study published in the December issue of Gastroenterology.

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Recombinant Type-5 Vector-Based Ebola Vaccine Safe

TUESDAY, Dec. 27, 2016 (HealthDay News) -- For healthy adults from Sierra Leon, the recombinant type-5 vector-based Ebola vaccine is safe and immunogenic, according to a study published online Dec. 21 in The Lancet.

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Fecal Calprotectin Levels ID Severity of Crohn's in Small Bowel

FRIDAY, Dec. 23, 2016 (HealthDay News) -- Fecal calprotectin (FC) levels correlate with the severity of Crohn's disease (CD) of the small bowel, as identified by balloon-assisted enteroscopy and computed tomography enterography (CTE), according to a study published in the January issue of Clinical Gastroenterology and Hepatology.

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Chronic Hepatitis B Prevalence Higher in Those With T2DM

FRIDAY, Dec. 23, 2016 (HealthDay News) -- Patients with type 2 diabetes have higher prevalence of chronic hepatitis B virus infection (CHB), according to a study published online Dec. 8 in the Journal of Diabetes Investigation.

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PPI Cuts Risk of Warfarin-Related Upper GI Bleeding

FRIDAY, Dec. 23, 2016 (HealthDay News) -- For patients beginning warfarin therapy, proton pump inhibitor (PPI) co-therapy is associated with reduced risk of upper gastrointestinal bleeding, according to a study published in the December issue of Gastroenterology.

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Vigorous IV Hydration Regimen Cuts Post-ERCP Pancreatitis Risk

THURSDAY, Dec. 22, 2016 (HealthDay News) -- Vigorous periprocedural intravenous fluid resuscitation (IVFR) with lactated Ringer's solution can reduce the incidence and severity of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in average-risk and high-risk cases, according to a study published in the January issue of Clinical Gastroenterology and Hepatology.

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Regular Aspirin Use Linked to Reduced Risk of Pancreatic CA

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Regular aspirin use is associated with reduced risk of pancreatic cancer in a Chinese cohort, according to a study published online Dec. 20 in Cancer Epidemiology, Biomarkers & Prevention.

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Health Care Provider Burnout Negatively Affects Quality, Safety

TUESDAY, Dec. 20, 2016 (HealthDay News) -- Health care provider burnout is negatively associated with quality and safety of health care, according to a meta-analysis published recently in the Journal of General Internal Medicine.

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DEA Announces Critical Changes in Registration Renewal Process

MONDAY, Dec. 19, 2016 (HealthDay News) -- The Drug Enforcement Administration (DEA) has announced critical changes in its registration renewal process, according to a report published by the American Academy of Family Physicians.

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Diabetes Ups Risk of HCC, Death in Patients With Hepatitis C

MONDAY, Dec. 19, 2016 (HealthDay News) -- For hepatitis C virus (HCV)-infected patients, diabetes mellitus (DM) is associated with increased risk of hepatocellular carcinoma (HCC) development and all-cause mortality, according to a study published online Dec. 8 in the Journal of Gastroenterology and Hepatology.

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CTA Can Diagnose Partially Obstructed IVC in Budd-Chiari

FRIDAY, Dec. 16, 2016 (HealthDay News) -- For patients with Budd-Chiari syndrome (BCS), computed tomographic angiography (CTA) has high diagnostic accuracy for partially obstructed inferior vena cava (IVC), according to a study published online Nov. 29 in the Journal of Gastroenterology and Hepatology.

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CRC in Patients Under 50 Often Caused by Genetic Mutations

FRIDAY, Dec. 16, 2016 (HealthDay News) -- As many as one in six colorectal cancer patients under the age of 50 have genetic traits that greatly increase the risk of cancer, according to a study published online Dec. 15 in JAMA Oncology.

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Addiction Consultation Valuable for Liver Transplant Patients

WEDNESDAY, Dec. 14, 2016 (HealthDay News) -- Liver transplantation (LT) patients should undergo addiction consultation to accurately detect alcohol consumption, according to a study published online Dec. 9 in Alcoholism: Clinical & Experimental Research.

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Recommendations Developed for Pediatric NAFLD

TUESDAY, Dec. 13, 2016 (HealthDay News) -- Evidence-based recommendations have been developed for screening, diagnosis, and treatment of pediatric nonalcoholic fatty liver disease (NAFLD). The guidelines were published online Nov. 30 in the Journal of Pediatric Gastroenterology and Nutrition.

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Fecal Microbiota Transplant Cost-Effective for Preventing CDI

MONDAY, Dec. 12, 2016 (HealthDay News) -- Use of fecal microbiota transplantation (FMT) is cost-effective for recurrent Clostridium difficile infection (CDI), according to a study published in the December issue of the Journal of Gastroenterology and Hepatology.

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Cytotoxic T-Cells Can Induce Metastatic CRC Regression

FRIDAY, Dec. 9, 2016 (HealthDay News) -- Administration of cytotoxic T-cells targeting mutant KRAS G12D can induce tumor regression in metastatic colorectal cancer, according to a case report published in the Dec. 8 issue of the New England Journal of Medicine.

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Prevalence of Disability 2.7 Percent at U.S. Medical Schools

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools, according to a research letter published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue of medical education.

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Learning Interventions Can Improve Med Student Well-Being

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- Specific learning interventions may improve emotional well-being among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Bariatric Surgery Effective, Cost-Effective in Obese With NASH

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- For patients with nonalcoholic steatohepatitis (NASH), bariatric surgery is effective and cost-effective for obese patients, while for overweight patients, cost-effectiveness is limited to those with F3 fibrosis, according to a study published online Nov. 23 in Hepatology.

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Depression, Suicide Ideation Prevalent in Medical Students

TUESDAY, Dec. 6, 2016 (HealthDay News) -- The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent, respectively, among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Colonic Diverticular Disease May Increase Dementia Risk

TUESDAY, Dec. 6, 2016 (HealthDay News) -- Patients with colonic diverticular disease may be at an increased risk for dementia, according to a study published Nov. 23 in the Journal of Gastroenterology and Hepatology.

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Sleep Disturbance Linked to Esophageal Hypersensitivity

MONDAY, Dec. 5, 2016 (HealthDay News) -- For patients with gastroesophageal reflux disease (GERD), sleep disturbance is associated with enhanced heartburn perception to capsaicin infusion, according to a study published online Nov. 29 in the Journal of Gastroenterology and Hepatology.

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CDC: Fewer U.S. Families Struggling to Pay Medical Bills

THURSDAY, Dec. 1, 2016 (HealthDay News) -- The number of people in families having problems paying medical bills fell by nearly 13 million from 2011 through the first six months of 2016, according to a report published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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