DASH Diet Reduces Serum Uric Acid in Prehypertension

Share this content:
DASH Diet Reduces Serum Uric Acid in Prehypertension
DASH Diet Reduces Serum Uric Acid in Prehypertension

MONDAY, Dec. 5, 2016 (HealthDay News) -- Among adults with prehypertension or stage I hypertension, following the Dietary Approaches to Stop Hypertension (DASH) diet lowers serum uric acid (UA), according to a study published online Nov. 28 in Arthritis & Rheumatology.

Stephen P. Juraschek, M.D., Ph.D., from Johns Hopkins University in Baltimore, and colleagues conducted an ancillary study of a randomized crossover feeding trial in 103 adults with prehypertension or stage I hypertension. Participants were randomized to receive either the DASH diet or a control diet that was typical of an average American diet. They were further fed low, medium, and high levels of sodium for 30 days. At baseline and following each feeding period, serum UA level were measured.

The researchers found that serum UA was reduced with the DASH diet (−0.35 mg/dL), with a higher effect for those with a baseline serum UA level of ≥7 mg/dL (−1.29 mg/dL). Increasing sodium intake from the low level correlated with a reduction in serum UA during the medium and the high sodium intake periods (−0.3 and −0.4 mg/dL, respectively; both P < 0.001).

"The DASH diet lowered serum UA, and this effect was greater among participants with hyperuricemia," the authors write. "Moreover, we found that higher sodium intake decreased serum UA, which enhances our knowledge of urate pathophysiology and risk factors for hyperuricemia."

Several food companies donated food, and a food storage company provided food storage.

Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Some California Mosquitoes Can Carry Zika Virus

Some California Mosquitoes Can Carry Zika Virus

Aedes aegypti mosquitoes found to transmit Zika virus

Periodontal Inflammation a Risk With Tongue Piercing

Periodontal Inflammation a Risk With Tongue Piercing

And, two young females with tongue piercings have deep lingual infrabony lesions, periodontitis

Risk of OD Highest for First Days of Opioid  Benzodiazepine Use

Risk of OD Highest for First Days of ...

Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use

is free, fast, and customized just for you!




Already a member?

Sign In Now »