Daily Calcium Intake of 1,000 or 2,000 mg Best for Rickets

This article originally appeared here.
Share this content:
Daily Calcium Intake of 1,000 or 2,000 mg Best for Rickets
Daily Calcium Intake of 1,000 or 2,000 mg Best for Rickets

MONDAY, June 27, 2016 (HealthDay News) -- For children with rickets, radiographic healing is more rapid with 1,000 mg and 2,000 mg daily calcium intake compared with 500 mg, according to a study published online June 17 in the Journal of Bone and Mineral Research.

Tom D. Thacher, M.D., from the Mayo Clinic in Rochester, Minn., and colleagues examined the optimal dose of calcium for treatment of rickets in children. A cohort of 65 Nigerian children with radiographically-confirmed rickets were randomized to daily supplemental calcium intake of 500 mg, 1,000 mg, or 2,000 mg (21, 23, and 21 children, respectively).

The researchers observed improvement in the radiographic severity scores in all three groups, with significantly more rapid rates of healing in the 1,000 and 2,000 mg supplementation groups versus the 500 mg group. There was no difference in the rate of healing between the 1,000 and 2,000 mg groups. A radiographic score of 1.5 or less was achieved by 67, 87, and 67 percent of participants in the 2,000, 1,000, and 500 mg groups, respectively, after 24 weeks (P = 0.21). Similar decreases were seen in all groups in serum alkaline phosphatase and calcium.

"Daily calcium intakes of 1,000 mg or 2,000 mg produced more rapid radiographic healing of rickets than 500 mg, but 2,000 mg did not have greater benefit than 1,000 mg," the authors write.

One author disclosed financial ties to the biopharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Factors ID'd to Predict Fatty Liver in Obese Teens

Factors ID'd to Predict Fatty Liver in Obese ...

African-American obese teens more susceptible to fatty liver effects on glucose metabolism

Patients Prefer Doctors Who Engage in Face-to-Face Visits

Patients Prefer Doctors Who Engage in Face-to-Face Visits

Patients perceive F2F physicians as more compassionate and better communicators

Flexible Sigmoidoscopy Cuts CRC Incidence, Mortality in Men

Flexible Sigmoidoscopy Cuts CRC Incidence, Mortality in Men

Absolute risks for colorectal cancer, CRC death not reduced for screening group vs. controls in women

is free, fast, and customized just for you!

Already a member?

Sign In Now »