Cortisol Mediates Benefit for Early Session Psychotherapy

Share this content:
Cortisol Mediates Benefit for Early Session Psychotherapy
Cortisol Mediates Benefit for Early Session Psychotherapy

WEDNESDAY, Oct. 12, 2016 (HealthDay News) -- For patients with panic disorder with agoraphobia, cortisol mediates the effect of the time of day on subsequent outcome, with greater clinical improvement seen for earlier exposure sessions, according to a study published in the December issue of Psychoneuroendocrinology.

Alicia E. Meuret, Ph.D., from the Southern Methodist University in Dallas, and colleagues examined the role of cortisol levels as a mediator between time of day and therapeutic gains in 24 participants meeting Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, criteria for panic disorder with agoraphobia. Patients received three weekly in-vivo exposure sessions, yielding 72 total sessions, whose start times were distributed evenly throughout the day.

The researchers observed a correlation for sessions starting earlier in the day with superior therapeutic gains by the next therapy session. There was also a correlation for earlier sessions with higher pre-exposure cortisol levels, which in turn correlated with greater clinical improvement by the subsequent session.

"The data suggest that early-day extinction-based therapy sessions yield better outcomes than later-day sessions, partly due to the enhancing effect of higher cortisol levels," the authors write.

The study was funded by the Behavior Therapy Research Foundation.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Tai Chi Found to Be Beneficial for Veterans With PTSD

Tai Chi Found to Be Beneficial for Veterans ...

Chinese exercise regimen helps veterans cope with distressing symptoms of PTSD

Healthy Diet May Help Lengthen the Lives of CKD Patients

Healthy Diet May Help Lengthen the Lives of ...

Study found eating lots of fruit, vegetables, fish, whole grains was linked to lower rate of early death

Regular Cannabis Use May Affect Retinal Ganglion Cell Function

Regular Cannabis Use May Affect Retinal Ganglion Cell ...

May disrupt, delay signal transmitted along the visual pathway via the optic nerve

is free, fast, and customized just for you!

Already a member?

Sign In Now »