Confocal Microscopy Aids Surgical Removal of Tumors From Eyelid

Share this content:
Confocal Microscopy Aids Surgical Removal of Tumors From Eyelid
Confocal Microscopy Aids Surgical Removal of Tumors From Eyelid

TUESDAY, Dec. 27, 2016 (HealthDay News) -- Imaging using fluorescence confocal microscopy (FCM) analysis in the reflectance mode and with an "en face" scanning can control tumor margins of eyelid basal cell carcinoma (BCC) to optimize surgical management, according to a study published online Dec. 19 in Clinical & Experimental Ophthalmology.

Marine Espinasse, M.D., from University Hospital of St-Etienne in France, and colleagues evaluated the sensitivity and specificity of FCM for the presence of tumor-free margins in 41 patients undergoing excision of BCC of the eyelid. Histopathogical examination was later performed in order to compare the results of FCM in the reflectance mode and with a horizontal ("en face") scanning.

The researchers found that FCM results were consistent with histopathology in all cases. Tumor-free margins were seen in 40 out of 42 samples, yielding both a sensitivity and specificity for FCM of 100 percent.

"This procedure has the advantage on FCM performed in the fluorescent mode of not needing any contrast agent to examine the samples," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Approves Kinase Inhibitor for Treatment of AML

FDA Approves Kinase Inhibitor for Treatment of AML

Midostaurin, in combination with chemotherapy, treats acute myeloid leukemia in adults

Enzyme Replacement Drug OK'd for Form of Batten Disease

Enzyme Replacement Drug OK'd for Form of Batten ...

Brineura will be used to treat children with late infantile neuronal ceroid lipofuscinosis type 2 Batten

is free, fast, and customized just for you!

Already a member?

Sign In Now »