Combo Rx for Fibromyalgia Tied to Higher Adherence

This article originally appeared here.
Share this content:
Combo Rx for Fibromyalgia Tied to Higher Adherence
Combo Rx for Fibromyalgia Tied to Higher Adherence

FRIDAY, April 28, 2017 (HealthDay News) -- Medication adherence is better for combination prescription initiators with fibromyalgia syndrome (FMS), although expenditures for total health care are higher with combination prescriptions, according to a study published online April 18 in Pain Practice.

Nicole M. Marlow, Ph.D., from the University of Florida in Gainesville, and colleagues examined medication adherence and health care costs for combination prescription initiators (duloxetine/milnacipran/venlafaxine with pregabalin; 100 patients) versus monotherapy initiators (duloxetine, milnacipran, venlafaxine, and pregabalin; 1,771 patients combined) among patients with FMS. Claims data for the South Carolina Blue Cross Blue Shield State Health Plan were evaluated.

The researchers found that the odds ratios for high adherence were significantly increased (P < 0.05) among the combination cohort versus the venlafaxine (2.15), duloxetine (1.39), and pregabalin (2.20) cohorts. For the combination cohort, expenditures for total health care were significantly higher (P < 0.05) versus duloxetine ($26,291 versus $17,190), milnacipran ($33,638 versus $22,886), and venlafaxine ($26,586 versus $16,857) cohorts.

"Our findings suggest important clinical benefits with the use of combination prescription therapy, and prospective studies of medication adherence are warranted to examine causal relationships with outcomes not captured by health care claims databases," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Zika Does Not Appear to Last in Semen As Long As Thought

Zika Does Not Appear to Last in Semen ...

More research is needed to better inform public health recommendations

Radioiodine Therapy for Thyroid Cancer Doesn't Up Stroke Risk

Radioiodine Therapy for Thyroid Cancer Doesn't Up Stroke ...

I-131 therapy group showed no significantly higher risk of ischemic or hemorrhagic stroke

Higher Odds of Infection With Reduced Kidney Function

Higher Odds of Infection With Reduced Kidney Function

Study finds excess community-acquired infections incidence in individuals with mild to severe CKD

is free, fast, and customized just for you!

Already a member?

Sign In Now »