Clinician Suspicion Minimally Accurate for Lyme Disease

Share this content:
Clinician Suspicion Minimally Accurate for Lyme Disease
Clinician Suspicion Minimally Accurate for Lyme Disease

MONDAY, Nov. 27, 2017 (HealthDay News) -- Clinician suspicion has minimal accuracy for the diagnosis of Lyme disease, according to a study published online Nov. 24 in Pediatrics.

Lise E. Nigrovic, M.D., M.P.H., from the Boston Children's Hospital, and colleagues assembled a prospective cohort of children aged 1 to 21 years evaluated for Lyme disease to examine the accuracy of clinician suspicion. Treating physicians were asked to estimate the probability of Lyme disease, and the ability of clinician suspicion to diagnose Lyme disease was calculated as the area under the curve for the receiver operating curve. Lyme disease was defined as a patient with an erythema migrans lesion or positive two-tiered serology results for patients with compatible symptoms.

Overall, 1,021 children were enrolled, of whom, 23 percent had Lyme disease. The researchers found that clinician suspicion had a minimal ability to differentiate children with and without Lyme disease (area under the curve, 0.75). Twelve percent of the 554 children who the treating clinicians thought were unlikely to have Lyme disease had Lyme disease, and 31 percent of those who the treating clinicians thought were very likely to have Lyme disease did not have Lyme disease.

"Because clinician suspicion had only minimal accuracy for the diagnosis of Lyme disease, laboratory confirmation is required to avoid both under- and over-diagnosis," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease


Sign up for myCME e-newsletters


More in Home

Proinflammatory Diet Linked to Increased Colorectal Cancer Risk

Proinflammatory Diet Linked to Increased Colorectal Cancer Risk

Higher empirical dietary inflammatory pattern score linked to increased risk of CRC for men and women

Longer Duration of Post-Op Opioid Use Associated With Misuse

Longer Duration of Post-Op Opioid Use Associated With ...

Higher dose, shorter duration Rx may minimize risk of longer term misuse, authors say

Alcohol Induced DNA Repair Genes Prognostic in Gastric Cancer

Alcohol Induced DNA Repair Genes Prognostic in Gastric ...

BRF1, BRCA1/2, MPO induced by alcohol have prognostic value for patients with gastric cancer

is free, fast, and customized just for you!

Already a member?

Sign In Now »