Chronic Kidney Disease Adversely Affects Digestive Function

This article originally appeared here.
Share this content:
Chronic Kidney Disease Adversely Affects Digestive Function
Chronic Kidney Disease Adversely Affects Digestive Function

TUESDAY, June 14, 2016 (HealthDay News) -- Chronic kidney disease (CKD) has an adverse effect on digestive function, according to a study published online May 25 in the Journal of Gastroenterology and Hepatology.

Claire J. Grant, from the Lilibeth Caberto Kidney Clinical Research Unit in London, Canada, and colleagues conducted detailed gastrointestinal magnetic resonance imaging in fasted and fed states among 35 subjects without diabetes (12 with CKD stage 4/5 and 23 healthy controls). The authors assessed upper gastrointestinal function by quantification of gastric emptying and intra-luminal small bowel water.

The researchers observed correlations for CKD with dysmotility (P = 0.04) and reduced fasting and post-prandial small bowel water (P < 0.001), indicating abnormal digestive secretion and absorption. There was a correlation with the degree of endotoxemia (P = 0.04) and poorer symptom scores. No correlation was found with disease severity, arterial stiffness, or hydration status.

"CKD adversely affects digestive function," the authors write. "Abnormalities in digestive secretion and absorption may potentially have a broad impact in the prevention and treatment of both CKD and its complications."

The study was funded by Baxter Healthcare.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Dermatography Helps Lessen Appearance of Surgical Scars

Dermatography Helps Lessen Appearance of Surgical Scars

Pigments can restore more natural skin appearance that patients are happy with

Drug-Resistant Bacteria Live in America's Water Systems

Drug-Resistant Bacteria Live in America's Water Systems

Bacteria found in plumbing may sicken thousands each year

Deep Brain Stimulation May Improve TBI Symptoms

Deep Brain Stimulation May Improve TBI Symptoms

Deep brain stimulation appears to boost function and quality of life

is free, fast, and customized just for you!

Already a member?

Sign In Now »