Chlorhexidine Bathing Doesn't Cut Health Care-Linked Infections

This article originally appeared here.
Share this content:
Chlorhexidine Bathing Doesn't Cut Health Care-Linked Infections
Chlorhexidine Bathing Doesn't Cut Health Care-Linked Infections

TUESDAY, Jan. 27, 2015 (HealthDay News) -- For critically ill patients, chlorhexidine bathing does not reduce health-care-associated infections, according to a study published in the Jan. 27 issue of the Journal of the American Medical Association.

Michael J. Noto, M.D., Ph.D., from Vanderbilt University in Nashville, Tenn., and colleagues examined whether daily bathing of critically ill patients with chlorhexidine is associated with a reduction in the incidence of health care-associated infections. Data were collected from a pragmatic cluster randomized crossover study involving 9,340 patients admitted to five adult intensive care units from July 2012 through July 2013. Bathing treatments (once-daily bathing with disposable cloths impregnated with 2 percent chlorhexidine or nonantimicrobial cloths) were performed for a 10-week period, which was followed by a two-week washout period and then crossover to the alternative bathing treatment for 10 weeks.

The researchers found that there were 55 infections during the chlorhexidine bathing period and 60 during the control period. The rate of the primary outcome (composite of central line-associated bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and Clostridium difficile infections) was 2.86 per 1,000 patient-days during the chlorhexidine bathing period and 2.9 per 1,000 patient-days during the control period (rate difference, −0.004; P = 0.95). There was no between-group difference in the rate of primary outcome after adjustment for baseline variables.

"These findings do not support daily bathing of critically ill patients with chlorhexidine," the authors write.

One author disclosed financial ties to pharmaceutical companies; the chlorhexidine-impregnated and nonantimicrobial cloths were purchased from Sage Products.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

FDA OKs Doptelet for Liver Dz Patients Undergoing Procedures

FDA OKs Doptelet for Liver Dz Patients Undergoing ...

Doptelet reduces the need for platelet transfusion or any rescue therapy on day of procedure

Slower Decline in Lung Function With Anthocyanin Intake

Slower Decline in Lung Function With Anthocyanin Intake

Slower annual rates of decline in FEV1 and FVC for those in highest quartile of anthocyanin intake

Bioengineering Feasible for Airway Reconstruction

Bioengineering Feasible for Airway Reconstruction

Bioengineered tracheal and bronchial reconstruction reported using stented aortic matrices

is free, fast, and customized just for you!

Already a member?

Sign In Now »