Case Vignette Addresses Diagnosis, Management of PCOS

Share this content:
Case Vignette Addresses Diagnosis, Management of PCOS
Case Vignette Addresses Diagnosis, Management of PCOS

THURSDAY, July 7, 2016 (HealthDay News) -- The diagnosis and management of polycystic ovary syndrome is discussed in a case vignette published online July 6 in The New England Journal of Medicine.

Christopher R. McCartney, M.D., and John C. Marshall, M.D., from the University of Virginia School of Medicine, discussed evaluation and management of a 22-year-old woman reporting hirsutism and irregular menses. The symptoms worsened after weight gain in college. On physical examination, her body mass index was 29 kg/m² and blood pressure was 135/85 mmHg; she had moderate hirsutism without virilization.

The researchers note that since the patient had hyperandrogenism and oligomenorrhea, ovarian ultrasound was not necessary for a diagnosis of polycystic ovary syndrome. Treatment decisions should be informed by patient priorities, with hirsutism and irregular menses the primary concerns for this patient. In the absence of contraindication, a monophasic combined oral contraceptive with a low androgenic progestin was recommended; treatment would improve hirsutism, provide predictable withdrawal bleeding, and prevent endometrial hyperplasia. Clinical assessment at three months should include blood pressure and fasting lipid assessments. Additional pharmacologic therapy could include spironolactone for hirsutism, metformin for abnormal glucose tolerance, and clomiphene for ovulation induction.

"The patient can be counseled that live birth can be achieved by a majority of women with the polycystic ovary syndrome, although fertility treatment may be required," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Recent Decline in Prescription Opioid Use Among U.S. Teens

Recent Decline in Prescription Opioid Use Among U.S. ...

Lifetime prevalence of use peaked in 1989, 2002, and remained stable until decline in 2013 to 2015

Treatment Seeking Low Among Teens With Eating Disorders

Treatment Seeking Low Among Teens With Eating Disorders

Those with counter-stereotypic presentation even less likely to seek treatment

Optical Clearing Agent Ups No. of Laser Passes in Tattoo Removal

Optical Clearing Agent Ups No. of Laser Passes ...

Findings based on number of laser passes during a five-minute tattoo removal session

is free, fast, and customized just for you!

Already a member?

Sign In Now »