Cardiac Index Linked to Cerebral Blood Flow Regardless of CVD

This article originally appeared here.
Share this content:
Cardiac Index Linked to Cerebral Blood Flow Regardless of CVD
Cardiac Index Linked to Cerebral Blood Flow Regardless of CVD

MONDAY, Nov. 13, 2017 (HealthDay News) -- Among older adults, lower cardiac index is associated with lower resting cerebral blood flow (CBF) in the temporal lobes regardless of cardiovascular disease (CVD) but is not associated with cerebrovascular reactivity (CVR), according to a study published online Nov. 8 in Neurology.

Angela L. Jefferson, Ph.D., from the Vanderbilt Memory & Alzheimer's Center in Nashville, Tennessee, and colleagues studied 314 Vanderbilt Memory & Aging Project participants (aged 73±7 years) free of stroke, dementia, and heart failure. The authors examined the correlation between cardiac index and resting CBF and CVR.

The researchers found that there was a correlation for lower cardiac index with lower resting CBF in the left and right temporal lobes. When participants with prevalent CVD and atrial fibrillation were excluded, the results were similar. There was no correlation for cardiac index with CBF in other regions or with CVR in all regions. In secondary cardiac index × cognitive diagnosis interaction models, only in cognitively normal participants were cardiac index and CBF associations present, and these affected a majority of regions assessed, with strongest effects in the left and right temporal lobes.

"Among older adults without stroke, dementia, or heart failure, systemic blood flow correlates with cerebral CBF in the temporal lobe, independently of prevalent CVD, but not CVR," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

FDA Approves First Generic Under-the-Tongue Suboxone

FDA Approves First Generic Under-the-Tongue Suboxone

May only be prescribed by Drug Addiction Treatment Act-certified prescribers

Kellogg's Honey Smacks Cereal Recalled Due to Salmonella Risk

Kellogg's Honey Smacks Cereal Recalled Due to <i>Salmonella</i> ...

Twenty-four people have been hospitalized, but no deaths have been reported

Portable Music Player Use Linked to Hearing Loss in Children

Portable Music Player Use Linked to Hearing Loss ...

Increased odds of high-frequency hearing loss with portable music player use

is free, fast, and customized just for you!




Already a member?

Sign In Now »