Cancer Risk Up for RA Patients With Venous Thromboembolism

This article originally appeared here.
Share this content:
Cancer Risk Up for RA Patients With Venous Thromboembolism
Cancer Risk Up for RA Patients With Venous Thromboembolism

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Patients with rheumatoid arthritis (RA) and venous thromboembolism (VTE) have increased risk of cancer in the first year after VTE and during a longer follow-up period, according to a study published online Sept. 15 in the Journal of Thrombosis and Haemostasis.

Alma B. Pedersen, M.D., Ph.D., from Aarhus University Hospital in Denmark, and colleagues examined the cancer risk subsequent to VTE among RA patients. Patients with RA and a first-time diagnosis of VTE (index date) during 1978 to 2013 were included (2,497 patients) and compared with patients in an RA cohort without VTE (11,672 patients) and a general population without RA and without VTE (12,730 individuals).

The researchers found that the cumulative incidence of cancer within the first year of the index date was 3.2, 2.2, and 2 percent among RA patients with VTE, among RA patients without VTE, and in the general population cohort. The incidence rate ratios were 1.79 and 2.12 for RA patients with VTE versus RA patients without VTE and the general population, respectively. From more than one to 36 years after the index date, the incidence rate ratios of cancer for RA patients with VTE were 1.16 and 1.33 compared with RA patients without VTE and the general population, respectively.

"VTE may not only be a result of inflammation and immunological dysfunctions associated with RA, but may also be a marker for occult cancer," the authors write.

The Lundbeck Foundation and the Novo Nordisk Foundation established a program that provided grant funding for the study.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ACG: Diphenhydramine Ups Sedation in Chronic Opioid Users

ACG: Diphenhydramine Ups Sedation in Chronic Opioid Users

Improvement in sedation scores for patients using chronic opioids scheduled to undergo colonoscopy

Online Ratings Not Aligned With Objective Quality Measures

Online Ratings Not Aligned With Objective Quality Measures

In addition, consumer ratings are consistent across platforms for specialist physicians

Most Female Physicians Have Faced Sexist Patient Comments

Most Female Physicians Have Faced Sexist Patient Comments

Sexual harassment by patients can negatively affect physician-patient relationship, quality of care

is free, fast, and customized just for you!

Already a member?

Sign In Now »