Cancer Risk Up for RA Patients With Venous Thromboembolism

This article originally appeared here.
Share this content:
Cancer Risk Up for RA Patients With Venous Thromboembolism
Cancer Risk Up for RA Patients With Venous Thromboembolism

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Patients with rheumatoid arthritis (RA) and venous thromboembolism (VTE) have increased risk of cancer in the first year after VTE and during a longer follow-up period, according to a study published online Sept. 15 in the Journal of Thrombosis and Haemostasis.

Alma B. Pedersen, M.D., Ph.D., from Aarhus University Hospital in Denmark, and colleagues examined the cancer risk subsequent to VTE among RA patients. Patients with RA and a first-time diagnosis of VTE (index date) during 1978 to 2013 were included (2,497 patients) and compared with patients in an RA cohort without VTE (11,672 patients) and a general population without RA and without VTE (12,730 individuals).

The researchers found that the cumulative incidence of cancer within the first year of the index date was 3.2, 2.2, and 2 percent among RA patients with VTE, among RA patients without VTE, and in the general population cohort. The incidence rate ratios were 1.79 and 2.12 for RA patients with VTE versus RA patients without VTE and the general population, respectively. From more than one to 36 years after the index date, the incidence rate ratios of cancer for RA patients with VTE were 1.16 and 1.33 compared with RA patients without VTE and the general population, respectively.

"VTE may not only be a result of inflammation and immunological dysfunctions associated with RA, but may also be a marker for occult cancer," the authors write.

The Lundbeck Foundation and the Novo Nordisk Foundation established a program that provided grant funding for the study.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Medicaid Expansion Ups Preemptive Listing for Kidney Transplant

Medicaid Expansion Ups Preemptive Listing for Kidney Transplant

From pre- to post-expansion period, 59 percent relative increase in Medicaid-covered preemptive listings

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

BCG Vaccine Tied to Reduced Hyperglycemia in Type ...

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis

Many Physicians Not Prepared for End-of-Life Talks With Patients

Many Physicians Not Prepared for End-of-Life Talks With ...

Additional training, reimbursement may foster these critical conversations, authors say

is free, fast, and customized just for you!




Already a member?

Sign In Now »