Cancer Patients Vary in Survival Benefit Needed to Justify Chemo

This article originally appeared here.
Share this content:
Cancer Patients Vary in Survival Benefit Needed to Justify Chemo
Cancer Patients Vary in Survival Benefit Needed to Justify Chemo

MONDAY, March 27, 2017 (HealthDay News) -- Among patients participating in a chemotherapy drug trial, there is substantial variation in preferences regarding length of survival benefits that justify undergoing chemotherapy, according to a study published online March 21 in Cancer.

Ines Vaz-Luis, M.D., from the Dana-Farber Cancer Institute in Boston, and colleagues conducted a survey of breast cancer patients participating in a phase 3, randomized controlled adjuvant chemotherapy trial. At 18 months, the researchers assessed the survival benefit needed to justify six months of chemotherapy. Physicians who had enrolled patients in the study received a parallel survey.

The researchers found that of the 519 patients still participating at 18 months, 87.8 percent responded to the survey, as did 175 physicians. There was considerable variation in patient preferences, particularly for modest survival benefits. For two months of benefit, 57 percent would consider six months of chemotherapy, whereas 96 percent reported they would consider six months of chemotherapy for 24 months. Physicians were less likely to accept chemotherapy for modest benefit.

"Eliciting preferences regarding risks and benefits of adjuvant chemotherapy is critical," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Aspirin, Rivaroxaban Similar After Total Hip, Knee Arthroplasty

Aspirin, Rivaroxaban Similar After Total Hip, Knee Arthroplasty

Extended prophylaxis with aspirin no different from rivaroxaban for preventing venous thromboembolism

Odds of ARDS Up After Cardiac Surgery During Flu Season

Odds of ARDS Up After Cardiac Surgery During ...

Cardiac surgery during flu season is independent risk factor for acute respiratory distress syndrome

In A-Fib Patients, Stroke Risk Higher for Blacks Than Whites

In A-Fib Patients, Stroke Risk Higher for Blacks ...

Higher risk of ischemic stroke seen before, after atrial fibrillation diagnosis compared with whites

is free, fast, and customized just for you!

Already a member?

Sign In Now »