Bone Health Benefits Lacking for Vitamin D Supplements

This article originally appeared here.
Share this content:
Bone Health Benefits Lacking for Vitamin D Supplements
Bone Health Benefits Lacking for Vitamin D Supplements

TUESDAY, Aug. 4, 2015 (HealthDay News) -- High doses of vitamin D do not appear to protect postmenopausal women from osteoporosis, according to research published online Aug. 3 in JAMA Internal Medicine.

Karen Hansen, M.D., an associate professor of medicine at the University of Wisconsin School of Medicine and Public Health in Madison, and colleagues focused on 230 vitamin-D deficient postmenopausal women. Most were white, and all were under the age of 75. Between 2010 and 2013, the women were divided into three groups: a high-dose vitamin D group; a low-dose vitamin D group; and a placebo group. For one year, those in the low-dose group received 800 international units (IU) of vitamin D daily, while those in the high-dose group received 50,000 IU of vitamin D twice a month.

The researchers found that by year's end, the no-dose group saw their calcium absorption rate drop by 1.3 percent, while the low-dose groups experienced a decrease of 2 percent. In comparison, the high-dose group saw their rate increase by 1 percent. While the overall vitamin D level across all three groups was ultimately measured at 21 ng/mL, the high-dose group saw their levels rise to 30 ng/mL.

But despite the differences, tests revealed that the high-dose group showed no advantage over either the low-dose or no-dose group with respect to spine health, total bone mineral density, overall muscle mass, or physical mobility. Similarly, no differences between the groups were seen with respect to overall fall risk. The researchers cautioned that the findings may not apply to non-white women, young adults, women over the age of 75, or men.

One author disclosed financial ties to Takeda Pharmaceuticals.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Dermatography Helps Lessen Appearance of Surgical Scars

Dermatography Helps Lessen Appearance of Surgical Scars

Pigments can restore more natural skin appearance that patients are happy with

Drug-Resistant Bacteria Live in America's Water Systems

Drug-Resistant Bacteria Live in America's Water Systems

Bacteria found in plumbing may sicken thousands each year

Deep Brain Stimulation May Improve TBI Symptoms

Deep Brain Stimulation May Improve TBI Symptoms

Deep brain stimulation appears to boost function and quality of life

is free, fast, and customized just for you!

Already a member?

Sign In Now »