Basal Metabolic Rate Down After CPAP Initiation in OSA

Share this content:
Basal Metabolic Rate Down After CPAP Initiation in OSA
Basal Metabolic Rate Down After CPAP Initiation in OSA

THURSDAY, Nov. 10, 2016 (HealthDay News) -- For patients with obstructive sleep apnea (OSA), treatment with continuous positive airway pressure (CPAP) is associated with a decrease in basal metabolic rate (BMR), according to a study published recently in the American Journal of Respiratory and Critical Care Medicine.

Noting that treating OSA with CPAP may promote weight gain, Ryo Tachikawa, M.D., Ph.D., from Kyoto University in Japan, and colleagues conducted a comprehensive assessment of energy metabolism in 63 participants with newly diagnosed OSA, CPAP initiation, and a three-month follow-up.

The researchers found that BMR decreased significantly after CPAP (P < 0.001), while physical activity and total caloric intake did not change significantly. Significant predictors of ΔBMR included baseline apnea-hypopnea index, Δurine norepinephrine, and CPAP adherence. Higher leptin levels, lower ghrelin levels, and higher eating behavior scores were seen for weight gainers versus non-weight gainers. Increased caloric intake was a significant predictor of weight gain.

"Although a reduction in BMR after CPAP predisposes to a positive energy balance, dietary intake and eating behavior had greater impacts on weight change," the authors write. "These findings highlight the importance of lifestyle modifications combined with CPAP."

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Post-C-Section Cephalexin, Metronidazole Cuts SSI Rate

Post-C-Section Cephalexin, Metronidazole Cuts SSI Rate

Post-op course reduces rate of surgical site infection within 30 days of C-section among obese women

Multicomponent Intervention Linked to Greater Drop in BP

Multicomponent Intervention Linked to Greater Drop in BP

Intervention beneficial over 18 months for low-income adults in Argentina with uncontrolled HTN

Total of 0.21 Years Lost Due to Opioid-Related Poisoning Deaths

Total of 0.21 Years Lost Due to Opioid-Related ...

Drug-related poisoning deaths up from 2000 to 2015, with most of the increase due to opioid deaths

is free, fast, and customized just for you!

Already a member?

Sign In Now »