Bariatric Surgery Improves Adipose Tissue Function

This article originally appeared here.
Share this content:
Bariatric Surgery Improves Adipose Tissue Function
Bariatric Surgery Improves Adipose Tissue Function

MONDAY, June 20, 2016 (HealthDay News) -- Bariatric surgery is associated with improvements in adipose tissue function, some of which are independent of weight loss, according to research published online June 8 in Obesity Reviews.

Henriette Frikke-Schmidt, Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined how altered physiology of adipose tissue may contribute to the metabolic effects of bariatric surgery.

The researchers found that altered physiology of adipose tissue has specific effects on various fat depots, the function of individual adipocytes, and the interaction between adipose tissue and other metabolic tissues. Bariatric surgery alters the distribution of fat in addition to loss of fat mass, with fat shifting from visceral to the subcutaneous compartment favoring metabolic improvement. Furthermore, there were improvements in sensitivity toward lipolysis controlled by insulin and catecholamines, alterations in adipokine secretion, and decreases in local adipose inflammation and systemic inflammatory markers. Some of these changes were independent of weight loss and these effects could be explained by alterations in bile acid metabolism, gut microbiota, and central regulation of metabolism.

"In conclusion, bariatric surgery is capable of improving aspects of adipose tissue function and do so in some cases in ways that are not entirely explained by the potent effect of surgery," the authors write.

Several authors disclosed financial ties to the pharmaceutical, medical device, and nutrition industries.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Dermatography Helps Lessen Appearance of Surgical Scars

Dermatography Helps Lessen Appearance of Surgical Scars

Pigments can restore more natural skin appearance that patients are happy with

Drug-Resistant Bacteria Live in America's Water Systems

Drug-Resistant Bacteria Live in America's Water Systems

Bacteria found in plumbing may sicken thousands each year

Deep Brain Stimulation May Improve TBI Symptoms

Deep Brain Stimulation May Improve TBI Symptoms

Deep brain stimulation appears to boost function and quality of life

is free, fast, and customized just for you!

Already a member?

Sign In Now »