August 2017 Briefing - Pulmonology

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Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for August 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Stem Cell Factor Tied to Reduced Risk of Cardiac Events, Death

THURSDAY, Aug. 31, 2017 (HealthDay News) -- High levels of stem cell factor (SCF) are associated with reduced risk of mortality and cardiovascular events, according to a study published online Aug. 26 in the Journal of Internal Medicine.

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Minimal Evidence for Electronic Communication Guidelines

THURSDAY, Aug. 31, 2017 (HealthDay News) -- Minimal evidence is available for guidelines for electronic communication between patients and providers, according to research published online Aug. 28 in the Journal of the American Medical Informatics Association.

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Transvenous Pacemaker Complications Common, Costly

THURSDAY, Aug. 31, 2017 (HealthDay News) -- The incidence of complications for single- and dual-chamber transvenous pacemakers (TVPs) is considerable, reaching about 15 and 16 percent, respectively, by three years, with high associated costs, according to research published online Aug. 30 in JACC: Clinical Electrophysiology.

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Local Allergic Rhinitis Often Progresses Over Time

THURSDAY, Aug. 31, 2017 (HealthDay News) -- Patients with local allergic rhinitis (LAR) show worsening of rhinitis, greater tendency toward development of asthma, and impairment of quality of life after 10 years, but have a similar rate of development of allergic rhinitis with systemic atopy as controls, according to research published online Aug. 22 in Allergy.

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Proactive Approach Encouraged for Online Patient Reviews

WEDNESDAY, Aug. 30, 2017 (HealthDay News) -- Most patients are using online reviews as a first step to finding a new doctor, with 65 percent forming an opinion from reading one to six reviews, according to a report published in Medical Economics.

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Review Links Sleep-Disordered Breathing, Cognitive Impairment

WEDNESDAY, Aug. 30, 2017 (HealthDay News) -- Sleep-disordered breathing (SDB) is associated with increased likelihood of cognitive impairment, according to a review published online Aug. 28 in JAMA Neurology.

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Low Rate of Recurrence Seen for Serious Reactions to Vaccines

TUESDAY, Aug. 29, 2017 (HealthDay News) -- Severe vaccine reactions recur rarely, if ever, when a child receives the same vaccine again, or one with similar ingredients, according to a review published online Aug. 28 in Pediatrics.

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FDA Cites 'Significant Deviations' at Florida Stem Cell Clinic

TUESDAY, Aug. 29, 2017 (HealthDay News) -- A Florida stem cell clinic has received a warning letter from the U.S. Food and Drug Administration about what the agency describes as serious problems that could pose health risks to patients.

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Androgen-Deprivation Therapy May Carry Cardiovascular Risks

MONDAY, Aug. 28, 2017 (HealthDay News) -- Use of androgen-deprivation therapy (ADT) may increase the risk of certain cardiovascular conditions in men with prostate cancer, according to a study published online Aug. 24 in the British Journal of Cancer.

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Less Than Half of Seniors With A-Fib Receive Anticoagulants

MONDAY, Aug. 28, 2017 (HealthDay News) -- Less than 45 percent of older adults with atrial fibrillation (AF) admitted to the hospital are prescribed an anticoagulant, according to a study published online Aug. 21 in the Journal of the American Geriatrics Society.

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Tidal CO2 Prognostic for Chronic Thromboembolic Pulmonary HTN

MONDAY, Aug. 28, 2017 (HealthDay News) -- End-tidal carbon dioxide (ETCO2) levels are prognostic for patients with chronic thromboembolic pulmonary hypertension (CTEPH), according to a letter to the editor published online Aug. 14 in the Annals of the American Thoracic Society.

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Insufficient Sleep May Lead to Increased Risk-Taking Behavior

FRIDAY, Aug. 25, 2017 (HealthDay News) -- Chronic sleep restriction may lead to risk-seeking behavior, according to a study published online Aug. 21 in the Annals of Neurology.

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Only One-Third of Heart Attack Patients Enter Cardiac Rehab

FRIDAY, Aug. 25, 2017 (HealthDay News) -- Only one in three heart attack survivors in the United States attends outpatient cardiac rehabilitation, according to research published in the Aug. 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Asthma Tied to Later Inflammatory Bowel Disease

FRIDAY, Aug. 25, 2017 (HealthDay News) -- Asthma is associated with subsequent development of inflammatory bowel disease (IBD), according to a study published in the September issue of Clinical Gastroenterology and Hepatology.

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Cardiopulmonary Exercise Testing Prognostic in Aortic Stenosis

THURSDAY, Aug. 24, 2017 (HealthDay News) -- For patients judged as symptomatic or questionably symptomatic for aortic stenosis, an initially conservative management strategy results in good prognosis if cardiopulmonary exercise testing (CPET) does not indicate significant hemodynamic compromise, according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Intensive BP Treatment Appears Safe, Well Tolerated

THURSDAY, Aug. 24, 2017 (HealthDay News) -- For patients at increased risk of cardiovascular disease, intensive blood pressure control may be just as safe as standard treatment, and is likely cost-effective, according to research published in the Aug. 24 issue of the New England Journal of Medicine.

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Less REM May Indicate Higher Dementia Risk in Seniors

THURSDAY, Aug. 24, 2017 (HealthDay News) -- Seniors who spend less time each night in rapid eye movement (REM) sleep may be more likely to develop dementia as they age, according to a study published online Aug. 23 in Neurology.

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Worse LV Global Longitudinal Strain for STEMI With COPD

THURSDAY, Aug. 24, 2017 (HealthDay News) -- For patients with ST-segment elevation myocardial infarction (STEMI), those with chronic obstructive pulmonary disease (COPD) have significantly more impaired left ventricular (LV) global longitudinal strain (GLS), according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Patient Beliefs May Explain High Rate of Medicine Intake

THURSDAY, Aug. 24, 2017 (HealthDay News) -- Subjective norms and attitudes toward medicine consumption predict the intention and expectation to consume medicines, according to a study published online Aug. 19 in the Journal of Clinical Pharmacy and Therapeutics.

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Vitamin B6, B12 Supplements May Up Risk of Lung Cancer in Men

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Men, and especially male smokers, appear to be more likely to develop lung cancer if they take high doses of vitamins B6 and B12, according to a study published online Aug. 22 in the Journal of Clinical Oncology.

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Nurse-, System-Related Factors Analyzed in Wrong-Patient Events

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Greater focus is needed on correct identification processes in order to prevent wrong-patient medication administration incidents, and system supports for nurses are critical, according to a study published online Aug. 17 in the Journal of Clinical Nursing.

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Oral Corticosteroids No Benefit for LRI in Non-Asthmatic Adults

TUESDAY, Aug. 22, 2017 (HealthDay News) -- For adults without asthma, with acute cough and at least one lower respiratory tract symptom, prednisolone does not reduce cough duration or severity, according to a study published in the Aug. 22/29 issue of the Journal of the American Medical Association.

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NT-ProBNP-Guided Treatment No Benefit in High-Risk HFrEF

TUESDAY, Aug. 22, 2017 (HealthDay News) -- For high-risk patients with heart failure and reduced ejection fraction (HFrEF), an amino-terminal pro-B-type natriuretic peptide (NT-proBNP)-guided treatment strategy does not improve clinical outcomes versus usual care, according to a study published in the Aug. 22/29 issue of the Journal of the American Medical Association.

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Few Smokers Hospitalized With CHD Get Smoking Cessation Meds

TUESDAY, Aug. 22, 2017 (HealthDay News) -- Few smokers hospitalized for coronary heart disease (CHD) receive smoking cessation pharmacotherapy (SCP), according to a research letter published online Aug. 21 in JAMA Internal Medicine.

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Hours Worked Impacted by Kids for Female, Not Male Doctors

MONDAY, Aug. 21, 2017 (HealthDay News) -- For women, but not men, in dual-physician couples, weekly hours worked are lower for those with versus those without children, according to a research letter published online Aug. 21 in JAMA Internal Medicine.

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Once-Daily Triple-Tx Improves Lung Function, HRQoL in COPD

MONDAY, Aug. 21, 2017 (HealthDay News) -- For patients with chronic obstructive pulmonary disease (COPD), once-daily single-inhaler triple therapy is better for lung function and health-related quality of life than inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) therapy, according to a study published in the Aug. 15 issue of the American Journal of Respiratory and Critical Care Medicine.

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Procalcitonin Testing Not Impacting Antibiotic Rx for COPD

FRIDAY, Aug. 18, 2017 (HealthDay News) -- Hospital adoption of procalcitonin (PCT) testing has had little impact on antibiotic prescribing for chronic obstructive pulmonary disease (COPD) exacerbations, according to a study published online Aug. 10 in the Annals of the American Thoracic Society.

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Moderate, Severe OSA Linked to Elevated Blood Coagulability

FRIDAY, Aug. 18, 2017 (HealthDay News) -- Moderate and severe obstructive sleep apnea (OSA) are associated with elevated blood coagulability markers, according to a study published online Aug. 17 in JAMA Otolaryngology-Head & Neck Surgery.

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Worse Survival Seen for Alternative Vs Usual Cancer Rx

FRIDAY, Aug. 18, 2017 (HealthDay News) -- Patients who choose alternative medicine over traditional cancer treatments for curable cancers have a higher risk of dying early, according to research published online Aug. 10 in the Journal of the National Cancer Institute.

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Online Nursing Education Can Up Patient Use of VTE Prophylaxis

THURSDAY, Aug. 17, 2017 (HealthDay News) -- Online training for nurses has been found to increase hospital patients' use of venous thromboembolism (VTE) prophylaxis, according to a study published online Aug. 16 in PLOS ONE.

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Global Disease Burden of COPD, Asthma Quantified

THURSDAY, Aug. 17, 2017 (HealthDay News) -- In 2015, there were more deaths worldwide due to chronic obstructive pulmonary disease (COPD) than asthma, according to a study published online Aug. 16 in The Lancet Respiratory Medicine.

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Dietary Energy Density May Up Risk of Obesity-Linked Cancers

THURSDAY, Aug. 17, 2017 (HealthDay News) -- Higher dietary energy density (DED; the ratio of energy intake to food weight) is associated with increased risk of obesity-related cancers among normal-weight women, according to a study published online Aug. 17 in the Journal of the Academy of Nutrition and Dietetics.

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Study Highlights Readmit Factors Post Atrial Flutter Ablation

THURSDAY, Aug. 17, 2017 (HealthDay News) -- Recognition of factors associated with early readmission for patients after atrial flutter (AFL) ablation is necessary for reducing costs and improving quality of life, according to a study published online Aug. 11 in the Journal of Cardiovascular Electrophysiology.

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Risk Assessment Differs for Doctors, Heart Failure Patients

WEDNESDAY, Aug. 16, 2017 (HealthDay News) -- Physicians consider the majority of ambulatory patients with advanced heart failure on medical therapy to be at high risk for transplant, left ventricular assist device (LVAD) placement, and death, although patients rarely consider themselves at high risk, according to a study published online Aug. 16 in JACC: Heart Failure.

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Automated Analyses of Night Blood O2 Detects Apnea

WEDNESDAY, Aug. 16, 2017 (HealthDay News) -- Neural network-based automated analyses of nocturnal oximetry (nSpO2) recordings provide accurate identification of obstructive sleep apnea-hypopnea syndrome (OSA) severity among habitually snoring children, according to a study published online July 31 in the American Journal of Respiratory and Critical Care Medicine.

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'07 to '14 Saw Drop in Proportion Needing Dialysis After TAVI

WEDNESDAY, Aug. 16, 2017 (HealthDay News) -- From 2007 to 2014 there was a decrease in the proportion of patients needing dialysis after transcatheter aortic valve implantation (TAVI), according to a study published online Aug. 2 in JACC: Cardiovascular Interventions.

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Studies Used for FDA Approval of Device Changes Often Low Quality

TUESDAY, Aug. 15, 2017 (HealthDay News) -- Many studies used to support U.S. Food and Drug Administration approval of high-risk medical device modifications are not controlled; and efficacy of drugs granted accelerated approval is often confirmed three years after approval, according to two studies published in the Aug. 15 issue of the Journal of the American Medical Association.

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Specialist Access No Better With Adoption of Access Standards

TUESDAY, Aug. 15, 2017 (HealthDay News) -- Adoption of specialty access standards does not improve access to specialists, according to a study published online Aug. 14 in JAMA Internal Medicine.

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Exposure to Particulate Matter Linked to Metabolic Alterations

TUESDAY, Aug. 15, 2017 (HealthDay News) -- Exposure to particulate matter (PM) with aerodynamic diameters ≤2.5 µm is associated with metabolic alterations, according to a study published online Aug. 14 in Circulation.

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CPAP Doesn't Alter Renal Function in Coexisting OSA, CVD

FRIDAY, Aug. 11, 2017 (HealthDay News) -- For individuals with coexisting obstructive sleep apnea (OSA) and cardiovascular disease, continuous positive airway pressure (CPAP) does not alter renal function, according to a study published online July 25 in the American Journal of Respiratory and Critical Care Medicine.

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Live Attenuated Flu Vaccine Not Effective for Children in 2015-16

WEDNESDAY, Aug. 9, 2017 (HealthDay News) -- During the 2015 to 2016 season, influenza vaccines reduced the risk of influenza illness, but the live attenuated vaccine was ineffective among children 2 to 17 years of age, according to a study published in the Aug. 10 issue of the New England Journal of Medicine.

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Sleep-Disordered Breathing Linked to Cognitive Dysfunction

WEDNESDAY, Aug. 9, 2017 (HealthDay News) -- Sleep-disordered breathing is associated with cognitive deficits, with the strongest associations seen in apolipoprotein ε-4 (APOE-ε4) allele carriers, according to a study published online July 21 in the Annals of the American Thoracic Society.

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Higher Risk of CVD Persists After Hospital Stay for Severe Infection

WEDNESDAY, Aug. 9, 2017 (HealthDay News) -- There is an increased risk of cardiovascular disease following hospital admission for sepsis or pneumonia that persists for at least five years after the infection, according to a study published online Aug. 1 in the European Journal of Preventive Cardiology.

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Azithromycin Tied to Poor Airflow Decline-Free Survival After HSCT

TUESDAY, Aug. 8, 2017 (HealthDay News) -- For patients after allogeneic hematopoietic stem cell transplant (HSCT), early administration of azithromycin is associated with worse airflow decline-free survival, according to a study published in the Aug. 8 issue of the Journal of the American Medical Association.

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Probiotics in Infancy Do Not Reduce Incidence of Eczema

TUESDAY, Aug. 8, 2017 (HealthDay News) -- Probiotic administration during the first six months of life does not reduce the incidence of eczema at 2 years of age or asthma at 5 years of age, according to a study published online Aug. 7 in Pediatrics.

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Guidance Provided for Preventing Practice Billing Errors

MONDAY, Aug. 7, 2017 (HealthDay News) -- Strategies can help to prevent medical practice billing errors, according to a report published in Medical Economics.

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Epidemiology of Acute Otitis Media Changed From 2006-2016

MONDAY, Aug. 7, 2017 (HealthDay News) -- Since the introduction of pneumococcal vaccines, the epidemiology of acute otitis media (AOM) has changed considerably, but risk factors have not, according to a study published online Aug. 7 in Pediatrics.

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Occupational Exposures Linked to Interstitial Lung Disease

MONDAY, Aug. 7, 2017 (HealthDay News) -- Occupational exposures to vapors, gas, dust, and fumes (VGDF) are associated with high attenuation areas (HAA) and interstitial lung abnormalities (ILA), according to a study published online July 28 in the American Journal of Respiratory and Critical Care Medicine.

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Fluticasone Furoate Slows Loss of Lung Function in COPD

FRIDAY, Aug. 4, 2017 (HealthDay News) -- Regular use of fluticasone furoate (FF), either alone or in combination with vilanterol (VI), appears to reduce the rate of forced expiratory volume in one second (FEV1) decline in patients with moderate chronic obstructive pulmonary disease (COPD) and a high risk of cardiovascular disease, according to a study published online July 24 in the American Journal of Respiratory and Critical Care Medicine.

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Change in Conversion Definition May Improve TB Detection

THURSDAY, Aug. 3, 2017 (HealthDay News) -- A change of QuantiFERON-TB interferon (IFN)γ values from <0.2 to >0.7 IU/mL is associated with an increased incidence in the rate of tuberculosis, according to a study published online July 24 in the American Journal of Respiratory and Critical Care Medicine.

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Downregulation of miR-126 Augments DNA Damage Response

WEDNESDAY, Aug. 2, 2017 (HealthDay News) -- For cigarette smokers and patients with chronic obstructive pulmonary disease (COPD), downregulation of microRNA-126 (miR-126) augments DNA damage response (DDR), according to a letter to the editor published online July 28 in the American Journal of Respiratory and Critical Care Medicine.

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Revenue Exceeds Expenditures for Many ABMS Member Boards

WEDNESDAY, Aug. 2, 2017 (HealthDay News) -- Overall revenue exceeds expenditures for many American Board of Medical Specialties (ABMS) member boards, according to a study published in the Aug. 1 issue of the Journal of the American Medical Association.

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Periodontal Disease History Linked to Increased Cancer Risk

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Among older women, periodontal disease history is associated with increased total cancer risk, and with increased risk of several specific types of cancer, according to a study published in the Aug. 1 issue of Cancer, Epidemiology, Biomarkers & Prevention.

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Conservative Fluid Management Benefits Black ARDS Patients

TUESDAY, Aug. 1, 2017 (HealthDay News) -- For patients with acute respiratory distress syndrome (ARDS), conservative fluid management is associated with reduced mortality for non-Hispanic black, but not white, patients, according to a study published online July 14 in the Annals of the American Thoracic Society.

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Meta-Analysis Compares Efficacy of Therapies for Preventing TB

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Isoniazid monotherapy, rifampicin monotherapy, and combination therapies can be efficacious for preventing active tuberculosis (TB) among adults and children with latent TB infection (LTBI), according to research published online Aug. 1 in the Annals of Internal Medicine.

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Climate Change Expected to Up Premature Deaths From Pollution

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Increases in air pollution caused by rising temperatures will trigger an additional 60,000 premature deaths each year around the globe by 2030, and as many as 260,000 more premature deaths annually by 2100, according to findings from a new study published online July 31 in Nature Climate Change.

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New Research Supports Safety of Aspirin in Heart Failure

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Some research has raised concerns about the safety of aspirin for heart failure patients, but a new study, published in the Aug. 1 issue of JACC: Heart Failure, appears to offer some reassurance.

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