August 2017 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for August 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Minimal Evidence for Electronic Communication Guidelines

THURSDAY, Aug. 31, 2017 (HealthDay News) -- Minimal evidence is available for guidelines for electronic communication between patients and providers, according to research published online Aug. 28 in the Journal of the American Medical Informatics Association.

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Higher Event Rate of T2DM in Polycystic Ovary Syndrome

THURSDAY, Aug. 31, 2017 (HealthDay News) -- Women with polycystic ovary syndrome (PCOS) have a higher event rate of type 2 diabetes (T2D), with diagnosis at a younger age, according to a study published online Aug. 29 in the Journal of Clinical Endocrinology & Metabolism.

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Proactive Approach Encouraged for Online Patient Reviews

WEDNESDAY, Aug. 30, 2017 (HealthDay News) -- Most patients are using online reviews as a first step to finding a new doctor, with 65 percent forming an opinion from reading one to six reviews, according to a report published in Medical Economics.

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Novel Genetic Variant in IGF2 Linked to Reduced T2DM Risk

TUESDAY, Aug. 29, 2017 (HealthDay News) -- A novel genetic variant has been identified in the IGF2 gene among a Latino population that is associated with reduced risk for type 2 diabetes (T2D), according to a study published online Aug. 24 in Diabetes.

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Options Available for Estrogen Depletion After Breast Cancer

TUESDAY, Aug. 29, 2017 (HealthDay News) -- Many non-hormone options and therapies are available for the treatment of estrogen-depletion symptoms in breast cancer survivors, and individualized treatment is important, according to a review published online Aug. 2 in the Journal of Clinical Endocrinology & Metabolism.

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Flame Retardants Associated With Reduced IVF Success

MONDAY, Aug. 28, 2017 (HealthDay News) -- Higher exposure to organophosphate flame retardants is associated with reduced success of in vitro fertilization, according to a study published online Aug. 25 in Environmental Health Perspectives.

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Fatty Acid Remodeling Seen in T2DM Remission Post Bariatric Sx

MONDAY, Aug. 28, 2017 (HealthDay News) -- Remission of type 2 diabetes (T2D) following biliopancreatic diversion with duodenal switch (DS) is associated with increased disposal of triglycerides (TG) and acylcarnitine production during lipid overload, according to a study published online Aug. 23 in Diabetes.

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Diacerein Reduces Mean Hemoglobin A1c Levels in T2DM

FRIDAY, Aug. 25, 2017 (HealthDay News) -- An immune-modulator anti-inflammatory drug, diacerein, reduces the mean hemoglobin A1c (HbA1c) levels in patients with type 2 diabetes, according to a study published online Aug. 17 in Diabetes Care.

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Patient Beliefs May Explain High Rate of Medicine Intake

THURSDAY, Aug. 24, 2017 (HealthDay News) -- Subjective norms and attitudes toward medicine consumption predict the intention and expectation to consume medicines, according to a study published online Aug. 19 in the Journal of Clinical Pharmacy and Therapeutics.

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No Increase in Acute Kidney Injury Risk for SGLT2 Users

THURSDAY, Aug. 24, 2017 (HealthDay News) -- The risk of acute kidney injury (AKI) is not increased for new sodium-glucose cotransporter-2 (SGLT2) inhibitor users, according to a study published online Aug. 21 in Diabetes Care.

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Collaborative Communication Could Improve HTN Rx Adherence

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Health care providers can help boost patient adherence to antihypertensive medications by communicating more collaboratively with patients, and including discussion of socioeconomic challenges, according to a study published online Aug. 22 in Circulation: Cardiovascular Quality and Outcomes.

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Once-Yearly Counseling Tied to More Physical Activity in T2DM

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Theoretical and practical once-yearly counseling for three years is associated with increased physical activity (PA) and reduced sedentary (SED) time in patients with type 2 diabetes, according to a study published online Aug. 18 in Diabetes Care.

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Tablet Use Encourages Patients to Explore Diabetes Risk

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- The multispecialty San Bernardino Medical Group has replaced magazines with digital devices in waiting rooms, which can help patients learn about their risk of diabetes and take preventive action, according to a report published by the American Medical Association (AMA).

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Nurse-, System-Related Factors Analyzed in Wrong-Patient Events

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Greater focus is needed on correct identification processes in order to prevent wrong-patient medication administration incidents, and system supports for nurses are critical, according to a study published online Aug. 17 in the Journal of Clinical Nursing.

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Five Prebariatric Subtypes Identified With Specific Profiles

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Five prebariatric subtypes have been identified with specific self-control, emotional dysregulation, and disinhibited eating behavior profiles, according to research published online Aug. 16 in the International Journal of Eating Disorders.

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In T2D, Glycemic Control Up With Continuous Glucose Monitoring

TUESDAY, Aug. 22, 2017 (HealthDay News) -- Adults with type 2 diabetes receiving multiple daily insulin injections randomized to continuous glucose monitoring (CGM) have improved glycemic control versus usual care, according to a study published online Aug. 22 in the Annals of Internal Medicine.

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Many Parents Would Support Transgender Teen's Transition

TUESDAY, Aug. 22, 2017 (HealthDay News) -- More than half of U.S. adults surveyed would be supportive if they had a teenage child who wanted to transition to the opposite gender, according to a Harris Poll commissioned by the American Osteopathic Association.

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Hours Worked Impacted by Kids for Female, Not Male Doctors

MONDAY, Aug. 21, 2017 (HealthDay News) -- For women, but not men, in dual-physician couples, weekly hours worked are lower for those with versus those without children, according to a research letter published online Aug. 21 in JAMA Internal Medicine.

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Depression, Anxiety May Affect Bone Metabolism in Older Teens

MONDAY, Aug. 21, 2017 (HealthDay News) -- Major depressive disorder (MDD), generalized anxiety disorder (GAD), and selective serotonin reuptake inhibitor (SSRI) use are associated with bone metabolism in older adolescents and young adults, according to a study published online Aug. 16 in the Journal of Bone and Mineral Research.

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Secure Messaging Linked to Better Diabetes Management

MONDAY, Aug. 21, 2017 (HealthDay News) -- For patients with diabetes, use of secure messaging for medical advice is associated with better diabetes management, according to a study published online Aug. 14 in Diabetes Care.

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Radioiodine Therapy for Thyroid Cancer Doesn't Up Stroke Risk

FRIDAY, Aug. 18, 2017 (HealthDay News) -- Radioiodine (I-131) therapy for thyroid cancer is not associated with increased risk of stroke, according to a study published online Aug. 16 in Head & Neck.

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Studies Often Fail to Include Info on T2DM Medication Adherence

FRIDAY, Aug. 18, 2017 (HealthDay News) -- Studies often fail to include information on outcomes by medication adherence in type 2 diabetes, according to research published online Aug. 11 in Diabetes Care.

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Intensive Blood Pressure Tx Aids Those With Prediabetes

THURSDAY, Aug. 17, 2017 (HealthDay News) -- The beneficial effects of intensive systolic blood pressure (SBP) treatment are similar among those with prediabetes and fasting normoglycemia, according to a study published online Aug. 9 in Diabetes Care.

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Falling Insulin Requirement Linked to Placental Dysfunction

WEDNESDAY, Aug. 16, 2017 (HealthDay News) -- For pregnant women with pre-existing diabetes, falling insulin requirement (FIR) is associated with altered expression of placental antiangiogenic factors and preeclampsia, according to a study published online Aug. 10 in Diabetes Care.

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Lifestyle Intervention Only Offers Modest Benefit in Type 2 Diabetes

TUESDAY, Aug. 15, 2017 (HealthDay News) -- For adults with type 2 diabetes diagnosed for less than 10 years, a lifestyle intervention resulted in a beneficial change in glycemic control that did not reach the criterion for equivalence, according to a study published in the Aug. 15 issue of the Journal of the American Medical Association.

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Studies Used for FDA Approval of Device Changes Often Low Quality

TUESDAY, Aug. 15, 2017 (HealthDay News) -- Many studies used to support U.S. Food and Drug Administration approval of high-risk medical device modifications are not controlled; and efficacy of drugs granted accelerated approval is often confirmed three years after approval, according to two studies published in the Aug. 15 issue of the Journal of the American Medical Association.

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Specialist Access No Better With Adoption of Access Standards

TUESDAY, Aug. 15, 2017 (HealthDay News) -- Adoption of specialty access standards does not improve access to specialists, according to a study published online Aug. 14 in JAMA Internal Medicine.

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Exposure to Particulate Matter Linked to Metabolic Alterations

TUESDAY, Aug. 15, 2017 (HealthDay News) -- Exposure to particulate matter (PM) with aerodynamic diameters ≤2.5 µm is associated with metabolic alterations, according to a study published online Aug. 14 in Circulation.

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Sleep Duration Inversely Linked to Risk Markers of T2DM in Kids

TUESDAY, Aug. 15, 2017 (HealthDay News) -- There is an inverse correlation between sleep duration and risk markers of type 2 diabetes (T2D) in childhood, according to a study published online Aug. 15 in Pediatrics.

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Hyperglycemia May Cause Caries but Not Periodontal Disease

MONDAY, Aug. 14, 2017 (HealthDay News) -- For rodents with diabetes, periodontal inflammation may be derived from dental caries rather than periodontal disease (PD), according to a study published online Aug. 9 in Diabetes.

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Variation in Participation in Diabetes Self-Management Class

MONDAY, Aug. 14, 2017 (HealthDay News) -- There is considerable variation in nonparticipation in diabetes self-management classes, according to a study published online Aug. 3 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Taste, Calories Affect Metabolic Response to Sugared Beverages

FRIDAY, Aug. 11, 2017 (HealthDay News) -- There is a non-linear association between caloric load and reward, according to a study published online Aug. 10 in Current Biology.

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Subcutaneous Exendin Treats Post-Bariatric Hypoglycemia

FRIDAY, Aug. 11, 2017 (HealthDay News) -- Subcutaneous exendin (SC Ex-9) appears to be safe and effective in treating post-bariatric hypoglycemia (PBH), according to a study published online Aug. 4 in Diabetes, Obesity and Metabolism.

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Marrow Fat May Affect Bone Mass After Roux-en-Y Gastric Bypass

FRIDAY, Aug. 11, 2017 (HealthDay News) -- Glucose metabolism and weight are associated with marrow fat behavior, and marrow fat may determine bone mass after Roux-en-Y gastric bypass (RYGB), according to a study published online Aug. 9 in the Journal of Bone and Mineral Research.

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Team-Based Online Game May Improve Glycemic Control in T2D

THURSDAY, Aug. 10, 2017 (HealthDay News) -- Sustained and meaningful improvements in hemoglobin A1c (HbA1c) are seen with participation in a diabetes self-management education (DSME) game, according to a study published online Aug. 8 in Diabetes Care.

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Peptide Immunotx Well Tolerated in New-Onset Type 1 Diabetes

WEDNESDAY, Aug. 9, 2017 (HealthDay News) -- For patients newly diagnosed with type 1 diabetes, proinsulin peptide immunotherapy is safe and does not accelerate β cell functional decline, according to a study published in the Aug. 9 issue of Science Translational Medicine.

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Characteristics of Diabetes in Infancy Explored

WEDNESDAY, Aug. 9, 2017 (HealthDay News) -- Diabetes in infancy has different characteristics depending on mutation subtype, and is associated with high frequency of diabetic ketoacidosis (DKA), according to a report published online Aug. 4 in Diabetes Care.

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Midlife Vascular Risk Factors Tied to Increased Risk of Dementia

WEDNESDAY, Aug. 9, 2017 (HealthDay News) -- Risk factors for dementia include black race, older age, and lower educational attainment, as well as midlife vascular risk factors such as smoking, diabetes, and hypertension, according to a study published online Aug. 7 in JAMA Neurology.

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Flatter Diurnal Cortisol Slopes Linked to Poorer Health Outcomes

MONDAY, Aug. 7, 2017 (HealthDay News) -- Flatter diurnal cortisol slopes correlate with poorer health in 10 of 12 subtypes of emotional and physical health outcomes examined, according to a review published in the September issue of Psychoneuroendocrinology.

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Guidance Provided for Preventing Practice Billing Errors

MONDAY, Aug. 7, 2017 (HealthDay News) -- Strategies can help to prevent medical practice billing errors, according to a report published in Medical Economics.

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Mortality Down Only for Gastric Bypass Patients With Diabetes

MONDAY, Aug. 7, 2017 (HealthDay News) -- Patients undergoing Roux-en-Y gastric bypass (RYGB) with diabetes have reduced mortality compared with matched controls, according to a study published online July 31 in Diabetes Care.

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Strong Religious Beliefs May Be Linked to Higher Weight

FRIDAY, Aug. 4, 2017 (HealthDay News) -- There is evidence of a significant association between religious affiliation and body weight, with religiosity being significantly associated with higher body weight, according to research published online Aug. 2 in Obesity Reviews.

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mAb Glucagon Receptor Blocker Suitable for Further Development

FRIDAY, Aug. 4, 2017 (HealthDay News) -- The glucagon receptor blocker REGN1193, a fully human monoclonal antibody, seems safe and tolerable enough for further development, according to a study published online July 28 in Diabetes, Obesity and Metabolism.

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Ipragliflozin Beneficial in T2DM Complicated by Liver Disease

THURSDAY, Aug. 3, 2017 (HealthDay News) -- For patients with type 2 diabetes and nonalcoholic fatty liver disease (NAFLD), ipragliflozin exerts beneficial effects on NAFLD and glycemic control, similar to pioglitazone, according to a study published online July 27 in Diabetes Care.

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Revenue Exceeds Expenditures for Many ABMS Member Boards

WEDNESDAY, Aug. 2, 2017 (HealthDay News) -- Overall revenue exceeds expenditures for many American Board of Medical Specialties (ABMS) member boards, according to a study published in the Aug. 1 issue of the Journal of the American Medical Association.

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Canagliflozin Delays Increase in Certain CV Biomarkers in T2DM

WEDNESDAY, Aug. 2, 2017 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), treatment with canagliflozin delays the increase in serum N-terminal pro-B type natriuretic peptide (NT-proBNP) and high-sensitivity troponin I (hsTnI) compared with placebo, according to a study published in the Aug. 8 issue of the Journal of the American College of Cardiology.

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Similar Defects ID'd for T2DM, Chronic Pancreatitis and Diabetes

WEDNESDAY, Aug. 2, 2017 (HealthDay News) -- Patients with type 2 diabetes and those with diabetes secondary to chronic pancreatitis have similarly impaired α-cell responses to oral glucose ingestion and hypoglycemia, according to a study published online July 27 in Diabetes Care.

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Diabetes Symptoms Appear to Spread Via Prion-Like Mechanism

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Amyloid polypeptide (IAPP) deposits in the pancreas may lead scientists to a better understanding of type 2 diabetes, according to research published online Aug. 1 in the Journal of Experimental Medicine.

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New Research Supports Safety of Aspirin in Heart Failure

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Some research has raised concerns about the safety of aspirin for heart failure patients, but a new study, published in the Aug. 1 issue of JACC: Heart Failure, appears to offer some reassurance.

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Poor Adherence to Self-Monitoring of Glucose in GDM

TUESDAY, Aug. 1, 2017 (HealthDay News) -- Only about 60 percent of women with newly diagnosed gestational diabetes mellitus (GDM) perform ≥80 percent of required self-monitoring of blood glucose (SMBG) tests, according to a study published online July 18 in Diabetes Care.

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