August 2016 Briefing - Internal Medicine

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for August 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Ebola Virus Lingers in Semen Longer Than Expected

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- Ebola virus stays present in semen longer than previously thought, and is more likely to be found in older men, according to a study published online Aug. 30 in The Lancet Global Health.

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Sexual Health Often Suffers in Younger Patients Post-MI

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- After an acute myocardial infarction (AMI), many younger adults experience sexual difficulties -- and women more so than men, according to research published online Aug. 31 in JAMA Cardiology.

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FDA Approves Biosimilar Drug Erelzi for Rheumatoid Arthritis

THURSDAY, Sept. 1, 2016 (HealthDay News) -- A new biological drug to treat rheumatoid arthritis and other inflammatory diseases has been approved by the U.S. Food and Drug Administration.

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ACA Is Helping More Americans Afford Prescriptions

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- Though a growing number of Americans are able to afford prescription medications, millions still have difficulty, according to a study published online Aug. 23 in the American Journal of Public Health.

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9/11 Responders May Be at Higher Risk for Early Dementia

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- Posttraumatic stress disorder (PTSD) experienced by many rescuers and other first responders of 9/11 now appears linked to cognitive impairment and dementia, according to a report published online Aug. 18 in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

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First Case of Zika-Associated Sensory Polyneuropathy Reported

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- In a case report published online Aug. 21 in the Journal of Neurological Sciences, researchers confirm the first case of Zika-associated sensory polyneuropathy in an adult male.

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Retinoic Acid May Help Prevent, Treat Colorectal Cancer

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- Retinoic acid might have a role in suppressing colorectal cancer (CRC), according to experimental research published online Aug. 30 in Immunity.

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Optimism, Cynical Hostility Influence Fall Risk in Women

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- Optimism is associated with a decreased fall risk and cynical hostility with an increased fall risk for women, according to a study published online Aug. 27 in the Journal of Bone and Mineral Research.

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Body Mass Index, Fat Percentage Predict Menses Resumption

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- For patients with a history of anorexia nervosa, both body mass index and fat percentage can predict resumption of the menstrual cycle, according to a study published online Aug. 29 in the International Journal of Eating Disorders.

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TBC1D4 Mutation Common in North American Inuit

WEDNESDAY, Aug. 31, 2016 (HealthDay News) -- More than one-quarter of Canadian and Alaskan Inuit have the TBC1D4 mutation resulting in elevated postprandial glucose, and those with prediabetes and type 2 diabetes have increased risk of remaining undiagnosed, according to a study published online Aug. 25 in Diabetes Care.

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Sacubitril-Valsartan Reasonably Cost-Effective in Heart Failure

TUESDAY, Aug. 30, 2016 (HealthDay News) -- For patients with heart failure with reduced ejection fraction, sacubitril-valsartan is cost-effective for reducing cardiovascular mortality and morbidity, according to a study published online Aug. 30 in the Annals of Internal Medicine.

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Caregiver Well-Being Linked to Quality of Cancer Patient Care

TUESDAY, Aug. 30, 2016 (HealthDay News) -- Informal caregiver well-being is associated with patient-perceived quality of care (QOC), according to a study published online Aug. 29 in the Journal of Clinical Oncology.

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Researchers Investigate Three Drugs That Might Fight Zika

TUESDAY, Aug. 30, 2016 (HealthDay News) -- Three already existing drugs may offer pregnant women and their developing fetuses protection against the damaging effects of Zika virus, according to a new multicenter study published online Aug. 29 in Nature Medicine.

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Many Cases of Depression in Adults Not Being Treated

TUESDAY, Aug. 30, 2016 (HealthDay News) -- Many American adults who suffer from depression aren't getting treatment, according to a study published online Aug. 29 in JAMA Internal Medicine.

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Maintaining Body Weight Linked to Reduced Costs in T2DM

TUESDAY, Aug. 30, 2016 (HealthDay News) -- For patients with type 2 diabetes, maintaining body weight is associated with a reduction in medical care costs, while weight gain is associated with variable cost increases depending on the hemoglobin A1C level, according to a study published online Aug. 25 in Diabetes Care.

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Older MI Survivors Have High Event Risk Over Long Term

TUESDAY, Aug. 30, 2016 (HealthDay News) -- Older myocardial infarction (MI) survivors have long-term elevated risks of mortality and cardiovascular events, according to a study published online Aug. 26 in Cardiovascular Therapeutics.

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Intranasal Steroids Underused in Chronic Rhinosinusitis

MONDAY, Aug. 29, 2016 (HealthDay News) -- For adult patients with chronic rhinosinusitis (CRS), topical intranasal steroid therapy is underused, with an overall rate of utilization of 20.1 per 100 patients, according to research published online Aug. 25 in JAMA Otolaryngology-Head & Neck Surgery.

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Many NCCN Guideline Authors Report Conflicts of Interest

MONDAY, Aug. 29, 2016 (HealthDay News) -- Many National Comprehensive Cancer Network (NCCN) guideline authors report financial conflicts of interest (FCOIs), according to a study published online Aug. 25 in JAMA Oncology.

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Adults With CVD Have Gaps in Secondhand Smoke Knowledge

MONDAY, Aug. 29, 2016 (HealthDay News) -- Low-income adults with cardiovascular disease have considerable gaps in knowledge relating to secondhand smoke (SHS), according to a study published online Aug. 25 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Nighttime Sleep Disturbance Common in Chronic Pain

MONDAY, Aug. 29, 2016 (HealthDay News) -- Individuals suffering from chronic pain frequently have nighttime sleep disturbance, and it might be exacerbated by opioid treatment, according to a study published online Aug. 22 in Anaesthesia.

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Ezetimibe Plus Rosuvastatin Bests Rosuvastatin Alone

MONDAY, Aug. 29, 2016 (HealthDay News) -- For patients with primary hypercholesterolemia, fixed-dose combination of ezetimibe plus rosuvastatin is more effective than rosuvastatin alone, according to a study published online Aug. 10 in Cardiovascular Therapeutics.

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Echo-LVMI Ups Risk Prediction for Cardiovascular Disease

MONDAY, Aug. 29, 2016 (HealthDay News) -- Left ventricular mass indexed to body size (LV mass index [echo-LMVI]) can improve cardiovascular disease (CVD) risk prediction in older adults, according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Delirium-Related Training Inadequate for ICU Staff

MONDAY, Aug. 29, 2016 (HealthDay News) -- Training related to delirium is inadequate for intensive care unit (ICU) health care professionals, according to a study published online Aug. 18 in the Journal of Clinical Nursing.

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No Impact of Medicaid Expansion on Hospital LOS, Mortality

FRIDAY, Aug. 26, 2016 (HealthDay News) -- State Medicaid expansion as part of the Affordable Care Act (ACA) is not associated with length of stay (LOS) or in-hospital mortality among general medicine patients, according to a study published online Aug. 18 in the Journal of Hospital Medicine.

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Patients Lacking Straight Answers on Safety of E-Cigarettes

FRIDAY, Aug. 26, 2016 (HealthDay News) -- Doctors disagree on the best way to answer patient questions about electronic cigarettes, according to a study published online Aug. 26 in the American Journal of Preventive Medicine.

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Heat Illness Risk Highest in Early Preseason College Football

FRIDAY, Aug. 26, 2016 (HealthDay News) -- College football players face greatest risk for exertional heat illness (EHI) during the start of preseason play, according to a study published online Aug. 9 in the Journal of Athletic Training.

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CDC: Zika Transmitted by Sex Partner With No Symptoms

FRIDAY, Aug. 26, 2016 (HealthDay News) -- U.S. health officials report that the Zika virus can be spread sexually even when a partner shows no signs of infection. The research was published in the Aug. 26 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Ultrasound Treatment Appears Promising for Essential Tremor

FRIDAY, Aug. 26, 2016 (HealthDay News) -- Patients with essential tremor may benefit from a new noninvasive ultrasound procedure, according to a report published in the Aug. 25 issue of the New England Journal of Medicine.

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CDC: Synthetic Fentanyl a Major Factor in Opioid Overdose Deaths

FRIDAY, Aug. 26, 2016 (HealthDay News) -- Deaths from overdoses of illicitly manufactured fentanyl have increased significantly in recent years, according to research published in the Aug. 26 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Gliclazide Has Lowest Risk of Hypoglycemia of Newer SUs

FRIDAY, Aug. 26, 2016 (HealthDay News) -- Of the newer generation sulfonylureas (SUs), gliclazide is associated with the lowest risk of hypoglycemia when added to metformin, according to a systematic review and meta-analysis published online Aug. 3 in the British Journal of Clinical Pharmacology.

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Coronary Artery Calcium Increased in Psoriasis Patients

FRIDAY, Aug. 26, 2016 (HealthDay News) -- Increased coronary artery calcium, indicative of asymptomatic coronary atherosclerosis, is apparent in patients with psoriasis, and similar to that seen in patients with type 2 diabetes, according to a study published online Aug. 24 in JAMA Dermatology.

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Major Depressive Disorder Ups Acute MI Risk in HIV-Infected

FRIDAY, Aug. 26, 2016 (HealthDay News) -- For HIV-infected adults, major depressive disorder (MDD) is associated with an increased risk of acute myocardial infarction (AMI), according to a study published online Aug. 24 in JAMA Cardiology.

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In-Hospital Mortality Up With Weekend Admission in NSTEMI

FRIDAY, Aug. 26, 2016 (HealthDay News) -- For patients with non-ST-segment elevation myocardial infarction (NSTEMI), weekend admission is associated with increased in-hospital mortality, according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Most Clinicians Report That Sleep Quality in ICU Is Poor

FRIDAY, Aug. 26, 2016 (HealthDay News) -- Most clinicians believe that sleep in the intensive care unit (ICU) is poor and that poor sleep adversely affects patient outcomes, according to a study published in the August issue of the Annals of the American Thoracic Society.

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Endurance-Exercise-Induced Impairments in Atrial Function

FRIDAY, Aug. 26, 2016 (HealthDay News) -- During endurance exercise, there is exercise-dose-dependent impairment in atrial function, according to a study published online Aug. 17 in JACC: Cardiovascular Imaging.

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Plain Radiography Can ID Changes in Gouty Tophi Size

FRIDAY, Aug. 26, 2016 (HealthDay News) -- For patients with tophaceous gout, plain radiography can assess response to hypouricemic treatment, according to a study published online Aug. 12 in the International Journal of Rheumatic Diseases.

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Diabetes, Insulin Resistance Adversely Affect LV Function

THURSDAY, Aug. 25, 2016 (HealthDay News) -- Early exposure to diabetes mellitus (DM) or higher insulin resistance (IR) has an adverse effect on left ventricular (LV) remodeling and function, according to research published online Aug. 17 in JACC: Cardiovascular Imaging.

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IARC: Absence of Excess Body Fat Lowers Risk of Many Cancers

THURSDAY, Aug. 25, 2016 (HealthDay News) -- Excess weight is linked to risk of developing at least eight types of cancer, according to a report published in the Aug. 25 issue of the New England Journal of Medicine.

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Cardiovascular Disease Risk Up in Late-Onset Asthma Patients

THURSDAY, Aug. 25, 2016 (HealthDay News) -- Late-onset asthma may increase risk for incident cardiovascular disease (CVD) events, according to a study published online Aug. 24 in the Journal of the American Heart Association.

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Circulating Biomarkers May Be Indicative of Stroke Risk

THURSDAY, Aug. 25, 2016 (HealthDay News) -- In the future, a simple blood test might gauge a patient's odds of incident ischemic stroke (IIS), according to a study published online Aug. 24 in Neurology.

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Cancer Replaces CVD As Leading Cause of Death in 22 States

THURSDAY, Aug. 25, 2016 (HealthDay News) -- The gap between heart disease and the second-leading cause of death, cancer, has been narrowing since 1968, according to an August data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Vonoprazan-Based Triple Tx Feasible for H. pylori

THURSDAY, Aug. 25, 2016 (HealthDay News) -- The potassium-competitive acid blocker vonoprazan-based triple therapy seems safe and effective compared with conventional proton pump inhibitor (PPI)-based triple therapy as first-line treatment against Helicobacter pylori, according to a study published online Aug. 17 in the Journal of Digestive Diseases.

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Obese Women Have Greater Adipose Stores of Vitamin D

THURSDAY, Aug. 25, 2016 (HealthDay News) -- Obese women have significantly greater total vitamin D stores than normal-weight women, although the pattern of distribution of the stores is similar, according to a study published online Aug. 20 in the Journal of Bone and Mineral Research.

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Steep Rise in U.S. Drug Prices Tied to Patent Monopolies

WEDNESDAY, Aug. 24, 2016 (HealthDay News) -- Prescription drug prices are skyrocketing in the United States due in large part to government regulations, according to a study published in the Aug. 23/30 issue of the Journal of the American Medical Association.

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CDC Urges Prevention, Early Recognition of Sepsis

WEDNESDAY, Aug. 24, 2016 (HealthDay News) -- Many cases of life-threatening sepsis could be recognized and treated long before they cause severe illness or death, according to an Aug. 23 Vital Signs report from the U.S. Centers for Disease Control and Prevention.

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A-Fib Tied to Adverse Outcomes in Patients Undergoing PCI

WEDNESDAY, Aug. 24, 2016 (HealthDay News) -- For patients undergoing percutaneous coronary intervention (PCI), atrial fibrillation (AF) is associated with in-hospital adverse outcomes, according to a study published in the Aug. 30 issue of the Journal of the American College of Cardiology.

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Review: Frailty Status May Predict Outcome After Cardiac Surgery

WEDNESDAY, Aug. 24, 2016 (HealthDay News) -- Frailty status may be able to predict outcome in older adults undergoing cardiac surgical procedures, although the quality of evidence is variable, according to a review published online Aug. 23 in the Annals of Internal Medicine.

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For Those With T1D, More Former Smokers in U.S. Than Europe

WEDNESDAY, Aug. 24, 2016 (HealthDay News) -- Among patients with type 1 diabetes (T1D), there are more former smokers in the United States than in Europe, according to research published online Aug. 16 in Diabetes Care.

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Two Variants ID Cardiovascular Effect of Intensive Glycemic Tx

WEDNESDAY, Aug. 24 2016 (HealthDay News) -- Two genetic variants predict the cardiovascular effect of intensive glycemic control in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, according to research published online Aug. 15 in Diabetes Care.

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Donor Fecal Microbiota Transplant Effective for C. difficile Infection

TUESDAY, Aug. 23, 2016 (HealthDay News) -- For patients with recurrent Clostridium difficile infection (CDI), donor fecal microbiota transplantation (FMT) is safe and more efficacious than autologous FMT, according to a study published online Aug. 23 in the Annals of Internal Medicine.

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Imaging Shows Zika-Linked Congenital Brain Abnormalities

TUESDAY, Aug. 23, 2016 (HealthDay News) -- Imaging is revealing a wide variety of brain defects, eye defects, hearing issues, and stunted growth in newborns whose mothers were infected with the Zika virus, according to the special report published online Aug. 23 in Radiology.

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Pudendal Nerve Entrapment Can Lead to Eating Disorder

TUESDAY, Aug. 23, 2016 (HealthDay News) -- Pudendal nerve entrapment (PNE) leading to avoidant/restrictive food intake disorder (ARFID) has been described in a case report published online Aug. 19 in the International Journal of Eating Disorders.

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Disease-Guided Approach Ups Specificity of Statin Treatment

TUESDAY, Aug. 23, 2016 (HealthDay News) -- A disease-guided approach to statin eligibility can improve treatment specificity, according to a study published in the Aug. 30 issue of the Journal of the American College of Cardiology.

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Metformin Linked to Increased Risk of Acute Dialysis in T2DM

TUESDAY, Aug. 23, 2016 (HealthDay News) -- For patients with type 2 diabetes, metformin is associated with about a 50 percent increase in the risk of acute dialysis compared to sulfonylureas, according to a study published online Aug. 18 in Diabetes, Obesity and Metabolism.

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Benefits, Harms of Breast Cancer Screening Vary With Risk, Density

TUESDAY, Aug. 23, 2016 (HealthDay News) -- For women aged 50 years and older, benefits and harms of breast cancer screening vary with risk and breast density for all screening intervals, according to a study published online Aug. 23 in the Annals of Internal Medicine.

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Testosterone Solution Found Safe, Effective for Hypogonadal Men

MONDAY, Aug. 22, 2016 (HealthDay News) -- Once-daily 2 percent testosterone solution (T-sol) is safe and effective for sex drive and energy in hypogonadal men, according to a study published online in The Journal of Urology.

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Slight Decline in U.S. Prevalence of Latent TB From 2000 to 2011

MONDAY, Aug. 22, 2016 (HealthDay News) -- From 2000 to 2011 there was a slight decline in the prevalence of latent tuberculosis infection (LTBI) in the United States, according to a study published in the Aug. 15 issue of the American Journal of Respiratory and Critical Care Medicine.

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ACA Has Increased Rx Drug Use, Cut Out-of-Pocket Spending

MONDAY, Aug. 22, 2016 (HealthDay News) -- The Affordable Care Act (ACA) has increased prescription use and reduced out-of-pocket spending, according to a report published online Aug. 17 in Health Affairs.

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Barrier-Specific Care Significantly Improves Glycemic Control

MONDAY, Aug. 22, 2016 (HealthDay News) -- For patients with type 2 diabetes, barrier categories to glycemic control include psychological/support, socioeconomic, and accessibility, and addressing these barriers improves glycemic control, according to a study published online Aug. 11 in Diabetes Care.

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Decision Regret Uncommon After Radical Prostatectomy, IMRT

MONDAY, Aug. 22, 2016 (HealthDay News) -- For patients with prostate cancer treated with radical prostatectomy (RP) and post-prostatectomy image-guided intensity-modulated radiotherapy (IG-IMRT), decision regret (DR) is uncommon and occurs more often after RP, according to research published online Aug. 16 in the Journal of Medical Imaging and Radiation Oncology.

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Albuminuria Linked to Higher Nighttime SBP in Hypertension

MONDAY, Aug. 22, 2016 (HealthDay News) -- For patients with hypertension, albuminuria is associated with higher nighttime systolic blood pressure (SBP), according to a study published online Aug. 11 in Diabetes Care.

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Right Ventricular Remodeling Seen in Olympic Athletes

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Right ventricular (RV) remodeling occurs in Olympic athletes, according to a study published online Aug. 17 in JACC: Cardiovascular Imaging.

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Post-Op Doctor Shopping for One in Four With Nephrolithiasis

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Postoperative doctor shopping occurs in about one-quarter of patients with nephrolithiasis undergoing ureteroscopy, according to research published in the September issue of The Journal of Urology.

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Five Local Zika Cases Now Confirmed in Miami Beach

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Florida Gov. Rick Scott confirmed on Friday that local transmission of the Zika virus has occurred in Miami Beach, with a total of five cases reported so far.

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Oily Fish Consumption May Ward Off Diabetic Retinopathy

FRIDAY, Aug. 19, 2016 (HealthDay News) -- For patients with diabetes, two servings of fatty fish a week may be enough to lower their risk of diabetic retinopathy, according to a study published online Aug. 18 in JAMA Ophthalmology.

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Coronary Heart Disease Risk Up in Patients With Gallstones

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Patients with history of gallstone disease may have a slightly increased risk of developing coronary heart disease (CHD), according to research published online Aug. 18 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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USPSTF Ruling Followed by Fall in Early Prostate Cancer Diagnoses

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Diagnoses of early prostate cancer continue to decline in the United States, following the U.S. Preventive Services Task Force recommendation against routine screening, according to a research letter published online Aug. 18 in JAMA Oncology.

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Cardiac Arrest In-Hospital Death Down in Teaching Hospitals

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Among patients with cardiac arrest (CA), teaching hospital status is associated with decreased in-hospital mortality, according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Antimicrobial Tx Duration Often Exceeds Recommendations

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Antimicrobials are often prescribed for a longer duration than recommended in guidelines, according to a study published online Aug. 16 in the Journal of Hospital Medicine.

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Research Offers Insight Into Zika Virus Transmission to Placenta

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Primary human placental macrophages, known as Hofbauer cells, and placental villous fibroblasts are susceptible to infection by Zika virus, according to research published online Aug. 18 in JCI Insight.

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Both Concomitant, Sequential Treatment Effective for H. pylori

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Both concomitant therapy and sequential therapy achieve high eradication rates as the first-line therapy for Helicobacter pylori in areas with high rates of clarithromycin resistance, according to a study published online Aug. 9 in the Journal of Gastroenterology and Hepatology.

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Patients Still Risking Eye Damage With Poor Contact Lens Care

FRIDAY, Aug. 19, 2016 (HealthDay News) -- Unsafe use of contact lenses is triggering serious eye injuries for many Americans, according to research published in the Aug. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Calcium Supplements Tied to Dementia Risk in Older Women

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Taking calcium supplements to prevent osteoporosis may raise an older woman's risk of dementia, according to a study published online Aug. 17 in Neurology.

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Depression Often Seen in Patients Discharged From ICU

THURSDAY, Aug. 18, 2016 (HealthDay News) -- A significant number of former intensive care unit (ICU) patients experience depression, according to a review published in the September issue of Critical Care Medicine.

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Anemia Tied to Increased Mortality Risk Following Stroke

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Anemia may increase mortality risk for older stroke patients, according to research published online Aug. 17 in the Journal of the American Heart Association.

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Misclassification of Variants As Pathogenic in Black Americans

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Variants that have previously been considered causal in hypertrophic cardiomyopathy are often misclassified as pathogenic in patients with African or unspecified ancestry, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.

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Diabetes Linked to Increased CVD, Cancer, Other Mortality

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Diabetes is associated with increased mortality from cardiovascular disease, cancer, and noncardiovascular noncancer causes, according to a study published online Aug. 4 in Diabetes Care.

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Legal Issues Impact Delivery of Telehealth

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Telehealth technologies can allow delivery of high-quality care at a lower cost, especially in underserved areas, but there is currently no uniform legal approach to telehealth, hampering its provision, according to a Health Policy Brief published online Aug. 15 in Health Affairs.

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Obeticholic Acid Beneficial in Primary Biliary Cholangitis

THURSDAY, Aug. 18, 2016 (HealthDay News) -- For patients with primary biliary cholangitis, obeticholic acid is associated with a reduction in alkaline phosphatase levels, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.

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Full Med Adherence Reduces Costs for Patients With CVD

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Full adherence to guideline-recommended therapies is associated with a reduced rate of major adverse cardiovascular events (MACE) and cost savings, according to a study published in the Aug. 23 issue of the Journal of the American College of Cardiology.

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Sociodemographic Factors Affect Prostate CA Treatment Initiation

THURSDAY, Aug. 18, 2016 (HealthDay News) -- For men with low-risk prostate cancer undergoing active surveillance, sociodemographic factors are associated with initiation of active treatment, according to a study published in the September issue of The Journal of Urology.

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Duodenal Mucosal Resurfacing Cuts HbA1c in T2DM

THURSDAY, Aug. 18, 2016 (HealthDay News) -- Single-procedure duodenal mucosal resurfacing (DMR) is effective for reducing glycated hemoglobin (HbA1c) in patients with type 2 diabetes, according to a study published online Aug. 12 in Diabetes Care.

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Women Abused As Children Appear to Have Shorter Lifespans

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- Women who suffered physical or emotional abuse as children often die at a younger age than other women, according to research published online Aug. 17 in JAMA Psychiatry.

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β-Blockers Not Always Indicated for PCI Patients

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- Clinicians might be overprescribing β-blocker medications to heart patients, according to research published in the Aug. 22 issue of JACC: Cardiovascular Interventions.

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Early Intensification of Tx Speeds Attainment of A1C Goals

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- For patients newly diagnosed with type 2 diabetes, early intensification of therapy after metformin failure is associated with more rapid attainment of hemoglobin A1c (A1C) goals, according to a study published online Aug. 12 in Diabetes Care.

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PCSK9 Inhibitor Use Not Found to Be Cost-Effective

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- For patients with familial hypercholesterolemia (FH) or atherosclerotic cardiovascular disease (ASCVD), proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor use is not cost-effective, according to a study published in the Aug. 16 issue of the Journal of the American Medical Association.

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Physician Under-Recognition of Angina Often Occurs

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- Physicians frequently under-recognize angina in their patients with coronary artery disease, with under-recognition more likely for patients with heart failure and less-frequent angina, according to research published online Aug. 16 in Circulation: Cardiovascular Quality and Outcomes.

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Abaloparatide Reduces Fracture Risk in Women With Osteoporosis

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- In postmenopausal women with osteoporosis, an experimental drug appears to reduce the risk of bone fractures better than teriparatide or a placebo, according to a study published in the Aug. 16 issue of the Journal of the American Medical Association.

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Duration of Adult Obesity Affects Cancer Risk in Women

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- The longer a woman is overweight, the higher her risk of several cancers, according to a study published online Aug. 16 in PLOS Medicine.

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Residents Often Order Perceived Unnecessary Lab Tests

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- Residents frequently order perceived unnecessary inpatient laboratory tests, according to a study published online Aug. 13 in the Journal of Hospital Medicine.

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Physician-Perceived Frailty Tied to Warfarin Discontinuation

WEDNESDAY, Aug. 17, 2016 (HealthDay News) -- Physician-perceived frailty and low life expectancy are the main reasons for warfarin discontinuation in elderly patients, according to a study published online July 29 in the Journal of Thrombosis and Haemostasis.

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Large Trial Proposed to Compare HCTZ, Chlorthalidone

TUESDAY, Aug. 16, 2016 (HealthDay News) -- A large randomized trial is being developed to compare the effectiveness of hydrochlorothiazide with chlorthalidone in Veterans Affairs (VA) patients, according to an Ideas and Opinions piece published online Aug. 16 in the Annals of Internal Medicine.

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U.S. Female Doctors Reimbursed Significantly Less Than Males

TUESDAY, Aug. 16, 2016 (HealthDay News) -- Female doctors in the United States make much less than their male colleagues, according to a study published online Aug. 15 in the Postgraduate Medical Journal.

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Feeding Tube Use Down in Patients With Advanced Dementia

TUESDAY, Aug. 16, 2016 (HealthDay News) -- The use of feeding tubes for nursing home patients with advanced dementia is declining, according to a research letter published in the Aug. 16 issue of the Journal of the American Medical Association.

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More Evidence Paying Smokers to Quit May Work

TUESDAY, Aug. 16, 2016 (HealthDay News) -- Financial incentives may boost smoking cessation rates, according to a study published in the Aug. 23 issue of the Journal of the American College of Cardiology.

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Thrombocytopenia Up With Use of Phosphate-Buffered Tirofiban

TUESDAY, Aug. 16, 2016 (HealthDay News) -- For patients with acute coronary syndrome, phosphate-buffered tirofiban, but not citrate-buffered tirofiban, is associated with an increased risk of thrombocytopenia, according to a study published in the Aug. 22 issue of JACC: Cardiovascular Interventions.

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Antimicrobial Resistance to Carbapenems Increasing

TUESDAY, Aug. 16, 2016 (HealthDay News) -- Antimicrobial resistance to carbapenems has increased, and consumption of antibiotics, especially carbapenems, is associated with antimicrobial resistance of Pseudomonas aeruginosa, according to a study published online Aug. 11 in the Journal of Clinical Pharmacy and Therapeutics.

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DASH Diet May Be Beneficial for Gout Patients

TUESDAY, Aug. 16, 2016 (HealthDay News) -- The Dietary Approaches to Stop Hypertension (DASH) diet may offer a non-drug treatment for gout, according to a study published online Aug. 15 in Arthritis & Rheumatology.

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Low Evidence for PTRAS Versus Meds in Renal Artery Stenosis

TUESDAY, Aug. 16, 2016 (HealthDay News) -- For patients with atherosclerotic renal artery stenosis (ARAS), the strength of evidence for the relative benefits and harms of percutaneous transluminal renal angioplasty with stent placement (PTRAS) versus medical therapy alone is low, according to a review published online Aug. 16 in the Annals of Internal Medicine.

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DAPT Use Variable in Patients With A-Fib at Risk of Stroke

MONDAY, Aug. 15, 2016 (HealthDay News) -- For patients with atrial fibrillation at moderate to high risk of stroke, dual antiplatelet therapy (DAPT) use is variable among those undergoing percutaneous coronary intervention (PCI), according to a study published in the Aug. 22 issue of JACC: Cardiovascular Interventions.

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Cancer Now Leading Cause of Death in Some European Nations

MONDAY, Aug. 15, 2016 (HealthDay News) -- Cancer has overtaken cardiovascular disease (CVD) as the leading cause of death in 12 European countries, according to a study published online Aug. 14 in the European Heart Journal.

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Physical Function Tied to Clinical, Subclinical Neurological Disease

MONDAY, Aug. 15, 2016 (HealthDay News) -- Physical function is associated with clinical and subclinical brain disease, according to a study published online Aug. 8 in the Journal of Alzheimer's Disease.

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Interferon-Free, Tailored Tx Beneficial in HCV-Associated MC

MONDAY, Aug. 15, 2016 (HealthDay News) -- Interferon-free direct-acting antiviral (DAA) therapy is beneficial for hepatitis C virus (HCV)-associated mixed cryoglobulinemia (MC) vasculitis, according to a study published online Aug. 2 in Hepatology.

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Arhalofenate Beats Allopurinol for Gout Flares

MONDAY, Aug. 15, 2016 (HealthDay News) -- Arhalofenate (800 mg) is safe and significantly decreases gout flares compared to allopurinol (300 mg), according to a study published online July 27 in Arthritis & Rheumatology.

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Unstable Vital Signs for About One in Five Hospital Discharges

MONDAY, Aug. 15, 2016 (HealthDay News) -- Among adults with a hospitalization, vital sign instability on discharge is associated with increased risk of 30-day mortality and readmission, according to a study published online Aug. 8 in the Journal of General Internal Medicine.

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Liraglutide Added to Capped Insulin Reduces Hemoglobin A1c

MONDAY, Aug. 15, 2016 (HealthDay News) -- Liraglutide added to capped insulin is associated with reductions in glycated hemoglobin (HbA1c), body weight, and insulin requirements, according to a study published online Aug. 4 in Diabetes Care.

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Virtual Reality Component Reduces Risk of Falls in Elderly

FRIDAY, Aug. 12, 2016 (HealthDay News) -- For older adults at risk of falls, the addition of non-immersive virtual reality (VR) to treadmill training reduces the incidence of falls, according to a study published online Aug. 11 in The Lancet.

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Review Links Anxiety Disorders to Risk of Cardiovascular Events

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Anxiety disorders are associated with a range of cardiovascular events, according to a meta-analysis published in the Aug. 15 issue of The American Journal of Cardiology.

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Greater Drop in Hemoglobin A1c With Empagliflozin + Metformin

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Twenty-four weeks of empagliflozin + metformin correlates with a significantly greater reduction in hemoglobin A1c (HbA1c) compared with once-daily empagliflozin or twice-daily metformin, according to a study published online Aug. 4 in Diabetes Care.

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M. pneumoniae Infection Linked to Guillain-Barré Syndrome

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Mycoplasma pneumoniae infection is associated with Guillain-Barré syndrome (GBS), according to a study published online Aug. 4 in the Annals of Neurology.

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Zika Virus Proteins NS4A, NS4B Associated With Microcephaly

FRIDAY, Aug. 12, 2016 (HealthDay News) -- The Zika virus contains 10 proteins, but only two -- NS4A and NS4B -- are linked to microcephaly, according to a study published online Aug. 11 in Cell Stem Cell.

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Considerable Health Care System Burden for Undiagnosed COPD

FRIDAY, Aug. 12, 2016 (HealthDay News) -- The overall health system burden of exacerbations in patients with undiagnosed chronic obstructive pulmonary disease (COPD) is considerable, according to a study published in the Aug. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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One-Third of Patients Don't Retain Important Warfarin Info

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Just over two-thirds of patients retain an "acceptable" amount of key information following warfarin counseling, according to a small study published online Aug. 6 in the Journal of Pharmacy Practice and Research.

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Rosacea Tied to Higher Risk of GI Diseases

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Rosacea is associated with increased risk of some gastrointestinal diseases, according to a study published online Aug. 8 in the British Journal of Dermatology.

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Hand Hygiene Program Improves Hygiene Compliance

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Implementation of a hand hygiene program can improve compliance with hand hygiene and reduce health-care-associated infections (HAIs), according to a study published online Aug. 10 in Emerging Infectious Diseases.

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Topical Iodine Can Cause Overestimation of Blood Glucose

FRIDAY, Aug. 12, 2016 (HealthDay News) -- Use of topical iodine can cause overestimation of blood glucose (BG) readings, according to a case report published online Aug. 8 in the Journal of Clinical Pharmacy and Therapeutics.

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Grapefruit-Midazolam Interaction Varies With Juice Characteristics

FRIDAY, Aug. 12, 2016 (HealthDay News) -- The interaction between grapefruit juice and midazolam varies based on grapefruit juice-related characteristics such as the amount of furanocoumarin, according to a study published online Aug. 9 in the Journal of Clinical Pharmacology.

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2013 Saw 1.7 Million Home Visits From Primary Care Doctors

THURSDAY, Aug. 11, 2016 (HealthDay News) -- In 2013, about 5,000 primary care providers made about 1.7 million home-based medical visits, according to research published in the August issue of Health Affairs.

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Tx Response No Different for Migalastat, Placebo in Fabry's

THURSDAY, Aug. 11, 2016 (HealthDay News) -- For patients with Fabry's disease, the percentage of patients with response at six months does not differ for those treated with the oral pharmacologic chaperone migalastat or with placebo, according to a study published in the Aug. 11 issue of the New England Journal of Medicine.

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Stepwise Program Can Reduce Diabetes Incidence

THURSDAY, Aug. 11, 2016 (HealthDay News) -- A culturally-tailored stepwise diabetes prevention program can reduce incidence of diabetes among overweight/obese Asian Indian adults, according to a study published online Aug. 8 in Diabetes Care.

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CA-125 Strategy Cuts Death, Readmission in Heart Failure

THURSDAY, Aug. 11, 2016 (HealthDay News) -- For patients discharged with acute heart failure (AHF), antigen carbohydrate 125-guided therapy (CA125-strategy) is associated with a significant reduction in the risk of one-year death or readmission for AHF, according to a study published online Aug. 10 in JACC: Heart Failure.

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About Half of Older ICU Survivors Have Functional Recovery

THURSDAY, Aug. 11, 2016 (HealthDay News) -- About half of older intensive care unit (ICU) survivors have functional recovery within six months, with higher body mass index and functional self-efficacy associated with recovery, according to a study published in the Aug. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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Resistant Hypertension Linked to Increased Risk of Sleep Apnea

THURSDAY, Aug. 11, 2016 (HealthDay News) -- Among adults with hypertension, resistant hypertension (RH) is associated with increased risk of sleep apnea, according to a study published online July 18 in Respirology.

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Risk of Post-Op Opioid Abuse Deemed Low for Elderly Patients

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- Opioid abuse arises in only a very small fraction -- less than half of 1 percent -- of cases involving surgical patients aged 65 or older, according to a research letter published online Aug. 10 in JAMA Surgery.

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Suicide Rate Increased in Patients With Serious Infections

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- Patients hospitalized for serious infections may face an increased risk of suicide, according to research published online Aug. 10 in JAMA Psychiatry.

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Florida Reports Four More Cases of Local Zika Infection in Miami

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- Four more cases of Zika infection that were likely spread through mosquito bites have been reported in the Miami area, bringing the total count of cases to 21, Florida Gov. Rick Scott said Tuesday.

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Many U.S. Hospitals Offer Language Services

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- Overall, 68.8 percent of hospitals offer language services, with the proportion increasing with level of need, according to research published in the August issue of Health Affairs.

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Zika May Be Responsible for Arthrogryposis in Newborns

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- The Zika virus may be the cause of joint deformities in the arms and legs of newborns (arthrogryposis), according to a report published online Aug. 9 in The BMJ.

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Counterfeit Alprazolam Cut With Fentanyl Can Be Fatal

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- At least one San Francisco-area individual died and eight more were treated in the emergency department in late 2015 after taking counterfeit alprazolam (Xanax) tablets that had been cut with fentanyl, according to a case report published online Aug. 8 in JAMA Internal Medicine.

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Cerebral Protection Device Aids Patients Undergoing TAVI

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- For patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI), use of a cerebral protection device is associated with a reduction in the frequency of ischemic cerebral lesions, according to a study published in the Aug. 9 issue of the Journal of the American Medical Association.

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Dermatopathology More Common in Crohn's Than Ulcerative Colitis

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- Cutaneous manifestations of inflammatory bowel disease (IBD) should be considered when reviewing unexplained skin lesions, particularly in patients with Crohn's disease (CD), according to research published online Aug. 6 in the Journal of Cutaneous Pathology.

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IV Immunoglobulin Use Up in Interstitial Lung Disease

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- Intravenous immunoglobulin (IVIg) is increasingly being used for interstitial lung disease (ILD), despite a lack of evidence for its use, according to research published online Aug. 2 in the Annals of the American Thoracic Society.

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Many Patients Don't Reach Target Dose of Atomoxetine

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- A considerable proportion of patients receiving atomoxetine (ATX), especially those receiving ATX monotherapy, do not reach the recommended dose of 80 mg/day (ATX ≥80), according to a study published online July 31 in CNS Neuroscience & Therapeutics.

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Review IDs Determinants of Physical Activity in Women

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- For women, positive and consistent determinants of moderate-to-vigorous physical activity (MVPA) include higher self-efficacy, self-rated health and intentions, and perceived behavioral control, according to a review published online July 28 in Obesity Reviews.

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Water-Based Ai Chi Program Beneficial in Fibromyalgia

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- A water-based Ai Chi program is associated with improvements in quality of life for women with fibromyalgia syndrome (FMS), according to a study published online July 26 in the International Journal of Rheumatic Diseases.

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No Recent Change in Prevalence of Diabetic Kidney Disease

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- From 1988 to 2014 there was no change in the overall prevalence of diabetic kidney disease, according to a study published in the Aug. 9 issue of the Journal of the American Medical Association.

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Modest Changes in Practice for High-Sensitivity TnT Reporting

WEDNESDAY, Aug. 10, 2016 (HealthDay News) -- For patients presenting to the emergency department with chest pain, high-sensitivity troponin T (hs-TnT) reporting is associated with modest changes in practice, according to a study published online Aug. 9 in Circulation: Cardiovascular Quality and Outcomes.

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Western Diet May Contribute to Dense Breasts

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Overweight and obese women who eat a Western diet may develop more dense breast tissue, possibly increasing their risk for breast cancer, according to research published in the September issue of Obstetrics and Gynecology.

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Addition of Dapagliflozin Improves Glycemia in T1DM

TUESDAY, Aug. 9, 2016 (HealthDay News) -- For patients with type 1 diabetes (T1D), the addition of dapagliflozin to insulin and liraglutide is associated with significant improvement in glycemia and weight loss, according to a study published online Aug. 4 in the Journal of Clinical Endocrinology & Metabolism .

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Low Initial Dose, No Refills Can Help Prevent Opioid Dependency

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Patients who are first-time users of opioids should be prescribed a small dose without refills to reduce the risk of long-term use and possible addiction, according to a study published online Aug. 2 in the Journal of General Internal Medicine.

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Many Americans Exposed to Toxic Chemicals in Drinking Water

TUESDAY, Aug. 9, 2016 (HealthDay News) -- The levels of polyfluoroalkyl and perfluoroalkyl substances (PFASs) in drinking water exceed government-recommended safety levels for at least six million people in the United States, according to a report published online Aug. 9 in Environmental Science & Technology Letters.

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Hydroxycitrate Promising for Kidney Stone Prevention

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Hydroxycitrate, a natural fruit extract available as a dietary supplement, may dissolve a key component of kidney stones, potentially offering a new prevention tool against the condition, according to a study published online Aug. 8 in Nature.

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Soy Isoflavones Beneficial in Polycystic Ovary Syndrome

TUESDAY, Aug. 9, 2016 (HealthDay News) -- For women with polycystic ovary syndrome (PCOS), soy isoflavones improve metabolic status, according to a study published online Aug. 4 in the Journal of Clinical Endocrinology & Metabolism.

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Contemporary ECG Criteria Cuts Costs of Screening Athletes

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Contemporary electrocardiographic (ECG) screening criteria can reduce the costs of screening of athletes, according to a study published in the Aug. 16 issue of the Journal of the American College of Cardiology.

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Elbasvir-Grazoprevir Effective for HCV With Opioid-Agonist Tx

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Elbasvir-grazoprevir is effective for patients with chronic hepatitis C virus (HCV) receiving opioid-agonist therapy (OAT), according to a study published online Aug. 9 in the Annals of Internal Medicine.

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Need for Medical Care Offers Chance to Aid Trafficking Victims

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Injuries and illness requiring medical care present an opportunity for health care professionals to provide assistance to trafficked persons, according to an article published online Aug. 9 in the Annals of Internal Medicine.

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Active Life Expectancy Varies for Older Blacks, Whites

TUESDAY, Aug. 9, 2016 (HealthDay News) -- Life expectancy has increased for older whites and blacks, but blacks, especially women, have a smaller percentage of remaining life spent active, according to a study published in the August issue of Health Affairs.

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ICU May Up Invasive Procedures, Costs, Without Mortality Benefit

MONDAY, Aug. 8, 2016 (HealthDay News) -- Hospitals with higher intensive care unit (ICU) utilization for four common conditions have greater use of invasive procedures and costs of hospitalization, but do not have improved hospital mortality, according to a study published online Aug. 8 in JAMA Internal Medicine.

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Many Still Prescribe Concomitant (Es)omeprazole, Clopidogrel

MONDAY, Aug. 8, 2016 (HealthDay News) -- Advice of regulatory authorities released in 2009 and 2010 regarding safety concerns for concomitant use of clopidogrel and certain proton pump inhibitors (PPIs) was partially followed, according to a study published in the August issue of Pharmacology Research & Perspectives.

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Hospital Study Adds to Evidence of CVR Risk Tied to Periodontitis

MONDAY, Aug. 8, 2016 (HealthDay News) -- Periodontitis is associated with increased incidence of cardiovascular disease (CVD) and all-cause mortality, according to a study published in the Aug. 15 issue of The American Journal of Cardiology.

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FDA Approves First Generic Version of Tamiflu

MONDAY, Aug. 8, 2016 (HealthDay News) -- The first generic version of the flu medication Tamiflu has been approved by the U.S. Food and Drug Administration.

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Couple Phone Intervention Ups Glycemic Control for High A1C

MONDAY, Aug. 8, 2016 (HealthDay News) -- A collaborative couples telephonic intervention is associated with significant improvement in hemoglobin A1c (A1C) levels, according to a study published online July in Diabetes Care.

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No Recent Increase in Prevalence of Chronic Kidney Disease in U.S.

FRIDAY, Aug. 5, 2016 (HealthDay News) -- Since the early 2000s there has been little increase in the prevalence of stage 3 and 4 chronic kidney disease (CKD) in the United States, according to a study published online Aug. 2 in the Annals of Internal Medicine.

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Nonsterile Gloves Don't Up Risk of Infection in Minor Skin Sx

FRIDAY, Aug. 5, 2016 (HealthDay News) -- For patients undergoing outpatient cutaneous surgical procedures, use of nonsterile gloves is not associated with increased risk for surgical site infection (SSI), according to a review and meta-analysis published online Aug. 3 in JAMA Dermatology.

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Lipid Fractions May Be Linked to Risk of CAD, Diabetes

FRIDAY, Aug. 5, 2016 (HealthDay News) -- Routinely measured lipid fractions may be associated with the risk of coronary artery disease (CAD) and diabetes, according to a study published online Aug. 3 in JAMA Cardiology.

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Animal Studies Show Path for Zika Virus Vaccine in Humans

FRIDAY, Aug. 5, 2016 (HealthDay News) -- Three vaccine platforms have demonstrated protective efficacy against Zika virus (ZIKV) challenge in rhesus monkeys, according to research published online Aug. 4 in Science.

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Statin Use Tied to Reduced Risk of Parkinson's in Diabetes

THURSDAY, Aug. 4, 2016 (HealthDay News) -- For patients with diabetes, statin use is associated with reduced incidence of Parkinson's disease (PD), according to a study published online July 29 in the Annals of Neurology.

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Soy Isoflavone May Improve Bone Health Post Menopause

THURSDAY, Aug. 4, 2016 (HealthDay News) -- For postmenopausal women, soy isoflavone supplementation is associated with improvement in bone health, according to a study published online July 28 in the Journal of Bone and Mineral Research.

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Lymphatic Filariasis Linked to Higher Risk of HIV Infection

THURSDAY, Aug. 4, 2016 (HealthDay News) -- Lymphatic filariasis, a chronic helminth disease elicited by Wuchereria bancrofti, is associated with increased incidence of HIV infection, according to a study published online Aug. 2 in The Lancet.

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'Microhospitals' Can Provide Quicker Access to Care

THURSDAY, Aug. 4, 2016 (HealthDay News) -- Some health care systems are opening tiny hospitals which provide comprehensive emergency services but may have fewer than a dozen inpatient beds, according to a report published by Kaiser Health News.

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Amish Farm Environment May Protect Children From Asthma

THURSDAY, Aug. 4, 2016 (HealthDay News) -- The Amish environment seems to provide protection against asthma and allergic sensitization, according to a study published in the Aug. 3 issue of the New England Journal of Medicine.

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Patient-Level Model Predicts In-Hospital Mortality in Acute MI

THURSDAY, Aug. 4, 2016 (HealthDay News) -- A parsimonious patient-level clinical risk model can predict in-hospital mortality for patients with acute myocardial infarction, according to a study published in the Aug. 9 issue of the Journal of the American College of Cardiology.

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Panel Size of 2,500 Patients Per Doc Not Feasible in Primary Care

THURSDAY, Aug. 4, 2016 (HealthDay News) -- An often quoted standard panel size of 2,500 patients per physician seems not to be appropriate for primary care, according to a study published in the July-August issue of the Journal of the American Board of Family Medicine.

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Increased Risk of Diabetes With Nonfunctional Adrenal Tumors

THURSDAY, Aug. 4, 2016 (HealthDay News) -- Patients with nonfunctional adrenal tumors (NFATs) have increased risk of diabetes compared to those without adrenal tumors, according to a study published online Aug. 2 in the Annals of Internal Medicine.

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Spending on Compounded Drugs Skyrocketing

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- Government spending on compounded drugs has skyrocketed, raising concerns of fraud and overbilling, according to a report published by Kaiser Health News.

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Sickle Cell Trait Doesn't Up Mortality Risk in U.S. Soldiers

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- Sickle cell trait is not associated with a higher risk of death than absence of the trait, but it is associated with a significantly increased risk of exertional rhabdomyolysis, according to a study published in the Aug. 4 issue of the New England Journal of Medicine.

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Opioid-Related Insurance Claims Rise 3,000 Percent

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- The number of private health insurance claims for Americans addicted to opioids and heroin rose 3,203 percent from 2007 to 2014, according to a Fair Health report.

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Third Dose of MMR Vaccine Can Help Control Mumps Outbreaks

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- A third dose of measles-mumps-rubella (MMR) vaccine is recommended in cases of mumps outbreak in which transmission is sustained despite high two-dose MMR coverage, according to research published in the July 29 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Standardized Cardiac Telemetry IDs Cardiac Rhythm Change

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- An off-site central monitoring unit (CMU) applying standardized cardiac telemetry is associated with detection and notification of cardiac rhythm and rate changes before emergency response team (ERT) activation, according to a study published in the Aug. 2 issue of the Journal of the American Medical Association.

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Vasopressin Doesn't Cut Kidney Failure-Free Days in Septic Shock

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- Among adults with septic shock, early use of vasopressin does not improve the number of kidney failure-free days versus norepinephrine, according to a study published in the Aug. 2 issue of the Journal of the American Medical Association.

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Mortality Up With Impaired Glucose Tolerance

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- Patients with impaired glucose tolerance (IGT) face an increased risk of mortality, with much of the increased risk of mortality associated with progression to type 2 diabetes, according to a study published online July 13 in Diabetes Care.

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Overweight/Obesity Up Incidence of Hand, Hip, Knee Osteoarthritis

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- The incidence of hand, hip, and knee osteoarthritis (OA) increases with overweight and obesity, particularly in the knee, according to a study published in the August issue of Arthritis & Rheumatology.

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House Dust Mite Immunotherapy Effective for Allergic Rhinitis

WEDNESDAY, Aug. 3, 2016 (HealthDay News) -- For patients with allergic rhinitis (AR), house dust mite (HDM) sublingual immunotherapy is effective and seems safe, according to a study published online July 29 in Allergy.

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USPSTF Recommends Against Screening for Genital Herpes

TUESDAY, Aug. 2, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus (HSV) infection in adolescents and adults who are asymptomatic, including pregnant women. These findings form the basis of a draft recommendation statement published online Aug. 2 by the USPSTF.

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Physician Reviews Approaches to Treating Opioid-Use Disorders

TUESDAY, Aug. 2, 2016 (HealthDay News) -- Different approaches to the treatment of opioid-use disorders are addressed in an article published in the July 28 issue of the New England Journal of Medicine.

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High Doses of Omega-3s May Help Healing After Acute MI

TUESDAY, Aug. 2, 2016 (HealthDay News) -- Acute myocardial infarction (AMI) patients who take high doses of omega-3 fatty acids for six months show improved heart function and less scarring, according to a study published in the Aug. 2 issue of Circulation.

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Liraglutide Not Beneficial in Advanced Heart Failure

TUESDAY, Aug. 2, 2016 (HealthDay News) -- Liraglutide (Victoza) doesn't appear to improve heart function in patients with advanced heart failure, according to a study published in the Aug. 2 issue of the Journal of the American Medical Association.

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Biosimilar and Reference TNF-α Inhibitors Comparable

TUESDAY, Aug. 2, 2016 (HealthDay News) -- Biosimilar and reference tumor necrosis factor-α inhibitors appear to be appropriately interchangeable, according to a review published online Aug. 2 in the Annals of Internal Medicine.

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Twin Study Questions Link Between Obesity, Heart Risk

TUESDAY, Aug. 2, 2016 (HealthDay News) -- A study of identical twins, published online Aug. 1 in JAMA Internal Medicine, suggests that obesity may not increase the risk of myocardial infarction (MI) or premature death.

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No Independent Link for Fatty Pancreas, T2DM

TUESDAY, Aug. 2, 2016 (HealthDay News) -- After adjustment for confounding variables, fatty pancreas is not associated with type 2 diabetes mellitus (T2DM), according to a study published online July 15 in Diabetes Care.

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Predictors ID'd for Switching to Active Tx in Prostate Cancer

TUESDAY, Aug. 2, 2016 (HealthDay News) -- For men with low-risk prostate cancer, factors such as ethnicity influence patient decision to pursue active treatment during active surveillance, according to a study published online in The Journal of Urology.

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Urinary Biomarkers Can Predict Response in Lupus Nephritis

TUESDAY, Aug. 2, 2016 (HealthDay News) -- Low abundance biomarker panels can predict lupus nephritis outcomes, according to research published online July 27 in Arthritis & Rheumatology.

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Bleeding Risk Up With Aspirin After Lower GI Bleeding

TUESDAY, Aug. 2, 2016 (HealthDay News) -- For patients with a history of lower gastrointestinal (GI) bleeding, continuation of aspirin is associated with increased risk of recurrent bleeding, but reduced risk of cardiovascular events and death, according to a study published in the August issue of Gastroenterology.

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Memories of Delusions in ICU Include Fact, Fiction

TUESDAY, Aug. 2, 2016 (HealthDay News) -- Memories of delusions in the intensive care unit are composed of a mixture of fact and fiction, and are not dependent on the presence of delirium, according to a study published online July 26 in the Journal of Clinical Nursing.

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High Animal Protein Intake Tied to Higher Risk of Early Mortality

MONDAY, Aug. 1, 2016 (HealthDay News) -- People who get more of their protein from plant sources have an overall lower mortality risk than those who consume more animal protein, according to research published online Aug. 1 in JAMA Internal Medicine.

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Locally-Transmitted Zika Infection Count in Miami Up to 14

MONDAY, Aug. 1, 2016 (HealthDay News) -- The number of local transmissions of the Zika virus in South Florida has apparently increased to 14, Gov. Rick Scott said Monday.

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August Designated National Immunization Awareness Month

MONDAY, Aug. 1, 2016 (HealthDay News) -- In order to remind adults of the importance of immunizations throughout life, August is being recognized as National Immunization Awareness Month, according to a report from the American College of Physicians (ACP).

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ASBS: Contralateral Prophylactic Mastectomy Discouraged

MONDAY, Aug. 1, 2016 (HealthDay News) -- Contralateral prophylactic mastectomy should generally be discouraged in average-risk women, whose chances of developing breast cancer in the healthy breast are only 0.1 to 0.6 percent a year, according to a new American Society of Breast Surgeons position statement published online July 28 in the Annals of Surgical Oncology.

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Increasing Prevalence of Obesity in Cancer Survivors

MONDAY, Aug. 1, 2016 (HealthDay News) -- From 1997 to 2014 the estimated rate of annual increase in obesity prevalence was higher for adults with a history of cancer, according to a study published online July 25 in the Journal of Clinical Oncology.

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Locked Doors May Not Prevent Inpatient Suicide, Absconding

MONDAY, Aug. 1, 2016 (HealthDay News) -- For patients in psychiatric wards, treatment on locked wards seems not to prevent suicide, suicide attempts, or absconding, according to a study published online July 28 in The Lancet Psychiatry.

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Hospitalizations for Heart Failure With Preserved EF Common

MONDAY, Aug. 1, 2016 (HealthDay News) -- Heart failure with preserved ejection fraction (HFpEF) is common among patients hospitalized with acute heart failure, and patients with HFpEF are older, more often female, and frequently have comorbidities, according to a study published in the June issue of The American Journal of Medicine.

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European Countries Implementing Cost-Sharing

MONDAY, Aug. 1, 2016 (HealthDay News) -- European health systems are requiring an increase in cost-sharing measures for patients 50 years of age and older, according to research published in the July issue of Health Affairs.

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