August 2015 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for August 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA Warns of Joint Pain Tied to DPP-4 Inhibitors

MONDAY, Aug. 31, 2015 (HealthDay News) -- Use of dipeptidyl peptidase-4 (DPP-4) inhibitors in type 2 diabetes is tied to severe joint pain in some patients, the U.S. Food and Drug Administration warned on Friday.

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Nonalbuminuric CKD Ups Cardiovascular Morbidity in T1DM

MONDAY, Aug. 31, 2015 (HealthDay News) -- Nonalbuminuric chronic kidney disease is associated with increased risk of cardiovascular disease and all-cause mortality, but not renal outcomes, in patients with type 1 diabetes, according to a study published online Aug. 26 in Diabetes Care.

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Osteonecrosis of Jaw Risk Highest for IV Bisphosphonate Use

MONDAY, Aug. 31, 2015 (HealthDay News) -- The risk of osteonecrosis of the jaw (ONJ) is highest in association with intravenous bisphosphonate use, according to a study published online Aug. 19 in the Journal of Bone and Mineral Research.

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Periodontal Disease Predicts CAC Progression in Type 1 Diabetes

MONDAY, Aug. 31, 2015 (HealthDay News) -- In patients with type 1 diabetes, but not those without diabetes, periodontal disease duration is an independent predictor of long-term progression of coronary artery calcium (CAC), according to a study published in the Sept. 15 issue of The American Journal of Cardiology.

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Growth Hormone May Benefit Bone Health in Older Women

FRIDAY, Aug. 28, 2015 (HealthDay News) -- Older women with osteoporosis may benefit from a few years on growth hormone, a new, small trial suggests. The results were reported online Aug. 27 in the Journal of Clinical Endocrinology & Metabolism.

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AMA: Ruling Makes It Easier for Insurers to Terminate Doctors

FRIDAY, Aug. 28, 2015 (HealthDay News) -- The outcome of a recent case regarding the termination of physicians by an insurance company following a dispute over the necessity of medical services provided has serious implications for physicians and their patients, according to a report published by the American Medical Association (AMA).

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Antibiotic Use Linked to Higher Type 2 Diabetes Risk

FRIDAY, Aug. 28, 2015 (HealthDay News) -- Taking antibiotics might increase the risk of developing type 2 diabetes, new research suggests. The study was published online Aug. 27 in the Journal of Clinical Endocrinology & Metabolism.

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Patient Satisfaction Up for Dulaglutide Treatment in T2DM

THURSDAY, Aug. 27, 2015 (HealthDay News) -- For patients with type 2 diabetes, treatment satisfaction is improved with once-weekly dulaglutide, according to a study published in the September issue of Diabetes, Obesity and Metabolism.

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Misdiagnosis of T2DM Reported in Patient With Hb Wayne

WEDNESDAY, Aug. 26, 2015 (HealthDay News) -- Type 2 diabetes can be misdiagnosed in patients with hemoglobin (Hb) Wayne, according to a case report published online Aug. 20 in Diabetes Care.

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CDC: Rates of Childhood Obesity Higher in U.S. Than Canada

WEDNESDAY, Aug. 26, 2015 (HealthDay News) -- About 17.5 percent of U.S. children aged 3 to 19 are obese, compared with 13 percent of Canadian children the same age, according to an August data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Too Few Blacks, Hispanics Pursuing Careers As Physicians

TUESDAY, Aug. 25, 2015 (HealthDay News) -- Too few members of certain minority groups are pursuing careers in U.S. medicine, resulting in a serious lack of diversity among general practitioners and specialists, according to a research letter published online Aug. 24 in JAMA Internal Medicine.

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Supportive Doctors Boost Patients' Weight-Loss Efforts

MONDAY, Aug. 24, 2015 (HealthDay News) -- Weight loss is more successful for obese patients who feel they have the most helpful doctors compared to those who feel their doctors are less helpful, according to a study published in the September issue of Patient Education & Counseling.

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Perfluorinated Alkylate Levels Up in Breastfed Infants

MONDAY, Aug. 24, 2015 (HealthDay News) -- New mothers may inadvertently pass industrial chemicals along to their infants through breastfeeding, which might lower the effectiveness of some childhood vaccinations, researchers report. The study was published online Aug. 20 in Environmental Science & Technology.

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Metformin Effects May Be Via Gut, Not Bloodstream

MONDAY, Aug. 24, 2015 (HealthDay News) -- Metformin may act via a predominantly lower bowel-mediated mechanism, according to research published online Aug. 18 in Diabetes Care.

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Vitamin D Tied to Fewer Falls in Homebound Seniors

FRIDAY, Aug. 21, 2015 (HealthDay News) -- Delivering vitamin D supplements to homebound seniors might help lower their risk of falls, according to a study published online Aug. 16 in the Journal of the American Geriatrics Society.

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Bulimia Nervosa Tied to Increased Risk of Type 2 Diabetes

FRIDAY, Aug. 21, 2015 (HealthDay News) -- Binge eating disorder (BED) and bulimia nervosa (BN) are associated with increased incidence and prevalence of type 2 diabetes (T2D), according to a study published in the September issue of the International Journal of Eating Disorders.

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Patient, Family Advisors Can Play Key Role in Practices

FRIDAY, Aug. 21, 2015 (HealthDay News) -- Practices can employ patient and family advisors in order to help them focus on patient-centered care needs, according to a report published by the American Medical Association (AMA).

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Long-Acting Analog Insulin Doesn't Up AMI Risk in T2DM

THURSDAY, Aug. 20, 2015 (HealthDay News) -- For patients with type 2 diabetes, the risk of acute myocardial infarction (AMI) is not significantly different for long-acting insulin analogs versus other basal insulin therapies, according to a study published online Aug. 17 in Diabetes, Obesity and Metabolism.

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Report Highlights Ways to Improve Physician Resilience

THURSDAY, Aug. 20, 2015 (HealthDay News) -- Strategies can be adopted for improving physician resilience and the ability to handle the challenges presented by patient care, according to a report published by the American Medical Association (AMA).

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Role of SNP Variant in FTO Explored in Obesity

WEDNESDAY, Aug. 19, 2015 (HealthDay News) -- A single nucleotide variant in the FTO obesity locus disrupts a conserved motif, which has obesity effects, according to a study published online Aug. 19 in the New England Journal of Medicine.

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Acetaminophen Falsely Elevates CGM Glucose Values

WEDNESDAY, Aug. 19, 2015 (HealthDay News) -- Acetaminophen falsely increases continuous glucose monitor (CGM) glucose values, according to an observation letter published online Aug. 12 in Diabetes Care.

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New Program Teaches Medical Students About Healthy Eating

WEDNESDAY, Aug. 19, 2015 (HealthDay News) -- West Virginia has introduced a program to teach medical students how to talk to patients about healthy eating, and deliver practical advice to engaged patients, according to a report published by the American Academy of Family Physicians.

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Liraglutide Linked to Weight Loss Over 56 Weeks in T2DM

TUESDAY, Aug. 18, 2015 (HealthDay News) -- For overweight or obese patients with type 2 diabetes, subcutaneous liraglutide (3.0 mg) results in more weight loss than placebo over 56 weeks, according to a study published in the Aug. 18 issue of the Journal of the American Medical Association.

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Serious Childhood Infection Tied to Metabolic Disease Later in Life

MONDAY, Aug. 17, 2015 (HealthDay News) -- Infection-related hospitalization (IRH) during childhood is independently associated with adverse adult metabolic variables, according to a study published online Aug. 17 in Pediatrics.

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Metabolic Changes With Metformin May Lower LDL-C

MONDAY, Aug. 17, 2015 (HealthDay News) -- The diabetes drug metformin changes metabolic profiles of three metabolites that may lower LDL cholesterol (LDL-C), according to a study published online Aug. 5 in Diabetes Care.

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Insulin Resistance Tied to Signs of Cognitive Decline in Women

FRIDAY, Aug. 14, 2015 (HealthDay News) -- A higher homeostatic model assessment-insulin resistance index (HOMA-IR) score may be an early marker for an increased risk of cognitive decline in women, according to a study published online Aug. 12 in Diabetologia.

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Earlier Oocyte Retrieval May Aid Older Women Undergoing IVF

FRIDAY, Aug. 14, 2015 (HealthDay News) -- Earlier oocyte retrieval can help avoid premature follicular luteinization in older women undergoing in vitro fertilization (IVF), according to a study published online Aug. 11 in the Journal of Endocrinology.

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Long-Term Insulin Pump Use Reduces Mortality in T1DM

FRIDAY, Aug. 14, 2015 (HealthDay News) -- For individuals with type 1 diabetes, long-term use of continuous subcutaneous insulin infusion (insulin pump therapy) is associated with reduced cardiovascular and all-cause mortality, according to a study published online June 22 in The BMJ.

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More Physicians Reporting Dissatisfaction With EHR Systems

THURSDAY, Aug. 13, 2015 (HealthDay News) -- More physicians report being dissatisfied or very dissatisfied with their electronic health record (EHR) system, compared with five years ago, according to a report published by the AmericanEHR Partners and the American Medical Association.

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Troponin T Predicts Cardio Events in T2DM Patients With Stable IHD

WEDNESDAY, Aug. 12, 2015 (HealthDay News) -- For patients with type 2 diabetes and stable ischemic heart disease, troponin T concentrations predict cardiovascular events, according to a study published in the Aug. 13 issue of the New England Journal of Medicine.

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Trans, but Not Saturated, Fats Up All-Cause Mortality

WEDNESDAY, Aug. 12, 2015 (HealthDay News) -- Trans fats, but not saturated fats, are associated with all-cause mortality, coronary heart disease (CHD), and CHD-associated mortality, according to a systematic review published online Aug. 11 in The BMJ.

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Increased Work Disability in Diabetes Due to Comorbidity

WEDNESDAY, Aug. 12, 2015 (HealthDay News) -- Among individuals with diabetes, the increased risk of work disability is mainly due to comorbid mental, musculoskeletal, and circulatory disorders, according to a study published online Aug. 6 in Diabetes Care.

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Low-Fat, Higher-Complex Carb Diet Aids Gestational Diabetes

TUESDAY, Aug. 11, 2015 (HealthDay News) -- A higher-complex carbohydrate/lower-fat (CHOICE) diet significantly improves gestational diabetes mellitus (GDM)-associated markers compared to the conventionally recommended low-carbohydrate/higher-fat (LC/CONV) diet, according to a small study published online July 29 in Diabetes Care.

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HAC Reduction Program Penalty Kicks in for FY2015

TUESDAY, Aug. 11, 2015 (HealthDay News) -- The latest Centers for Medicare & Medicaid Services (CMS) effort to reduce hospital-acquired conditions (HACs) is the HAC Reduction Program, according to an Aug. 6 health policy brief published in Health Affairs.

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Breakfast Intake Affects Glucose Regulation All Day in T2D

MONDAY, Aug. 10, 2015 (HealthDay News) -- Breakfast consumption influences glucose regulation throughout the day in patients with diabetes, according to a small study published online July 28 in Diabetes Care.

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In-Person Staff Meetings Are Valuable for Health Care Teams

MONDAY, Aug. 10, 2015 (HealthDay News) -- In-person staff meetings, which are not too short or too long and are held frequently, are valuable for health care team operation, according to an article published in Medical Economics.

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CDC: Younger Adults With Diabetes Lag in Seeking Eye Care

MONDAY, Aug. 10, 2015 (HealthDay News) -- Younger adults with diabetes are less likely to seek regular eye care, regardless of how long it has been since they were first diagnosed, according to a report published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Nature of β-Cell Failure Tied to Glycemic Response to GLP-1RA

MONDAY, Aug. 10, 2015 (HealthDay News) -- In patients with type 2 diabetes, characteristics and biomarkers of β-cell failure are associated with glycemic response to GLP-1 receptor agonist (GLP-1RA) therapy, according to a study published online Aug. 4 in Diabetes Care.

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Iodine Supplementation in Pregnancy Cost Saving in U.K.

MONDAY, Aug. 10, 2015 (HealthDay News) -- Iodine supplementation is potentially cost saving for pregnant women in the United Kingdom, according to a review published online Aug. 9 in The Lancet Diabetes & Endocrinology.

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Many Hospitals Being Penalized for 30-Day Readmissions

FRIDAY, Aug. 7, 2015 (HealthDay News) -- About half of the nation's hospitals are being penalized by Medicare for having patients return within a month of discharge, losing a combined $420 million, according to a report published by Kaiser Health.

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Exercise in Early Adolescence May Ward Off Diabetes Later On

FRIDAY, Aug. 7, 2015 (HealthDay News) -- High levels of physical activity during the early teen years might reduce the risk of diabetes later in life, according to a new study published online Aug. 6 in Diabetologia.

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In Thyroid CA Radioiodine Ablation, rhTSH Better for HRQoL

THURSDAY, Aug. 6, 2015 (HealthDay News) -- For patients with thyroid cancer, recombinant human thyroid-stimulating hormone (rhTSH) prevents the transient deterioration of health-related quality-of-life (HRQoL) seen with use of thyroid hormone withdrawal (THW) at 131I administration, according to a study published online Aug. 3 in the Journal of Clinical Oncology.

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Bariatric Surgery Benefits May Fade With Time

THURSDAY, Aug. 6, 2015 (HealthDay News) -- Although weight-loss surgery may produce initial dramatic weight loss and improve type 2 diabetes, a new study suggests that in the long run, many people regain weight and see their diabetes return. The report was published online Aug. 5 in JAMA Surgery.

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Bariatric Surgery May Lower Tolerance for Alcohol

WEDNESDAY, Aug. 5, 2015 (HealthDay News) -- Patients who undergo Roux-en-Y gastric bypass surgery are far less able to process alcohol after their procedure, a small, new study suggests. The research was reported online Aug. 5 in JAMA Surgery.

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No Quick Fix in Cardiac Fat Metabolism From Calorie Cuts

WEDNESDAY, Aug. 5, 2015 (HealthDay News) -- Seven-day caloric and saturated fat restriction was found to increase myocardial dietary fatty acid (DFA) partitioning in individuals with impaired glucose tolerance (IGT), according to research published online July 29 in Diabetes.

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Bone Health Benefits Lacking for Vitamin D Supplements

TUESDAY, Aug. 4, 2015 (HealthDay News) -- High doses of vitamin D do not appear to protect postmenopausal women from osteoporosis, according to research published online Aug. 3 in JAMA Internal Medicine.

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Lifestyle Intervention Cuts GDM Among High-Risk Women

TUESDAY, Aug. 4, 2015 (HealthDay News) -- A moderate lifestyle intervention can reduce the incidence of gestational diabetes mellitus (GDM) among high-risk pregnant women, according to a study published online July 29 in Diabetes Care.

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For Obese Women, Exercise Plus Phototherapy Beneficial

MONDAY, Aug. 3, 2015 (HealthDay News) -- Exercise training combined with phototherapy is associated with improvements in the metabolic profiles of obese women, according to a study published online July 29 in Lasers in Surgery and Medicine.

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Review: mHealth Text Messages Promote Medication Adherence

MONDAY, Aug. 3, 2015 (HealthDay News) -- Mobile health (mHealth) short message service text messages can improve medication adherence, according to a review published online July 27 in the Journal of Clinical Nursing.

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Standing More Can Benefit Cardiometabolic Health

MONDAY, Aug. 3, 2015 (HealthDay News) -- Sitting appears to be linked to increased blood glucose and cholesterol levels, but standing more helps improve all these measures, according to research published online July 31 in the European Heart Journal.

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