ASA: <50 Percent Stenosis in Some Acute Ischemic Strokes

Share this content:
ASA: &#60;50 Percent Stenosis in Some Acute Ischemic Strokes
ASA: <50 Percent Stenosis in Some Acute Ischemic Strokes

THURSDAY, Feb. 18, 2016 (HealthDay News) -- Some ischemic strokes are not being ascribed to large-artery atherosclerosis because of <50 percent stenosis, according to a letter to the editor published online Feb. 17 in JACC: Cardiovascular Imaging to coincide with the annual American Stroke Association's International Stroke Conference, held from Feb. 17 to 19 in Los Angeles.

Ajay Gupta, M.D., from the Weill Cornell Medical College in New York City, and colleagues used data from a prospective stroke registry to examine the correlation between non-stenosing, vulnerable large-artery plaque and ischemic stroke, focusing on stroke from cardioembolism, small-vessel occlusion, and undetermined cause. They included 109 eligible patients with acute brain infarction limited to the vascular territory of a single internal carotid artery (ICA), as confirmed on magnetic resonance imaging.

The researchers found that 20.2 percent of the patients had <50 percent ICA plaques with intraplaque high-intensity signal (IHIS) ipsilateral to the side of infarction, whereas 8.3 percent of patients had IHIS in <50 percent ICA plaque contralateral to the side of infarction (P = 0.01). Patients with cryptogenic stroke had a significantly higher proportion of IHIS in ICA plaques ipsilateral to the side of infarction (P < 0.001); this was not seen in patients with strokes from cardioembolism or small-vessel occlusion (P = 0.76 and 0.49, respectively).

"Some strokes from large-artery atherosclerosis are currently not being recognized as such because the plaque causes <50 percent stenosis," the authors write.

Full Text (subscription or payment may be required)
More Information

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

ASTRO: No Survival Benefit for Adding EBT to Brachytherapy

ASTRO: No Survival Benefit for Adding EBT to ...

Addition of external beam therapy doesn't improve five-year progression-free survival in prostate cancer

ASTRO: Fewer Side Effects With IMRT in Cervical, Endometrial CA

ASTRO: Fewer Side Effects With IMRT in Cervical, ...

Patients in conventional radiotherapy arm had more high-level adverse events than those in IMRT arm

Many Doctors Reluctant to Reveal Mental Health Issues

Many Doctors Reluctant to Reveal Mental Health Issues

Perceived stigma, fear of career repercussions hinder treatment, study suggests

is free, fast, and customized just for you!

Already a member?

Sign In Now »