ARVO: Latanoprost Halts Myopia Progression in Animal Study

Share this content:
ARVO: Latanoprost Halts Myopia Progression in Animal Study
ARVO: Latanoprost Halts Myopia Progression in Animal Study

FRIDAY, May 12, 2017 (HealthDay News) -- Daily topical latanoprost may help stop progression of myopia, offering a potential new treatment for the condition, according to an experimental study presented at the annual meeting of the Association for Research in Vision and Ophthalmology, held from May 7 to 11 in Baltimore.

Nevin El-Nimri, O.D., and Christine F. Wildsoet, O.D., Ph.D., from the University of California Berkeley, performed monocular form deprivation (FD) in young guinea pigs from age 14 days for 12 weeks. After the first week, FD eyes received daily topical latanoprost or vehicle (four each).

The researchers found that relative to vehicle treatment, latanoprost reduced intraocular pressure (IOP) and slowed myopia progression. There were changes in the mean interocular IOP differences from baseline values of −0.58 ± 0.94 mm Hg and −1.25 ± 1.1 mm Hg for vehicle and latanoprost to 0.56 ± 1.34 mm Hg and −7.11 ± 3.66 mm Hg, respectively. There were changes in the interocular optical axial length differences, from −0.01 ± 0.04 to 0.22 ± 0.13 mm Hg for vehicle and from −0.05 ± 0.06 to −0.01 ± 0.05 mm Hg for latanoprost. Compared with vehicle eyes, in latanoprost eyes the fluctuations in IOP appeared to be lower and less variable, although the difference was not significant.

"The results demonstrate that daily topical latanoprost is effective in both lowering IOP and slowing myopia progression in FD eyes of young guinea pigs," the authors write.

Press Release
More Information

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »