April 2017 Briefing - Pediatrics

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Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for April 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Enzyme Replacement Drug OK'd for Form of Batten Disease

FRIDAY, April 28, 2017 (HealthDay News) -- Brineura (cerliponase alfa) has been approved by the U.S. Food and Drug Administration to treat a specific form of Batten disease, a rare set of genetic disorders that typically begin between ages 2 and 4, the agency said in a news release.

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Rx Errors Up With Generic Propranolol for Hemangioma

FRIDAY, April 28, 2017 (HealthDay News) -- Physicians prescribing propranolol in a single concentration of 4.28 mg/mL for infantile hemangioma (IH) report fewer prescribing errors than those prescribing generic propranolol, according to a research letter published in the May issue of the Journal of the American Academy of Dermatology.

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Single-Payer Health System Bill Moves Forward in California

THURSDAY, April 27, 2017 (HealthDay News) -- A proposal to replace private insurance with government-funded health care for all moved forward in California on Wednesday as Democrats on the Senate Health Committee voted to advance the measure.

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Risk Factors in Six Areas Tied to Physician Burnout

THURSDAY, April 27, 2017 (HealthDay News) -- Physician burnout factors include control, whether there is time to deliver excellent care, and whether the workplace is fair, according to a presentation at the Medical Group Management Association/American Medical Association 2017 Collaborate in Practice Conference, held April 9 to 11 in Chicago.

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Clinician Awareness of Exercise Addiction May Be Lacking

THURSDAY, April 27, 2017 (HealthDay News) -- Health care professionals need to recognize exercise addiction and understand its risks, according to a practice pointer published online April 19 in the BMJ.

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EHR Documentation May Help in Harm Reduction Initiatives

THURSDAY, April 27, 2017 (HealthDay News) -- Electronic health record (EHR) documentation can be used to reduce preventable harm in hospitals, according to a study published online April 27 in Pediatrics.

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MTX + Adalimumab Beneficial in JIA-Associated Uveitis

THURSDAY, April 27, 2017 (HealthDay News) -- Treatment with adalimumab plus methotrexate is effective in children and adolescents with active juvenile idiopathic arthritis-associated (JIA-associated) uveitis, according to a study published online April 26 in the New England Journal of Medicine.

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Higher QT Interval After Energy Drink Consumption Vs. Caffeine

THURSDAY, April 27, 2017 (HealthDay News) -- Consumption of energy drinks is associated with significantly higher corrected QT interval and systolic blood pressure (BP) than consumption of caffeine alone, according to a study published online April 26 in the Journal of the American Heart Association.

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Pediatricians Missing Elevated Blood Lead Levels in U.S.

THURSDAY, April 27, 2017 (HealthDay News) -- Many children with a blood lead level ≥10 µg/dL (elevated blood lead level [EBLL]) are being missed by pediatric care providers, according to a study published online April 27 in Pediatrics.

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AAP Stresses Medical Home Best for Acute Health Concerns

WEDNESDAY, April 26, 2017 (HealthDay News) -- The medical home is the ideal location for children to receive care for acute, nonemergency health concerns, according to a policy statement published online April 24 in Pediatrics.

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Children With Suspected Child Abuse Present to Hospital Late

WEDNESDAY, April 26, 2017 (HealthDay News) -- Children with suspected child abuse (SCA) present late to the hospital, and most arrive at hospitals that are not designated pediatric-capable major trauma centers, according to a study published online April 24 in the Emergency Medicine Journal.

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Checklist for Family-Centered Rounds Deemed Beneficial

WEDNESDAY, April 26, 2017 (HealthDay News) -- Implementation of a family-centered rounds (FCR) checklist and associated provider training is associated with an increase in the number of FCR elements performed, according to a study published online April 25 in Pediatrics.

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Model Predicts Which Pediatric ER Patients Likely to Be Admitted

TUESDAY, April 25, 2017 (HealthDay News) -- A new model can accurately predict pediatric patient hospitalization early in the emergency department encounter by using data commonly available in electronic medical records, according to a study published online April 25 in Pediatrics.

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Primary Care Pediatrician Vital for Cleft Lip/Palate Care

TUESDAY, April 25, 2017 (HealthDay News) -- For children with cleft lip and/or cleft palate (CL/P), the primary care pediatrician has an important role, according to a clinical report published online April 24 in Pediatrics.

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Doctors Encouraged to Assess Driving Risks for T1DM Patients

MONDAY, April 24, 2017 (HealthDay News) -- New research offers a checklist that helps determine whether it is safe for patients with type 1 diabetes to drive. The findings were published online April 12 in Diabetes Care.

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More Risks on School Playgrounds Linked to Happier Children

MONDAY, April 24, 2017 (HealthDay News) -- Children from schools with greater risk and challenge in the playground environment report being happier at school and playing with more children, according to a study published online April 24 in Pediatrics.

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NYC to Raise Cigarette Prices to Highest in the United States

FRIDAY, April 21, 2017 (HealthDay News) -- A proposal to boost the base price of a pack of cigarettes from $10.50 to $13.00 would make cigarettes in New York City the most expensive in the country.

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FDA Warns Against Children Taking Codeine, Tramadol

FRIDAY, April 21, 2017 (HealthDay News) -- Children should not be given any medications containing codeine or tramadol due to risk of life-threatening breathing difficulties, the U.S. Food and Drug Administration warned Thursday.

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Next Seven Great Achievements in Pediatric Research Predicted

FRIDAY, April 21, 2017 (HealthDay News) -- The next seven great achievements in pediatric research are presented in an article published online April 21 in Pediatrics.

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More Wrong-Patient Orders in NICU Versus Non-NICU Ped Units

FRIDAY, April 21, 2017 (HealthDay News) -- The risk of wrong-patient orders is higher in the neonatal intensive care unit (NICU) versus non-NICU pediatric units, and the risk of errors can be reduced with interventions, according to a study published online April 21 in Pediatrics.

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Electronic Drug Administration Record App Cuts Errors

THURSDAY, April 20, 2017 (HealthDay News) -- Use of an electronic medication administration record (eMAR) application can reduce the rate of medication errors in medication administration recording (ME-MAR), according to a study published online April 18 in the Journal of Evaluation in Clinical Practice.

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Potential Benefits, Risks of OpenNotes Discussed

WEDNESDAY, April 19, 2017 (HealthDay News) -- The benefits of sharing notes with patients include improved patient engagement and empowerment, while potential risks may include more phone calls, questions, and increased documentation time, according to a report published in Medical Economics.

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Dexamethasone Found to Be of Little Benefit in Acute Sore Throat

WEDNESDAY, April 19, 2017 (HealthDay News) -- A single dose of oral dexamethasone only offers modest benefit in the treatment of acute sore throat, according a study published in the April 18 issue of the Journal of the American Medical Association.

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Researchers Warn of Epilepsy in Zika-Infected Infants

WEDNESDAY, April 19, 2017 (HealthDay News) -- Beyond its known links to birth defects and other issues, the Zika virus may also trigger cases of epilepsy in infants, according to a viewpoint piece published online April 17 in JAMA Neurology.

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Long-Term Eye Health at Risk in Infants Born With Zika Infection

TUESDAY, April 18, 2017 (HealthDay News) -- Zika virus may lead to lifelong vision impairment in affected infants, according to research published online April 13 in JAMA Ophthalmology.

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Link Between Antidepressant Use in Pregnancy, Autism Challenged

TUESDAY, April 18, 2017 (HealthDay News) -- Taking antidepressants during pregnancy doesn't appear to raise a child's risk of autism, once other factors that could influence the risk are taken into account, according to two studies published in the April 18 issue of the Journal of the American Medical Association.

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Marijuana Use Higher in Pregnant Teens Than Nonpregnant Peers

TUESDAY, April 18, 2017 (HealthDay News) -- More than twice as many pregnant 12- to 17-year-olds use marijuana as their nonpregnant peers, and significantly more use the drug than pregnant women in their 20s, according to a letter published online April 17 in the Annals of Internal Medicine.

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High-Volume NICUs See More Staff Burnout

TUESDAY, April 18, 2017 (HealthDay News) -- Staff burnout in neonatal intensive care units (NICUs) is most prevalent in units with high patient volume and electronic health records, according to a study published online April 18 in Pediatrics.

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Hypnosis Doesn't Improve Post-Op Anxiety, Pain in Children

TUESDAY, April 18, 2017 (HealthDay News) -- A short hypnosis session performed in the operating room prior to major surgery does not improve postoperative anxiety and pain levels among pediatric patients, according to a study published online April 12 in the Journal of Clinical Nursing.

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Doctors Need to Be Mindful of What They Post on Social Media

MONDAY, April 17, 2017 (HealthDay News) -- Young doctors often have unprofessional or offensive content on their Facebook profiles, according to a study published online April 9 in BJU International.

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Retail Medical Sites Expanding to Provide Primary Care

MONDAY, April 17, 2017 (HealthDay News) -- Pharmacy chains are continuing to develop primary care venues within their stores, according to an article published in Medical Economics.

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Web-Based Platform Better for Delivering Pre-Op Information

FRIDAY, April 14, 2017 (HealthDay News) -- Attaining preoperative information from an interactive web-based platform is better than conventional brochure material for children aged 3 to 12 years and their parents, according to a research report published online April 10 in Pediatric Anesthesia.

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Fast-Acting Insulin Aspart Ups Glycemic Control in T1DM

FRIDAY, April 14, 2017 (HealthDay News) -- Fast-acting insulin aspart improves glycemic control in type 1 diabetes, according to a study published online April 11 in Diabetes Care.

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Iodide Supplementation No Benefit for Preemies

FRIDAY, April 14, 2017 (HealthDay News) -- For preterm infants, iodide supplementation is not associated with neurodevelopmental benefit at age 2 years, according to a study published online April 14 in Pediatrics.

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Continuous Glucose Monitoring Improves Quality of Life in T1DM

THURSDAY, April 13, 2017 (HealthDay News) -- Continuous glucose monitoring (CGM) contributes to significant improvements in diabetes-specific quality of life (QOL) measures among adults with type 1 diabetes mellitus (T1DM), according to a study published online April 7 in Diabetes Care.

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Physicians Are Spending Half Their Time on Computer Tasks

WEDNESDAY, April 12, 2017 (HealthDay News) -- Physicians spend roughly as many hours on computer work as they do meeting with patients, according to a study published in the April issue of Health Affairs.

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Chronic Alarm Fatigue Key Determinant of Response Time

WEDNESDAY, April 12, 2017 (HealthDay News) -- Nurses are usually quick to react when alarms are urgent, but they're slower to respond at the end of the workday or when they are experiencing "chronic alarm fatigue," according to a study published online April 10 in JAMA Pediatrics.

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Deep Brain Stimulation Beneficial in Severe Tourette's

WEDNESDAY, April 12, 2017 (HealthDay News) -- Some young patients with severe cases of Tourette's syndrome (TS) may benefit from deep brain stimulation (DBS), according to a study published online April 7 in the Journal of Neurosurgery.

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Cross-Sex Hormones Appear to Be Safe for Transgender Teens

TUESDAY, April 11, 2017 (HealthDay News) -- Cross-sex hormones appear to be safe for transgender adolescents, according to a study published online April 6 in Pediatrics.

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Race Affects Obesity-Related Risk of Adolescent Hypertension

TUESDAY, April 11, 2017 (HealthDay News) -- Obese teenagers are at increased risk of hypertension, but the effects of those extra pounds may vary by race and ethnicity, according to a study published online April 10 in Pediatrics.

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Direct-Acting Antivirals Approved for Children 12+ With HCV

MONDAY, April 10, 2017 (HealthDay News) -- The U.S. Food and Drug Administration has approved two drugs to treat hepatitis C virus (HCV) infection in children aged 12 and older.

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Integrated E-Prescribing Can Cut Prescribing, Dispensing Errors

MONDAY, April 10, 2017 (HealthDay News) -- An integrated electronic medication prescribing (e-prescribing) and dispensing system can reduce prescribing and dispensing errors, according to a study published online March 30 in the Journal of Pharmacy Practice and Research.

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Fungal Lesions Can Mimic Neoplastic Growths on Tongue

MONDAY, April 10, 2017 (HealthDay News) -- Fungal lesions can mimic neoplastic growths on the tongue, according to a case report published online April 5 in Pediatrics.

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Antenatal Betamethasone Doesn't Impact Pediatric Bone Mass

FRIDAY, April 7, 2017 (HealthDay News) -- Exposure to repeat doses of antenatal betamethasone is not associated with alterations in bone mass in mid-childhood compared with a single course of glucocorticoids, according to a study published online April 7 in Pediatrics.

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CDC: Almost Half of U.S. Men, Women <60 Infected With HPV

THURSDAY, April 6, 2017 (HealthDay News) -- Nearly half of American men and women under 60 have a genital human papillomavirus (HPV) infection, according to an April data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Risk Adjustment, Reinsurance Transfer Offer Financial Benefit

THURSDAY, April 6, 2017 (HealthDay News) -- Risk adjustment and reinsurance transfer programs seem to have been effective for increasing revenues at the expense of claims costs, according to research published in the March issue of Health Affairs.

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Hydrocortisone Tx Doesn't Impair Neurodevelopment in Preemies

WEDNESDAY, April 5, 2017 (HealthDay News) -- For extremely preterm infants, early hydrocortisone therapy is not associated with neurodevelopmental impairment at age 2 years, according to a study published in the April 4 issue of the Journal of the American Medical Association.

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CDC: Birth Defects Seen in 1 in 10 U.S. Pregnancies Affected by Zika

WEDNESDAY, April 5, 2017 (HealthDay News) -- One in 10 pregnant U.S. women with confirmed Zika infection in 2016 had a baby with virus-related birth defects, according to research published in the April 4 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Increased Cancer Risk for Childhood Kidney Recipients

WEDNESDAY, April 5, 2017 (HealthDay News) -- Childhood kidney recipients have increased cancer risk, according to a study published online March 29 in the American Journal of Transplantation.

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Red Cell Distribution Width Predicts Surgical Complications

WEDNESDAY, April 5, 2017 (HealthDay News) -- In children undergoing adenotonsillectomy for sleep-disordered breathing, preoperative elevated red cell distribution width is associated with an increased risk of respiratory adverse events, according to research published online March 27 in Pediatric Anesthesia.

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New Antibiotic Tx Beneficial After Acute Lung Function Decline in CF

TUESDAY, April 4, 2017 (HealthDay News) -- New antibiotic therapy, especially inpatient treatment, is associated with greater likelihood of recovery after acute lung function decline in children with cystic fibrosis, according to a study published online March 21 in the Annals of the American Thoracic Society.

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Doctors Must Be Wary of HIPAA Violations With Online Reviews

TUESDAY, April 4, 2017 (HealthDay News) -- Physicians should be aware that responding to a negative health care review could potentially expose personal medical information, resulting in a Health Insurance Portability and Accountability Act (HIPAA) violation, according to an article published in Medical Economics.

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Maternal Overweight, Obesity May Increase Childhood Epilepsy

TUESDAY, April 4, 2017 (HealthDay News) -- The rates of childhood epilepsy increase with maternal overweight and obesity, according to a study published online April 3 in JAMA Neurology.

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Maternal Pertussis Vaccination Reduces Risk for Newborns

TUESDAY, April 4, 2017 (HealthDay News) -- Infants are far less likely to develop pertussis if their mother received a tetanus toxoid, reduced diphtheria toxoid, acellular pertussis (Tdap) booster vaccination while pregnant, according to research published online April 3 in Pediatrics.

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Physical Activity Independently Predicts Bone Strength in Teens

TUESDAY, April 4, 2017 (HealthDay News) -- Moderate-to-vigorous physical activity (MVPA) is an independent predictor of bone strength at the tibia and radius in adolescents, according to a study published online March 23 in the Journal of Bone and Mineral Research.

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1990 to 2015 Saw Decrease in Global Child, Adolescent Mortality

TUESDAY, April 4, 2017 (HealthDay News) -- From 1990 to 2015 there was a decrease in global child and adolescent mortality, according to a study published online April 3 in JAMA Pediatrics.

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Variation in Occupational Influenza Vaccination Coverage

TUESDAY, April 4, 2017 (HealthDay News) -- There is variation in influenza vaccination coverage by industry and occupation, including among health care personnel and other occupational groups who may have first priority to receive influenza vaccination during a pandemic (tier 1), according to a study published in the April 1 issue of the American Journal of Infection Control.

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Mylan Issues Voluntary Recall of Some EpiPen Auto-Injectors

MONDAY, April 3, 2017 (HealthDay News) -- Mylan, the maker of EpiPen, says it is recalling select lots of EpiPen and EpiPen Jr. due to a defect that might render it difficult to activate in an emergency.

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Use of Health Literacy Tools Can Promote Shared Decision Making

MONDAY, April 3, 2017 (HealthDay News) -- Use of health literacy tools is encouraged for facilitating shared decision making (SDM), according to an article published in the March issue of the AMA Journal of Ethics.

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Bidirectional Link for Anorexia Nervosa, Celiac Disease

MONDAY, April 3, 2017 (HealthDay News) -- There is a bidirectional association between anorexia nervosa (AN) diagnosis and celiac disease (CD) in women, according to a study published online April 3 in Pediatrics.

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Vaccination Tied to Reduced Risk of Flu-Linked Pediatric Death

MONDAY, April 3, 2017 (HealthDay News) -- Influenza vaccination is associated with reduced risk of laboratory-confirmed influenza-associated death in children, with overall vaccine effectiveness of 65 percent, according to research published online April 3 in Pediatrics.

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School Nurses Overwhelmed by Guidelines for Managing Obesity

MONDAY, April 3, 2017 (HealthDay News) -- Barriers to school nurse-led implementation of national guidelines for managing overweight and obesity in school health services have been identified, according to a study published online March 23 in the Journal of Clinical Nursing.

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Twenty-Five Food Categories Explain 70 Percent of Salt Intake

MONDAY, April 3, 2017 (HealthDay News) -- For U.S. persons, 70 percent of dietary sodium comes from 25 food categories, with bread the top contributor, according to research published in the March 31 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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