April 2017 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for April 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Meeting Organizers Overlooking Qualified Female Scientists

FRIDAY, April 28, 2017 (HealthDay News) -- Invited speakers at medical conferences tend to be disproportionately male, a disparity that can be addressed by actively preparing lists of potential speakers, according to a study published online April 18 in Nature Immunology.

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Exercise Reduces Weight Gain Effects in Those With FTO Gene

FRIDAY, April 28, 2017 (HealthDay News) -- Eleven novel adiposity variants have been identified after adjustment for physical activity (PA), and PA can reduce the weight-gaining effects of the FTO gene by about 30 percent, according to a meta-analysis published online April 27 in PLOS Genetics.

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Older Women Show Limited Understanding of Osteoporosis

FRIDAY, April 28, 2017 (HealthDay News) -- Many older women have low awareness about osteoporosis and its contribution to fracture risk and a lack of understanding about the benefits of osteoporosis pharmacotherapy, according to a study published April 19 in the Journal of the American Geriatrics Society.

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Routine Blood Tests Can Harm Patient Care

FRIDAY, April 28, 2017 (HealthDay News) -- Routine blood tests waste money and can damage patient care, according to an opinion piece published online April 27 in the BMJ.

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Algorithm Integrated Into App Forecasts Glucose Levels

FRIDAY, April 28, 2017 (HealthDay News) -- A mechanistic model based on Gaussian process models and data assimilation can produce a personalized, nutrition-based glucose forecast for individuals with type 2 diabetes, according to a study published online April 27 in PLOS Computational Biology.

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Three Anti-VEGF Treatments Effective for Diabetic Retinopathy

THURSDAY, April 27, 2017 (HealthDay News) -- Three anti-vascular endothelial growth factor (anti-VEGF) treatments are associated with low rates of diabetic retinopathy (DR) worsening, according to a study published online April 27 in JAMA Ophthalmology.

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Single-Payer Health System Bill Moves Forward in California

THURSDAY, April 27, 2017 (HealthDay News) -- A proposal to replace private insurance with government-funded health care for all moved forward in California on Wednesday as Democrats on the Senate Health Committee voted to advance the measure.

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Risk Factors in Six Areas Tied to Physician Burnout

THURSDAY, April 27, 2017 (HealthDay News) -- Physician burnout factors include control, whether there is time to deliver excellent care, and whether the workplace is fair, according to a presentation at the Medical Group Management Association/American Medical Association 2017 Collaborate in Practice Conference, held April 9 to 11 in Chicago.

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Postbiotic Could Lower Glucose, Inflammation in Obesity

WEDNESDAY, April 26, 2017 (HealthDay News) -- The bacterial cell wall-derived muramyl dipeptide (MDP) postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice, according to an experimental study published online April 20 in Cell Metabolism.

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Plasma Uric Acid Lowering Tied to Drop in Systolic BP in T1DM

WEDNESDAY, April 26, 2017 (HealthDay News) -- Lowering of plasma uric acid (PUA) with febuxostat (FBX) is associated with a modest reduction in systolic blood pressure (BP) in patients with type 1 diabetes mellitus (T1DM), according to a study published online April 13 in Diabetes.

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T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder

TUESDAY, April 25, 2017 (HealthDay News) -- A common missense variant in the gene encoding a component of the sulfonylurea receptor (ABCC8 p.A1369S), which promotes closure of the target channel of sulfonylurea therapy, mimicking the effects of therapy, is associated with reduced risk of type 2 diabetes and coronary heart disease, according to a study published online April 14 in Diabetes.

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Central Obesity Ups Mortality Across BMI Range

TUESDAY, April 25, 2017 (HealthDay News) -- Central obesity is associated with increased risk of mortality even in normal-weight individuals, according to a study published online April 24 in the Annals of Internal Medicine.

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Doctors Encouraged to Assess Driving Risks for T1DM Patients

MONDAY, April 24, 2017 (HealthDay News) -- New research offers a checklist that helps determine whether it is safe for patients with type 1 diabetes to drive. The findings were published online April 12 in Diabetes Care.

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Cycling To and From Work Linked Lower CVD, Mortality Risk

MONDAY, April 24, 2017 (HealthDay News) -- Biking to work may help lengthen lifespan, according to a study published online April 19 in The BMJ.

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Wearable Devices Increasingly Being Used to Record Health Data

FRIDAY, April 21, 2017 (HealthDay News) -- Wearable devices are increasingly being used by patients to record health care data, and the number is expected to grow, according to an article published in Medical Economics.

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Surgeon Volume Impacts Parathyroidectomy Outcomes

FRIDAY, April 21, 2017 (HealthDay News) -- Patients undergoing parathyroidectomy by high-volume surgeons have a lower rate of vocal cord paralysis compared to patients of low-volume surgeons, according to a study published online April 20 in JAMA Otolaryngology-Head & Neck Surgery.

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Early Glycemic Control With Metformin Cuts CVD Events

FRIDAY, April 21, 2017 (HealthDay News) -- For patients with type 2 diabetes who initiate metformin, early achievement of low hemoglobin A1c (HbA1c) is associated with a reduction in the subsequent risk of cardiovascular events or death, according to a study published online April 12 in Diabetes Care.

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Vertical Integration Linked to Reduction in Readmissions

THURSDAY, April 20, 2017 (HealthDay News) -- Vertical integration, merging health care providers of different levels into a single unit, is associated with a reduction in readmissions overall, although the positive effect is seen for a limited number of conditions, according to a study published in the May issue of Medical Care.

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Retinopathy Risk, HbA1c Should Guide Frequency of T1D Eye Care

THURSDAY, April 20, 2017 (HealthDay News) -- Patients with type 1 diabetes and low risk for diabetic retinopathy may need less frequent ophthalmologic screenings, while patients at high risk may need to be seen more often than once a year, according to a study published in the April 20 issue of the New England Journal of Medicine.

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Just Over Half of MI Patients Taking Statins As Recommended

THURSDAY, April 20, 2017 (HealthDay News) -- Many myocardial infarction patients aren't taking statins as recommended, according to a brief report published online April 19 in JAMA Cardiology.

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Electronic Drug Administration Record App Cuts Errors

THURSDAY, April 20, 2017 (HealthDay News) -- Use of an electronic medication administration record (eMAR) application can reduce the rate of medication errors in medication administration recording (ME-MAR), according to a study published online April 18 in the Journal of Evaluation in Clinical Practice.

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Nurse-Led Intervention Helps With Diabetes Control

THURSDAY, April 20, 2017 (HealthDay News) -- Nurse-led interventions including education and cognitive behavioral therapy can improve hemoglobin A1c (HbA1c) control, according to a study published online April 11 in the Journal of Evaluation in Clinical Practice.

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Hypertension May Positively Affect Ovarian Cancer Prognosis

WEDNESDAY, April 19, 2017 (HealthDay News) -- A woman's prognosis after an ovarian cancer diagnosis may be affected by a number of unexpected factors, according to a review published recently in Cancer Causes & Control.

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Potential Benefits, Risks of OpenNotes Discussed

WEDNESDAY, April 19, 2017 (HealthDay News) -- The benefits of sharing notes with patients include improved patient engagement and empowerment, while potential risks may include more phone calls, questions, and increased documentation time, according to a report published in Medical Economics.

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U-Shaped Correlation Between Body Mass Index, Mortality

WEDNESDAY, April 19, 2017 (HealthDay News) -- The correlation between body mass index (BMI) and mortality is U-shaped, with the optimal BMI for lowest mortality increasing with worsening diabetes status, according to a study published online April 11 in Diabetes Care.

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Review: Interventions Don't Promote Exercise in Rural Adults

WEDNESDAY, April 19, 2017 (HealthDay News) -- Interventions to promote physical activity (PA) among adults have no effect in rural communities, according to a review published online April 11 in Obesity Reviews.

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Differing Statin Guidelines Leave Many Clinicians Uncertain

TUESDAY, April 18, 2017 (HealthDay News) -- If all clinicians followed U.S. Preventive Services Task Force (USPSTF) guidelines for prescription of a statin, nine million fewer adults would be taking such medication versus adherence to the American College of Cardiology/American Heart Association recommendations, according to a study published in the April 18 issue of the Journal of the American Medical Association.

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Glucose Variation Doesn't Affect Microvascular Complications

TUESDAY, April 18, 2017 (HealthDay News) -- Measures of glycemic variability in type 1 diabetes, based on complete quarterly 7-point glucose profiles, fail to provide evidence that glycemic variability contributes to the risk of development or progression of microvascular complications beyond the influence of mean glucose levels, according to a study published online April 12 in Diabetes Care.

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Costs Up With Specialist As Predominant Provider of Care

TUESDAY, April 18, 2017 (HealthDay News) -- For older adults with multimorbidity, having a specialist as the predominant provider of care (PPC) is associated with higher spending and lower continuity of care, according to a study published online April 8 in the Journal of the American Geriatrics Society.

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Doctors Need to Be Mindful of What They Post on Social Media

MONDAY, April 17, 2017 (HealthDay News) -- Young doctors often have unprofessional or offensive content on their Facebook profiles, according to a study published online April 9 in BJU International.

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RUNX1 May Play Role in Proliferative Diabetic Retinopathy

MONDAY, April 17, 2017 (HealthDay News) -- The Runt-related transcription factor 1 (RUNX1) gene may play a role in human proliferative diabetic retinopathy (PDR), and upregulation may be a marker of aberrant retinal angiogenesis, according to a study published online April 11 in Diabetes.

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Moderate, High-Intensity Exercise Programs Show Similar Results

MONDAY, April 17, 2017 (HealthDay News) -- Short-term moderate-intensity to high-intensity interval training (HIIT) leads to modest body composition improvements in overweight and obese individuals, according to research published online April 11 in Obesity Reviews.

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Fast-Acting Insulin Aspart Ups Glycemic Control in T1DM

FRIDAY, April 14, 2017 (HealthDay News) -- Fast-acting insulin aspart improves glycemic control in type 1 diabetes, according to a study published online April 11 in Diabetes Care.

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AMA: Two Internet Tools Can Help Educate Patients

THURSDAY, April 13, 2017 (HealthDay News) -- Internet resources can be helpful for educating patients and include myhealthfinder, which offers personalized recommendations for preventive services and a diabetes prevention tool, according to a report from the American Medical Association.

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Accurate Diagnosis of Endocrine Hypertension Important

THURSDAY, April 13, 2017 (HealthDay News) -- An accurate diagnosis of endocrine hypertension allows clinicians to provide effective treatment, including a surgical cure or to achieve an optimal response with specific pharmacologic therapy, according to a scientific statement published online April 5 in Endocrine Reviews.

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Diabetes Continues to Be a Significant Public Health Burden

THURSDAY, April 13, 2017 (HealthDay News) -- The incidence of diabetes is increasing among young persons, although some progress is seen with mortality and incidence of cardiovascular outcomes among patients with the disease, according to research published in the April 13 issue of the New England Journal of Medicine.

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Continuous Glucose Monitoring Improves Quality of Life in T1DM

THURSDAY, April 13, 2017 (HealthDay News) -- Continuous glucose monitoring (CGM) contributes to significant improvements in diabetes-specific quality of life (QOL) measures among adults with type 1 diabetes mellitus (T1DM), according to a study published online April 7 in Diabetes Care.

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Physicians Are Spending Half Their Time on Computer Tasks

WEDNESDAY, April 12, 2017 (HealthDay News) -- Physicians spend roughly as many hours on computer work as they do meeting with patients, according to a study published in the April issue of Health Affairs.

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Midlife Vascular Risk Factors Associated With Elevated Amyloid

WEDNESDAY, April 12, 2017 (HealthDay News) -- Individuals with risk factors for cardiovascular disease and stroke in middle age are more likely to have elevated levels of amyloid, according to a study published in the April 11 issue of the Journal of the American Medical Association.

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Cross-Sex Hormones Appear to Be Safe for Transgender Teens

TUESDAY, April 11, 2017 (HealthDay News) -- Cross-sex hormones appear to be safe for transgender adolescents, according to a study published online April 6 in Pediatrics.

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AHA: Patients Lack Confidence in Managing Their Cholesterol

TUESDAY, April 11, 2017 (HealthDay News) -- Many patients report lack of confidence or knowledge in keeping cholesterol under control, a new American Heart Association survey shows.

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Metformin Use Does Not Increase Prostate Cancer Survival

TUESDAY, April 11, 2017 (HealthDay News) -- Metformin use in combination with docetaxel chemotherapy does not significantly improve survival in patients with diabetes and metastatic castration-resistant prostate cancer, according to a study published in the April issue of The Journal of Urology.

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Integrated E-Prescribing Can Cut Prescribing, Dispensing Errors

MONDAY, April 10, 2017 (HealthDay News) -- An integrated electronic medication prescribing (e-prescribing) and dispensing system can reduce prescribing and dispensing errors, according to a study published online March 30 in the Journal of Pharmacy Practice and Research.

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Insulin Resistance Predicts Later Cognitive Decline

MONDAY, April 10, 2017 (HealthDay News) -- Higher serum fasting insulin and insulin resistance predict poorer verbal fluency and a steeper decline in future verbal fluency, according to a study published online April 5 issue of Diabetes Care.

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MACRA Changes Government Approach to Doctor Payment

FRIDAY, April 7, 2017 (HealthDay News) -- Implementation of the Medicare Access and CHIP Reauthorization Act (MACRA) has made fundamental changes to the government's approach to physician payment, according to a March 27 policy brief published in Health Affairs.

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Continuous Subcutaneous Insulin Infusion Bests Injections in T2DM

FRIDAY, April 7, 2017 (HealthDay News) -- For patients with type 2 diabetes and hemoglobin A1c (HbA1c) >8 percent following multiple daily injections (MDI), continuous subcutaneous insulin infusion (CSII) is associated with a significantly greater reduction in HbA1c than MDI, according to a study published online April 4 in Diabetes, Obesity and Metabolism.

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Antenatal Betamethasone Doesn't Impact Pediatric Bone Mass

FRIDAY, April 7, 2017 (HealthDay News) -- Exposure to repeat doses of antenatal betamethasone is not associated with alterations in bone mass in mid-childhood compared with a single course of glucocorticoids, according to a study published online April 7 in Pediatrics.

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Thyroidectomy for Thyroid CA Up Post 2006 Mass. Health Reform

FRIDAY, April 7, 2017 (HealthDay News) -- Implementation of the 2006 Massachusetts health reform, which is a model for the Affordable Care Act, correlated with an increased rate of thyroidectomy for treating thyroid cancer, according to a study published online April 5 in JAMA Surgery.

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Prevalence of Metformin Use 0.7 Percent in Prediabetes

THURSDAY, April 6, 2017 (HealthDay News) -- For U.S. adults with prediabetes, the prevalence of metformin use is 0.7 percent, according to a study published online April 3 in Diabetes Care.

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Risk Adjustment, Reinsurance Transfer Offer Financial Benefit

THURSDAY, April 6, 2017 (HealthDay News) -- Risk adjustment and reinsurance transfer programs seem to have been effective for increasing revenues at the expense of claims costs, according to research published in the March issue of Health Affairs.

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No CVD Protection Seen With Monthly High-Dose Vitamin D

THURSDAY, April 6, 2017 (HealthDay News) -- Taking high doses of vitamin D once a month won't lower the risk for cardiovascular disease, according to a study published online April 5 in JAMA Cardiology.

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Second Opinion Yields Different Diagnosis for 1 in 5 Patients

WEDNESDAY, April 5, 2017 (HealthDay News) -- One-fifth of patients who sought a second opinion recently at a single academic medical center had received a different diagnosis from their primary care providers, according to a study published online April 4 in the Journal of Evaluation in Clinical Practice.

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Bone, Basal Metabolism Link Depends on Vitamin D Level

WEDNESDAY, April 5, 2017 (HealthDay News) -- For postmenopausal women with type 2 diabetes mellitus (T2DMPW), the correlation between bone metabolism and basal metabolism seems to be dependent on serum 25-hydroxyvitamin D (25[OH]D) levels, according to a study published online March 31 in the Journal of Diabetes Investigation.

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More Metabolic Abnormality Among Normal-Weight Minorities

WEDNESDAY, April 5, 2017 (HealthDay News) -- Racial/ethnic minority groups have a significantly higher prevalence of metabolic abnormality but normal weight (MAN) than whites, according to a study published online April 4 in the Annals of Internal Medicine.

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Small Dietary Changes Cut Water Use, Can Improve Health

WEDNESDAY, April 5, 2017 (HealthDay News) -- Modest changes in diet can address the projected reduction in the availability of freshwater for irrigation in India, and can improve diet-linked health outcomes, according to a study published in the April issue of The Lancet Planetary Health.

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Doctors Must Be Wary of HIPAA Violations With Online Reviews

TUESDAY, April 4, 2017 (HealthDay News) -- Physicians should be aware that responding to a negative health care review could potentially expose personal medical information, resulting in a Health Insurance Portability and Accountability Act (HIPAA) violation, according to an article published in Medical Economics.

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Physical Activity Independently Predicts Bone Strength in Teens

TUESDAY, April 4, 2017 (HealthDay News) -- Moderate-to-vigorous physical activity (MVPA) is an independent predictor of bone strength at the tibia and radius in adolescents, according to a study published online March 23 in the Journal of Bone and Mineral Research.

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Maximum BMI Over 16 Years Ups Risk of All-Cause Death

TUESDAY, April 4, 2017 (HealthDay News) -- Maximum body mass index (BMI) over 16 years of weight history is associated with increased risk of all-cause death, according to a study published online April 4 in the Annals of Internal Medicine.

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Variation in Occupational Influenza Vaccination Coverage

TUESDAY, April 4, 2017 (HealthDay News) -- There is variation in influenza vaccination coverage by industry and occupation, including among health care personnel and other occupational groups who may have first priority to receive influenza vaccination during a pandemic (tier 1), according to a study published in the April 1 issue of the American Journal of Infection Control.

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Use of Health Literacy Tools Can Promote Shared Decision Making

MONDAY, April 3, 2017 (HealthDay News) -- Use of health literacy tools is encouraged for facilitating shared decision making (SDM), according to an article published in the March issue of the AMA Journal of Ethics.

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