April 2016 Briefing - Family Practice

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Here are what the editors at HealthDay consider to be the most important developments in Family Practice for April 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Hearing Aids Linked to Stronger Scores on Mini-Mental Exam

FRIDAY, April 29, 2016 (HealthDay News) -- New research suggests that hearing aids might help prevent or slow the development of dementia in elderly people with hearing loss. The study was published online April 25 in the American Journal of Geriatric Psychiatry.

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Generic Crestor Approved by FDA

FRIDAY, April 29, 2016 (HealthDay News) -- The first generic version of Crestor (rosuvastatin calcium) tablets was approved Friday by the U.S. Food and Drug Administration.

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First Zika-Related Death in Puerto Rico Reported

FRIDAY, April 29, 2016 (HealthDay News) -- The first known Zika virus-linked death in Puerto Rico was announced Friday by officials of the U.S. territory.

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FDA Reconsidering Training for Doctors Prescribing Opioids

FRIDAY, April 29, 2016 (HealthDay News) -- Mandatory safety training for doctors who prescribe opioids is being reconsidered by the U.S. Food and Drug Administration.

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First Commercial Zika Test Approved by FDA

FRIDAY, April 29, 2016 (HealthDay News) -- The first commercial test to diagnose Zika virus was approved Thursday by the U.S. Food and Drug Administration.

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Wide Variation in Health Care Costs Across the U.S.

FRIDAY, April 29, 2016 (HealthDay News) -- Health care prices vary widely across the United States, even within the same state, according to a study published in the April issue of Health Affairs.

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Guidelines Developed for Management of Atopic Dermatitis

FRIDAY, April 29, 2016 (HealthDay News) -- Guidelines have been developed for the management of atopic dermatitis (AD). The guidelines were published online April 14 in The Journal of Dermatology.

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Acute Diverticulitis No Worse in Younger Patients

FRIDAY, April 29, 2016 (HealthDay News) -- Younger patients do not have worse clinical presentation of acute diverticulitis, according to a study published online April 23 in the Journal of Digestive Diseases.

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New Six-Item Scale Predicts Sleep Apnea in Children

FRIDAY, April 29, 2016 (HealthDay News) -- A newly developed six-question scale has good predictive utility for identifying obstructive sleep apnea (OSA) in children, according to a study published online April 25 in Pediatric Anesthesia.

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Yoga Tied to Small Improvements in QoL, Symptoms in Asthma

FRIDAY, April 29, 2016 (HealthDay News) -- For patients with asthma, yoga seems to lead to small improvements in quality of life and symptoms, according to a review published online April 27 in The Cochrane Library.

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Article Discusses Workplace Violence in Health Care

THURSDAY, April 28, 2016 (HealthDay News) -- There is a lack of data relating to the prevalence of workplace violence in health care and how to address it, according to a review article published in the April 28 issue of the New England Journal of Medicine.

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Rates of Acid Suppression Med Rx Still Too High in NICUs

THURSDAY, April 28, 2016 (HealthDay News) -- Despite reported risks, nearly one in four infants in neonatal intensive care units (NICUs) are given histamine-2 receptor antagonists or proton pump inhibitors, according to a study published April 27 in The Journal of Pediatrics.

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Rosacea Linked to Increased Risk of Dementia

THURSDAY, April 28, 2016 (HealthDay News) -- Rosacea may be linked to a higher risk for dementia, particularly Alzheimer's disease (AD), according to research published online April 28 in the Annals of Neurology.

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CDC: Births of Triplets, Quadruplets on Decline in U.S.

THURSDAY, April 28, 2016 (HealthDay News) -- Since 1998, births of three or more babies at once have fallen by more than 40 percent in the United States, according to a report from the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS) published in the April issue of the NCHS Data Brief.

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Research Finds Link Between Psoriasis, Obesity, T2DM

THURSDAY, April 28, 2016 (HealthDay News) -- Psoriasis may be linked to excess weight and type 2 diabetes, according to a study published online April 27 in JAMA Dermatology.

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Review: Type 2 Diabetes Linked to Hearing Impairment

THURSDAY, April 28, 2016 (HealthDay News) -- Type 2 diabetes may raise the risk of hearing loss, according to a review published recently in Current Diabetes Reports.

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Review Compares Metformin, OCPs for Teens With PCOS

THURSDAY, April 28, 2016 (HealthDay News) -- For adolescents with polycystic ovarian syndrome (PCOS), treatment with metformin and oral contraceptive pills can be beneficial, although evidence is limited, according to a review published online April 28 in Pediatrics.

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Preventive Topical Steroids Cut Atopic Dermatitis Severity

THURSDAY, April 28, 2016 (HealthDay News) -- Intermittent preventive administration of topical corticosteroids in children controls the severity of atopic dermatitis (AD), according to a study published online April 14 in the Journal of Dermatology.

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Some Primary Care Physician Finances Are Improving

WEDNESDAY, April 27, 2016 (HealthDay News) -- The financial outlook for primary care practices is improving, but not all practices are experiencing the same improvements, according to an article published in Medical Economics.

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Doctors Have a Only a Few Weeks Left to Review Financial Data

WEDNESDAY, April 27, 2016 (HealthDay News) -- Under the Physician Payments Sunshine Act, physicians have only a few weeks left to review and report disputes relating to their financial ties to drug and medical device manufacturers, according to the American Medical Association.

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Mindfulness Therapy May Help Ease Recurrent Depression

WEDNESDAY, April 27, 2016 (HealthDay News) -- Mindfulness-based cognitive therapy may help reduce the risk of repeated episodes of depression, according to a study published online April 27 in JAMA Psychiatry.

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U.S. Health Report Card Finds Racial, Ethnic Disparities Persist

WEDNESDAY, April 27, 2016 (HealthDay News) -- An update on Americans' health finds that racial and ethnic disparities persist, with significant gaps in obesity, cesarean births, and dental care. But advances have been made in some important areas, including infant mortality rates, women smokers, and numbers of uninsured, according to the new report from the U.S. Department of Health and Human Services.

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Atomoxetine Use Doesn't Up Suicide Risk in Children

WEDNESDAY, April 27, 2016 (HealthDay News) -- Treatment with the selective noradrenalin-reuptake-inhibitor atomoxetine is not associated with increased suicide risk compared with stimulant use in children and adolescents, according to a study published online April 26 in Pediatrics.

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Simvastatin/Ezetimibe Not Beneficial in Alopecia Areata

WEDNESDAY, April 27, 2016 (HealthDay News) -- Simvastatin/ezetimibe does not appear to be beneficial for severe alopecia areata (AA) in a sample of 20 patients, according to a letter to the editor published in the May issue of the Journal of the American Academy of Dermatology.

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FDA: Fluconazole Linked to Increased Miscarriage Risk

WEDNESDAY, April 27, 2016 (HealthDay News) -- Health care professionals should use caution when prescribing the oral antifungal drug fluconazole (Diflucan) during pregnancy because it may raise the risk of miscarriage, the U.S. Food and Drug Administration warns.

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Certain Nutraceuticals May Augment Antidepressant Effects

WEDNESDAY, April 27, 2016 (HealthDay News) -- Certain nutritional supplements may improve the effectiveness of antidepressants, according to research published online April 26 in The American Journal of Psychiatry.

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Severe Childhood Obesity Still on the Rise in the United States

TUESDAY, April 26, 2016 (HealthDay News) -- Examining national data from 1999 through 2014, researchers found that one-third of American children aged 2 to 19 were overweight, nearly one-quarter were obese, and more than 2 percent were severely obese. The report was published online April 25 in Obesity.

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Coronary Heart Disease Risk Up for Women Working Night Shifts

TUESDAY, April 26, 2016 (HealthDay News) -- Women who work rotating night shifts may face a slightly increased risk of coronary heart disease (CHD), according to a report published in the April 26 issue of the Journal of the American Medical Association.

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Influenza Vaccination Timing Appears to Affect Efficacy

TUESDAY, April 26, 2016 (HealthDay News) -- Influenza vaccination may be more effective when people receive it in the morning than in the afternoon, according to a study published online April 26 in Vaccine.

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Pharmacists Can Manage Some Chronic Conditions Effectively

TUESDAY, April 26, 2016 (HealthDay News) -- Pharmacists can do an effective job helping chronically ill patients manage their blood pressure, cholesterol, and blood glucose levels if they're allowed to direct patients' health care, according to an evidence review published online April 26 in the Annals of Internal Medicine.

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Detergent Packets a Growing Poison Danger to Children

TUESDAY, April 26, 2016 (HealthDay News) -- A growing number of small children are getting their hands and mouths on colorful detergent packets, with serious and sometimes fatal consequences, according to a report published online April 25 in Pediatrics.

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Higher Arsenic Levels Detected in Infants Fed Rice-Based Cereals

TUESDAY, April 26, 2016 (HealthDay News) -- Infants fed rice-based foods may have significantly higher inorganic arsenic concentrations in their urine than those who never eat rice, according to a report published online April 25 in JAMA Pediatrics.

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Saxagliptin, Sitagliptin Don't Up Hospitalized Heart Failure

TUESDAY, April 26, 2016 (HealthDay News) -- Use of saxagliptin or sitagliptin is not associated with increased risk of hospitalized heart failure (hHF) compared with other antihyperglycemic agents, according to a study published online April 26 in the Annals of Internal Medicine.

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Prevalence of Migraine Up in Patients With Cardiac Syndrome X

TUESDAY, April 26, 2016 (HealthDay News) -- The prevalence of migraine headache is elevated in patients with cardiac syndrome X (CSX) compared to patients with coronary artery disease or healthy controls, according to a research letter published in the May 3 issue of the Journal of the American College of Cardiology.

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Direct Primary Care Is Emerging Business Model

TUESDAY, April 26, 2016 (HealthDay News) -- Direct primary care, where doctors bypass insurance companies, is an emerging business model, according to an article published in The Boston Globe.

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Triple Therapy No Benefit for COPD Exacerbations

TUESDAY, April 26, 2016 (HealthDay News) -- The addition of tiotropium to long-acting β2-agonists (LABA) and/or inhaled corticosteroids (ICS) does not reduce chronic obstructive pulmonary disease (COPD) exacerbations compared to LABA/ICS alone, according to a study published online April 20 in the Journal of Clinical Pharmacology.

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A Doctor's View: EHRs Impair Physician-Patient Relationship

MONDAY, April 25, 2016 (HealthDay News) -- Electronic health records (EHRs) may be impairing the physician-patient relationship, according to an article published in Medical Economics.

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AAP: ALTE Now Termed 'Brief Resolved Unexplained Events'

MONDAY, April 25, 2016 (HealthDay News) -- The new term, "brief resolved unexplained events" (BRUE), replaces the previous term, "apparent life-threatening events" (ALTE), per an expert panel from the American Academy of Pediatrics (AAP). The new AAP clinical guideline was published online April 25 in Pediatrics.

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No Link for Smoking Cessation Meds, Mental Health Issues

MONDAY, April 25, 2016 (HealthDay News) -- Varenicline (Chantix) and bupropion (Wellbutrin) don't appear to raise the risk of mental health disorders such as depression, anxiety, and suicidal thoughts, according to a new study published online April 22 in The Lancet.

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Rapid-Onset Diabetes Described With Anti-PD-1 Treatment

MONDAY, April 25, 2016 (HealthDay News) -- In a case report published online April 11 in the Journal of Diabetes Investigation, researchers document rapid-onset insulin-dependent diabetes in an Asian patient undergoing treatment with anti-programmed cell death-1 (anti-PD-1) therapy.

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Alkali Eye Injuries Secondary to Airbag Deployment Reported

MONDAY, April 25, 2016 (HealthDay News) -- In a report published online April 15 in Clinical and Experimental Ophthalmology, two cases are presented of alkali eye injuries secondary to airbag deployment.

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Continued Aspirin Treatment Safe With Partial Nephrectomy

MONDAY, April 25, 2016 (HealthDay News) -- Continuing aspirin for chronic antiplatelet therapy is safe in patients undergoing laparoscopic partial nephrectomy, according to a study published in the April issue of The Journal of Urology.

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Poor Persistence/Adherence With Long-Term Topical AK Treatment

MONDAY, April 25, 2016 (HealthDay News) -- A considerable proportion of patients with actinic keratosis (AK) receiving long-term topical treatment have poor persistence or adherence, according to a study published online April 18 in the British Journal of Dermatology.

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Physicians Can Get Involved in Developing Payment Models

FRIDAY, April 22, 2016 (HealthDay News) -- Doctors can be involved in developing new payment models for their practices, according to the American Medical Association.

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CDC, OSHA Issue Guidance on Occupational Exposure to Zika

FRIDAY, April 22, 2016 (HealthDay News) -- Summer, mosquito season, and the threat of Zika virus transmission is approaching, and federal health experts on Friday issued guidelines to help protect American workers from infection.

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Heavy Cannabis Use in Teen Years Tied to Earlier Mortality

FRIDAY, April 22, 2016 (HealthDay News) -- Men who were heavy cannabis smokers in their teens may not live as long as those who did not use cannabis when they were young, according to a study published online April 22 in The American Journal of Psychiatry.

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CDC: Suicide Rate Up 24 Percent in the United States Since 1999

FRIDAY, April 22, 2016 (HealthDay News) -- Suicide rates in the United States rose 24 percent between 1999 and 2014, with young girls and middle-aged men accounting for the largest increases, according to an April data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Aromatase Inhibitors Won't Raise Odds of Most Fatal CVD Events

FRIDAY, April 22, 2016 (HealthDay News) -- Treatment with aromatase inhibitors doesn't raise the risk of the most fatal cardiovascular disease events among breast cancer survivors, according to research published online April 21 in JAMA Oncology.

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Anthracyclines May Not Trigger 'Chemo Brain'

FRIDAY, April 22, 2016 (HealthDay News) -- Anthracyclines are not related to "chemo brain," according to a research letter published online April 21 in JAMA Oncology.

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How One Health System Is Shifting From Volume to Value

FRIDAY, April 22, 2016 (HealthDay News) -- ACCESS Health System, which operates 36 health centers, is transitioning to a patient-centered, physician-friendly health system that provides a continuum of care to underserved populations, according to the American Medical Association (AMA).

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Lipid Tx Cuts Cardiovascular Risk with Type 1 Diabetes

FRIDAY, April 22, 2016 (HealthDay News) -- The risk of cardiovascular disease (CVD) and cardiovascular death is 22 to 44 percent lower among individuals with type 1 diabetes treated with lipid-lowering therapy (LLT), according to a study published online April 18 in Diabetes Care.

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Ideal BP in Elderly With Chronic Kidney Disease Unclear

FRIDAY, April 22, 2016 (HealthDay News) -- Age modifies the association between blood pressure (BP) and adverse cardiovascular and renal outcomes in elderly patients with chronic kidney disease (CKD), according to research published online April 21 in the Clinical Journal of the American Society of Nephrology.

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Stomach CA Risk Up With Alcohol, Processed Meat Consumption

THURSDAY, April 21, 2016 (HealthDay News) -- Alcohol, processed meats -- such as hot dogs, ham, and bacon -- and excess weight all may raise a person's risk of stomach cancer, according to a new review released by the American Institute for Cancer Research and the World Cancer Research Fund International.

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Preexisting Mental Distress Can Slow Concussion Recovery

THURSDAY, April 21, 2016 (HealthDay News) -- Athletes may take longer to recover after a concussion if they had psychosomatic symptoms before their head injury, according to a study published online April 20 in Neurology.

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Comorbidity Tied to Prostate Cancer Upgrading, Up Staging

FRIDAY, April 22, 2016 (HealthDay News) -- Comorbidity burden is strongly and independently associated with pathological upgrading/up staging in men with clinically low-risk prostate cancer, according to a study published in the April issue of The Journal of Urology.

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Interrupting Prolonged Sitting Beneficial in Type 2 Diabetes

THURSDAY, April 21, 2016 (HealthDay News) -- For patients with type 2 diabetes (T2D), interrupting prolonged sitting with three-minute bouts of light-intensity walking (LW) or simple resistance activities (SRA) every 30 minutes improves postprandial cardiometabolic risk markers compared with uninterrupted sitting (SIT), according to a study published online April 13 in Diabetes Care.

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Medical Expulsive Therapy Underused for Ureteral Stones

THURSDAY, April 21, 2016 (HealthDay News) -- For patients with ureteral stones, medical expulsive therapy remains underused, according to a study published in the April issue of The Journal of Urology.

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Cow's Milk Allergy in Childhood May Lead to Lower Bone Density

THURSDAY, April 21, 2016 (HealthDay News) -- Children who are allergic to cow's milk may have lower bone mineral density than those with other food allergies, according to a study published online April 20 in Pediatrics.

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Do Antihistamines Blunt Exercise Recovery?

THURSDAY, April 21, 2016 (HealthDay News) -- Histamine may contribute to exercise recovery in skeletal muscle, and blockade of histamine receptors may interfere with that mechanism, according to research published online April 9 in the Journal of Physiology.

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Improved Survival for Certain Cancers With Low-Dose Aspirin

THURSDAY, April 21, 2016 (HealthDay News) -- Patients with colorectal, breast, or prostate cancers may have better survival odds if they are on a low-dose aspirin regimen, according to a review published online April 20 in PLOS ONE.

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No Solid Evidence for Pre-Participation Screens in Athletes

THURSDAY, April 21, 2016 (HealthDay News) -- There is no solid evidence for the effectiveness of pre-participation screening in reducing the number of sudden cardiac deaths among young athletes, according to an analysis published online April 20 in The BMJ.

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DiaRem Score Predicts Who Will Be Cured by RYGB Surgery

WEDNESDAY, April 20, 2016 (HealthDay News) -- For patients with type 2 diabetes, the DiaRem score can identify those who are likely to be cured by Roux-en-Y gastric bypass (RYGB) surgery, according to a research letter published online April 20 in JAMA Surgery.

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BRCA1 Mutation May Reduce Women's Fertility

WEDNESDAY, April 20, 2016 (HealthDay News) -- The BRCA1 gene mutation may also be tied to potential fertility issues, according to a report published online April 20 in Human Reproduction.

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CBT Helps Teens With Depression Who Refuse Antidepressants

WEDNESDAY, April 20, 2016 (HealthDay News) -- Teenagers with depression who refuse antidepressants may benefit from cognitive behavioral therapy, according to a study published online April 20 in Pediatrics.

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Ten Cases of Rare Bloodstream Infection Reported in Illinois

WEDNESDAY, April 20, 2016 (HealthDay News) -- A cluster of rare bloodstream infections was discovered by Illinois health officials while investigating an outbreak in Wisconsin.

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Digital Assistant in Closed-Loop Control Mode Beneficial in T1DM

WEDNESDAY, April 20, 2016 (HealthDay News) -- For patients with type 1 diabetes, a portable, wearable, wireless artificial pancreas system (the Diabetes Assistant [DiAs]) improves glucose control at home in closed-loop control (CLC) modes, according to a study published online April 13 in Diabetes Care.

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In Breast CA, Cardiotoxicity Up With Trastuzumab-Based Chemo

WEDNESDAY, April 20, 2016 (HealthDay News) -- For adult women with breast cancer, trastuzumab-based regimens are associated with increased risk of cardiotoxicity, according to a study published online April 18 in the Journal of Clinical Oncology.

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LDL Reduction in Hypertriglyceridemia Varies Per Statin

WEDNESDAY, April 20, 2016 (HealthDay News) -- For patients with hypertriglyceridemia, low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) reductions depend of the choice and dose of statin, according to research published in the May 1 issue of The American Journal of Cardiology.

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Decrease in Prostate CA Mortality Parallels Drop in Smoking

WEDNESDAY, April 20, 2016 (HealthDay News) -- Declines in prostate cancer mortality seem to parallel declines in cigarette smoking, based on data from four U.S. states. The report was published online April 14 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Diffusion-Weighted Imaging + MRI OK for Undescended Testes

WEDNESDAY, April 20, 2016 (HealthDay News) -- Combined diffusion-weighted imaging (DWI) and magnetic resonance imaging (MRI) show a greater performance compared to conventional MRI alone for identification of non-palpable undescended testes (UDTs), according to a study published online April 6 in the Journal of Medical Imaging and Radiation Oncology.

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Lower CVD Mortality for Metformin Versus Sulfonylureas

TUESDAY, April 19, 2016 (HealthDay News) -- Metformin is associated with reduced cardiovascular mortality compared with sulfonylureas, according to a large analysis published online April 19 in the Annals of Internal Medicine.

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Novel Case of Alzheimer's Reported in HIV+ Patient

TUESDAY, April 19, 2016 (HealthDay News) -- The first case of Alzheimer's disease (AD) diagnosed in a person with HIV suggests progressive dementia in older HIV+ individuals may be due to HIV-associated neurocognitive disorder (HAND), AD, or both. The case study was published online April 14 in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

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Review: Paroxetine Reduces Vasomotor Symptoms

TUESDAY, April 19, 2016 (HealthDay News) -- For perimenopausal and postmenopausal women, paroxetine reduces vasomotor symptoms, according to a review and meta-analysis published online April 7 in BJOG: An International Journal of Obstetrics and Gynaecology.

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Mineralocorticoid Receptor Antagonists No Benefit Post MI

TUESDAY, April 19, 2016 (HealthDay News) -- For patients with post-myocardial infarction (MI) heart failure, mineralocorticoid receptor antagonists (MRAs) do not improve outcome, according to a study published in the April 26 issue of the Journal of the American College of Cardiology.

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Network Meta-Analysis Recommends Prostaglandins for Glaucoma

TUESDAY, April 19, 2016 (HealthDay News) -- Network meta-analysis, which compares multiple treatment options, suggests that prostaglandins are best for decreasing intraocular pressure at three months in primary open angle-glaucoma (POAG), according to research published online April 19 in the Annals of Internal Medicine.

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Post-Op Gouty Arthritis Described in Patient Taking Thiazide

TUESDAY, April 19, 2016 (HealthDay News) -- A case of postoperative acute gouty arthritis following laparoscopic cholecystectomy with umbilical hernioplasty, secondary to hydrochlorothiazide use, has been documented in a case report published in the March issue in the Journal of Pharmacy Practice and Research.

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Suboptimal Guideline Adherence for Hematuria After Menopause

TUESDAY, April 19, 2016 (HealthDay News) -- The prevalence of urinary tract malignancy is low among postmenopausal women evaluated for asymptomatic microscopic hematuria, according to a study published in the April issue of The Journal of Urology.

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Article Offers Ways to Address Overlooked Details in Practice

MONDAY, April 18, 2016 (HealthDay News) -- Looking at a family medicine practice with fresh eyes can help address unsightly issues that patients notice, according to an article published in Family Practice Management.

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Physicians May Be Ordering Carotid Imaging Too Often

MONDAY, April 18, 2016 (HealthDay News) -- Many heart patients undergo carotid imaging for uncertain or inappropriate reasons, according to a study published online April 18 in JAMA Internal Medicine.

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ACOG Responds to CDC Update on Zika Causing Microcephaly

MONDAY, April 18, 2016 (HealthDay News) -- The U.S. Centers for Disease Control and Prevention has referred to Zika virus as causing microcephaly and other birth defects, according to a report published by the American College of Obstetrics and Gynecology (ACOG).

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Testosterone Undecanoate Cuts Anemia in Hypogonadal Men

MONDAY, April 18, 2016 (HealthDay News) -- Testosterone undecanoate reduces anemia in patients with subnormal testosterone levels, according to a study published in the April issue of The Journal of Urology.

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Vitamin D Supplementation Cuts Aeroallergen Sensitization

MONDAY, April 18, 2016 (HealthDay News) -- Vitamin D supplementation during pregnancy and infancy may reduce aeroallergen sensitization in children, according to a study published online April 6 in Allergy.

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Doctors, Midwives Struggle With Guilt After Traumatic Childbirth

MONDAY, April 18, 2016 (HealthDay News) -- Most Danish obstetricians and midwives report having been involved in a traumatic childbirth, and frequently have inner struggles with guilt and existential considerations, according to research published online April 13 in Acta Obstetricia et Gynecologica Scandinavica.

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Antithrombotic Rx Could Be Optimized for Older A-Fib Patients

MONDAY, April 18, 2016 (HealthDay News) -- A considerable proportion of older patients with atrial fibrillation (AF) are not prescribed antithrombotics, according to a study published online April 7 in the Journal of Clinical Pharmacy and Therapeutics.

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No Racial Difference in Prognostic Value of Cardiorespiratory Fitness

FRIDAY, April 15, 2016 (HealthDay News) -- Cardiorespiratory fitness (CRF) predicts all-cause mortality, with no racial differences in its prognostic value, according to a study published in the May 1 issue of The American Journal of Cardiology.

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Simulation Helps Residents Prepare for Global Rotations

FRIDAY, April 15, 2016 (HealthDay News) -- Simulation can help pediatric residents prepare for global health electives (GHE), according to an article published online April 13 in Pediatrics.

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2016 Match Marks Record Highs for Registrants, Matching

FRIDAY, April 15, 2016 (HealthDay News) -- The 2016 Match was the largest ever recorded by the National Resident Matching Program, with a higher match rate that 2015, according to a report from the American Medical Association.

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Metformin May Reduce Cancer Mortality Risk

FRIDAY, April 15, 2016 (HealthDay News) -- Metformin may reduce the risk of dying from some cancers for postmenopausal women with type 2 diabetes, according to a study published in the April 15 issue of the International Journal of Cancer.

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Proton Pump Inhibitors Tied to Chronic Kidney Disease

FRIDAY, April 15, 2016 (HealthDay News) -- Patients who regularly use proton pump inhibitors (PPIs) may be at increased risk of developing chronic kidney disease, according to research published online April 14 in the Journal of the American Society of Nephrology.

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Abdominal Aortic Aneurysm Odds Up for Patients With Psoriasis

FRIDAY, April 15, 2016 (HealthDay News) -- Psoriasis patients may face a higher risk of an abdominal aortic aneurysm, according to a study published online April 14 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Telephone Follow-Up Effective for Stage I Endometrial Cancer

FRIDAY, April 15, 2016 (HealthDay News) -- For women treated for stage I endometrial cancer, telephone follow-up (TFU) is noninferior to hospital-based follow-up (HFU), according to a study published online April 7 in BJOG: An International Journal of Obstetrics and Gynaecology.

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Improved Functional Outcomes With Adoption of GWTG-Stroke

FRIDAY, April 14, 2016 (HealthDay News) -- Adoption of the Get With The Guidelines (GWTG)-Stroke program is associated with improved functional outcomes at discharge and reduced post-discharge mortality for Medicare beneficiaries with acute stroke, according to a study published online April 14 in Stroke.

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Severe Cerebral Damage ID'd on Imaging in Children With Zika

FRIDAY, April 15, 2016 (HealthDay News) -- Children with congenital infection, presumably associated with the Zika virus, have severe cerebral damage identified on imaging, according to a study published online April 13 in The BMJ.

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Decrease in Medicare Spending for 2012 ACO Entrants

FRIDAY, April 15, 2016 (HealthDay News) -- Early reductions in Medicare spending were seen for the first full year of Medicare Shared Savings Program (MSSP) contracts for 2012 Accountable Care Organization (ACO) entrants, according to a study published online April 13 in the New England Journal of Medicine.

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Health Care Workers Skip Hand Washing One-Third of the Time

THURSDAY, April 14, 2016 (HealthDay News) -- Staff at many outpatient health care facilities in New Mexico failed to follow recommendations for hand hygiene more than one-third of the time, according to findings published in the April 1 issue of the American Journal of Infection Control.

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CDC: Zika Link to Microcephaly, Brain Damage Confirmed

THURSDAY, April 14, 2016 (HealthDay News) -- Zika virus is a definite and direct cause of microcephaly and other brain-related birth defects, health officials from the U.S. Centers for Disease Control and Prevention announced Wednesday. The CDC made its announcement following an evidence review published online April 13 in the New England Journal of Medicine.

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Pediatric Pneumonia Can Be Diagnosed Via Lung Ultrasound

THURSDAY, April 14, 2016 (HealthDay News) -- Lung ultrasounds may offer a safer, yet equally effective, alternative to chest X-rays for diagnosing pneumonia in children, according to a study published recently in Chest.

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Surveillance Seems Safe for Some Intermediate Risk Prostate CA

THURSDAY, April 14, 2016 (HealthDay News) -- For men with prostate cancer, active surveillance seems safe for those at low risk and for select patients at intermediate risk, according to a study published in The Journal of Urology.

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Brain Network Charts Could Help Predict Attention Impairment

THURSDAY, April 14, 2016 (HealthDay News) -- Growth charting methods identify a correlation between intrinsic connectivity networks (ICN) and attention performance, according to a study published online April 13 in JAMA Psychiatry.

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Progress Made in Comprehensive Primary Care Initiative

THURSDAY, April 14, 2016 (HealthDay News) -- Two years into the Comprehensive Primary Care Initiative, practices have made progress toward transforming delivery of primary care but have not yet shown savings in expenditures, according to a study published online April 13 in the New England Journal of Medicine.

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Self-Management Group Rehab Benefits Persons With Dementia

THURSDAY, April 14, 2016 (HealthDay News) -- Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in the Journal of the American Geriatrics Society.

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Consumption of Fast Food Linked to Greater Exposure to Phthalates

WEDNESDAY, April 13, 2016 (HealthDay News) -- People with high intake of fast food may have levels of phthalates in their urine that are 24 to 40 percent higher than people who rarely eat fast food, according to research published online April 13 in Environmental Health Perspectives.

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Benefits of Polyunsaturated Over Saturated Fat Deemed Uncertain

WEDNESDAY, April 13, 2016 (HealthDay News) -- Controversial new research challenges the idea that heart health will improve if people cut saturated fat -- typically from animal sources -- from their diets in favor of vegetable oil. The findings were published online April 12 in The BMJ.

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Coalition Calls for Changes to Hospital Pain Assessments

WEDNESDAY, April 13, 2016 (HealthDay News) -- U.S. hospital procedures and questionnaires used to manage patient pain lead to overprescribing of addictive opioids and need to be changed, critics say.

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Clinical Scores Correlate Well in Pediatric Atopic Dermatitis

WEDNESDAY, April 13, 2016 (HealthDay News) -- For children with atopic dermatitis, clinical scores for sleep loss, pruritus, disease severity, and quality of life correlate well, according to a study published online April 8 in the British Journal of Dermatology.

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Potentially Inappropriate Meds Use Common With OAB Tx

WEDNESDAY, April 13, 2016 (HealthDay News) -- For older adults starting antimuscarinic treatment for overactive bladder (OAB), potentially inappropriate medication (PIM) use is highly prevalent and associated with greater total costs, according to a study published online April 5 in the Journal of the American Geriatrics Society.

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Review: Low Risk of Birth Defects With Ondansetron Exposure

WEDNESDAY, April 13, 2016 (HealthDay News) -- The offspring of women using ondansetron early in pregnancy for nausea and vomiting of pregnancy or hyperemesis gravidarum may be at risk for cardiac abnormalities, although the overall risk of birth defects associated with exposure appears low, according to a review published in the May issue of Obstetrics & Gynecology.

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Clinical Decision Support Tool Cuts CT Use for Appendicitis

WEDNESDAY, April 13, 2016 (HealthDay News) -- The implementation of a multicomponent electronic clinical decision support tool reduces computed tomography (CT) use for pediatric patients with possible appendicitis, according to a study published online April 13 in Pediatrics.

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Computerized Order Set Aids Prescribing in COPD Exacerbations

WEDNESDAY, April 13, 2016 (HealthDay News) -- Implementation of a computerized multidisciplinary order set in the electronic health record improves the quality of physician pharmacologic prescribing for patients hospitalized for chronic obstructive pulmonary disorder (COPD) exacerbations, according to research published online April 8 in the Annals of the American Thoracic Society.

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Low Fruit, Vegetable Intake Linked to Hip Fracture Risk

WEDNESDAY, April 13, 2016 (HealthDay News) -- For older adults, daily intake of no more than one serving of fruit and vegetables is associated with increased risk of hip fracture relative to moderate intake, according to a study published online April 8 in the Journal of Bone and Mineral Research.

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CV Risk Not Significantly Different for GLP-1 Receptor Agonists

TUESDAY, April 12, 2016 (HealthDay News) -- There are no significant differences in occurrence of cardiovascular disease (CVD) tied to treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RA) compared with dipeptidyl peptidase-4 inhibitors (DPP-4i), second generation sulfonylureas, or insulin, in combination with metformin, according to a study published online March 22 in Diabetes, Obesity and Metabolism.

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Parental Hip Fracture Independently Ups Offspring Risk

TUESDAY, April 12, 2016 (HealthDay News) -- Parental hip fracture (HF) is independently associated with increased risk of offspring major osteoporotic fracture (MOF) and HF, according to research published online April 8 in the Journal of Bone and Mineral Research.

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Androgen Deprivation Tx for Prostate CA Tied to Depression

TUESDAY, April 12, 2016 (HealthDay News) -- Older men who receive androgen deprivation therapy (ADT) for prostate cancer may be at increased risk of developing depression, according to a new, large study published online April 11 in the Journal of Clinical Oncology.

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Doctors Can Be Misled About FDA 'Breakthrough' Drug Designation

TUESDAY, April 12, 2016 (HealthDay News) -- Use of the word "breakthrough" in the U.S. Food and Drug Administration's expedited approval process could mislead doctors about the new drugs' actual benefits, according to a research letter published in the April 12 issue of the Journal of the American Medical Association.

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Early Warning Trigger Tool Could Help Reduce Maternal Morbidity

TUESDAY, April 12, 2016 (HealthDay News) -- Use of a clinical pathway-specific Maternal Early Warning Trigger (MEWT) tool can reduce maternal morbidity, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.

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Hospice Care Doesn't Up Costs for Nursing Home Decedents

TUESDAY, April 12, 2016 (HealthDay News) -- For long-stay nursing home (NH) decedents, use of hospice does not increase Medicare costs in the six months before death, according to a study published online April 5 in the Journal of the American Geriatrics Society.

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ASCO Presents Guidelines for Increasing HPV Vaccine Uptake

TUESDAY, April 12, 2016 (HealthDay News) -- Recommendations have been developed to increase human papillomavirus (HPV) vaccine uptake, according to an American Society for Clinical Oncology (ASCO) special article published online April 11 in the Journal of Clinical Oncology.

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Review Addresses Chest Pain in Young Adults Presenting to ER

TUESDAY, April 12, 2016 (HealthDay News) -- For young adults presenting to the emergency department with acute chest pain, after ruling out cardiac risk, physicians should focus on stress reaction, according to a review published in the March issue of the Journal of Emergency Nursing.

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Efficacy of DTaP, Tdap Holds Despite Pertactin Deficiency

TUESDAY, April 12, 2016 (HealthDay News) -- Despite an increased proportion of Bordetella pertussis isolates lacking pertactin, vaccine effectiveness (VE) is still high in Vermont for the five-dose diphtheria, tetanus, and acellular pertussis vaccine (DTaP) series and the tetanus, diphtheria, and acellular pertussis vaccine (Tdap), according to research published online April 12 in Pediatrics.

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Increase in Number of Patients Being Treated for Alpha-Gal

TUESDAY, April 12, 2016 (HealthDay News) -- There has been an increase in the number of patients being treated for Galactose-alpha-1,3-galactose (alpha-gal) syndrome, according to a report from the Vanderbilt University Medical Center's Asthma, Sinus and Allergy Program (ASAP).

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New-Onset A-Fib Post Acute MI Ups Complications, Readmission

TUESDAY, April 12, 2016 (HealthDay News) -- New-onset atrial fibrillation (AF) after acute myocardial infarction (AMI) is strongly tied to in-hospital complications and higher short-term readmission rates, according to a study published in the April 15 issue of The American Journal of Cardiology.

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USPSTF: Aspirin Recommended for Some Aged 50 to 69 Years

MONDAY, April 11, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends aspirin use for primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC) in certain adults aged 50 to 69 years, but not in younger or older adults. These findings form the basis of a recommendation statement, published online April 11 in the Annals of Internal Medicine.

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Hydrolyzed Egg Preparation Safe for Egg-Allergic Children

MONDAY, April 11, 2016 (HealthDay News) -- A low allergenic hydrolyzed egg (HydE) preparation seems to be safe for use in egg-allergic children, according to a study published online April 5 in Allergy.

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VA Commission on Care: Eliminate VA Medical Centers

MONDAY, April 11, 2016 (HealthDay News) -- A radical proposal has been suggested for eliminating all Veterans Affairs (VA) medical centers and outpatient facilities in the next 20 years, floated by seven of 15 members of the VA Commission on Care, according to an article published in the Military Times.

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Exenatide Twice Daily Deemed Efficacious Across BMI Ranges

MONDAY, April 11, 2016 (HealthDay News) -- For patients with type 2 diabetes, exenatide twice daily added to insulin glargine is efficacious across body mass index (BMI) ranges, according to a study published online March 29 in Diabetes, Obesity and Metabolism.

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Progesterone Attenuates Drug-Induced QT Interval Lengthening

MONDAY, April 11, 2016 (HealthDay News) -- For healthy females, oral progesterone administration attenuates drug-induced QT interval lengthening, according to a study published online April 6 in JACC: Clinical Electrophysiology.

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Definition of Prolonged Third-Stage Labor May Be Outdated

MONDAY, April 11, 2016 (HealthDay News) -- Postpartum hemorrhage risk is significantly elevated with a third-stage labor duration of 20 minutes or more, according to research published in the May issue of Obstetrics & Gynecology.

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Colonic Diverticular Disease Linked to Dementia Risk

MONDAY, April 11, 2016 (HealthDay News) -- Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in the Journal of Gastroenterology and Hepatology.

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Niacin-ER May Be Overlooked Cause of Thrombocytopenia

FRIDAY, April 8, 2016 (HealthDay News) -- Extended-release (ER) niacin is associated with progressive and reversible thrombocytopenia, according to a letter to the editor published online March 25 in the American Journal of Hematology.

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Propranolol Use Tied to Increased Mortality in Child-Pugh B, C

FRIDAY, April 8, 2016 (HealthDay News) -- For patients with Child-Pugh B and C, propranolol use is associated with increased mortality, according to a letter to the editor published online March 26 in Hepatology.

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World Trade Center Exposure, Eosinophilia Predict Sinus Surgery

FRIDAY, April 8, 2016 (HealthDay News) -- Sinus surgery is more common among firefighters who responded during the first two days of the World Trade Center disaster than those who had less intense or shorter exposures, according to a study published online April 8 in the Annals of the American Thoracic Society. The same was found to be true for those firefighters who were at the site for six months or more.

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Diabetes Weight Loss Diets Improve Emotional Measures

FRIDAY, April 8, 2016 (HealthDay News) -- Among patients with type 2 diabetes mellitus (T2DM), weight loss diets, regardless of composition, improve psychological measures, including depression, mood, and quality of life, according to a study published online March 23 in the Journal of Internal Medicine.

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Hormone Tx No Harm After Nonserous Epithelial Ovarian CA

FRIDAY, April 8, 2016 (HealthDay News) -- For women with nonserous epithelial ovarian cancer, hormone therapy (HT) after treatment does not reduce survival, according to a study published in the May issue of Obstetrics & Gynecology.

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Liraglutide Is Not Justified for All Patients With T1DM

FRIDAY, April 8, 2016 (HealthDay News) -- For patients with type 1 diabetes mellitus (T1DM), addition of 1.2 and 1.8 mg of liraglutide to insulin over a 12-week period is associated with a modest reduction in weekly mean glucose levels, according to a study published online April 5 in Diabetes Care.

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ACEI/ARBs Up AMI Outcomes Regardless of Renal Status

FRIDAY, April 8, 2016 (HealthDay News) -- For acute myocardial infarction (AMI) survivors, angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) treatment is associated with improved long-term survival, according to research published in the April 12 issue of the Journal of the American College of Cardiology.

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Cushing's Sx Described in Infant Treated With Ophthalmic Steroid

FRIDAY, April 8, 2016 (HealthDay News) -- In a case report published online April 7 in Pediatrics, iatrogenic Cushing's syndrome (ICS) is described in an infant following intranasal usage of dexamethasone ophthalmic solution.

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Medical Costs Up for Late Middle-Aged With Hearing Loss

THURSDAY, April 7, 2016 (HealthDay News) -- Hearing loss is associated with higher medical costs for late middle-aged adults, according to a research letter published online April 7 in JAMA Otolaryngology-Head & Neck Surgery.

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Sport-Banned Oxilofrine Found in Diet Supplements

THURSDAY, April 7, 2016 (HealthDay News) -- A stimulant banned from competitive sports, oxilofrine, has been found in more than a dozen dietary supplements marketed for "burning" body fat, according to a study published online April 7 in Drug Testing and Analysis.

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Daily Fresh Fruit Intake May Improve Cardiovascular Health

THURSDAY, April 7, 2016 (HealthDay News) -- Eating fresh fruit regularly may help prevent heart attacks and strokes, according to a study published in the April 7 issue of the New England Journal of Medicine.

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New Dietary Guidelines for Americans Issued for 2015-2020

THURSDAY, April 7, 2016 (HealthDay News) -- New U.S. dietary guidelines have been released for 2015 to 2020, according to a health policy brief published online March 31 in Health Affairs.

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Sacubitril-Valsartan May Be Cost-Effective Option in HFrEF

THURSDAY, April 7, 2016 (HealthDay News) -- For patients with heart failure with reduced ejection fraction (HFrEF), sacubitril-valsartan may be cost-effective, depending on the willingness-to-pay threshold, according to a study published online March 30 in JACC: Heart Failure.

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Since 1980, Diabetes Cases Have Quadrupled Globally

WEDNESDAY, April 6, 2016 (HealthDay News) -- The number of adults worldwide with diabetes has quadrupled in the past 35 years, according to a report published online April 6 in The Lancet.

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FDA Approves Inflectra as 'Biosimilar' to Remicade

WEDNESDAY, April 6, 2016 (HealthDay News) -- The U.S. Food and Drug Administration has approved its second-ever "biosimilar" drug, Inflectra, for adults with Crohn's disease, rheumatoid arthritis, or chronic plaque psoriasis, among other prescribed uses.

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Subclinical Cardiac Dysfunction Frequent in Hispanics/Latinos

WEDNESDAY, April 6, 2016 (HealthDay News) -- Hispanics/Latinos frequently have cardiac dysfunction, which is usually subclinical or unrecognized, according to a study published online April 5 in Circulation: Heart Failure.

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FDA Issues New Warning for Two Diabetes Medications

WEDNESDAY, April 6, 2016 (HealthDay News) -- Diabetes medications containing saxagliptin and alogliptin may raise the risk of heart failure, particularly in patients with heart or kidney disease, U.S. health officials warned Tuesday.

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Cost of Insulin Found to Have Tripled Over Past Decade

WEDNESDAY, April 6, 2016 (HealthDay News) -- The price of insulin has tripled in only 10 years, according to a letter published in the April 5 issue of the Journal of the American Medical Association. Moreover, since 2010, per-person spending on insulin in the United States was more than spending on all other diabetes drugs.

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Diuretic Dose Not Linked to Outcome in Heart Failure

WEDNESDAY, April 6, 2016 (HealthDay News) -- For patients with worsening heart failure, after adjustment for pre-specified covariates of disease severity, diuretic dose is not associated with mortality and heart failure rehospitalization, according to a study published online March 30 in JACC: Heart Failure.

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Distress Still High After Chemo Completion in Childhood ALL

WEDNESDAY, April 6, 2016 (HealthDay News) -- Emotional distress is common in children during and after therapy for childhood acute lymphoblastic leukemia (ALL), according to a study published online March 29 in Cancer.

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USPSTF Recommends Against COPD Screening in Adults

TUESDAY, April 5, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends against screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults. These findings form the basis of a recommendation statement published online April 5 in the Journal of the American Medical Association.

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More Risky Drinking Behaviors for Women With Eating Disorders

TUESDAY, April 5, 2016 (HealthDay News) -- Women with eating disorders more often exhibit risky drinking behaviors than their unaffected peers, according to a study published online April 1 in the International Journal of Eating Disorders.

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Quality of Urgent Health Care Varies for Virtual Visits

TUESDAY, April 5, 2016 (HealthDay News) -- For companies providing virtual visits for management of common acute illness there is significant variation in quality of care, according to a study published online April 4 in JAMA Internal Medicine.

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Hypoglycemia, Sleep Loss Prolong Cognitive Impairment

TUESDAY, April 5, 2016 (HealthDay News) -- Sleep deprivation does not exacerbate cognitive impairment induced by hypoglycemia, but the post-hypoglycemia recovery takes longer with persistence of both cognitive dysfunction and hypoglycemia symptoms, according to a study published online March 22 in Diabetes Care.

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CDC Hosts Zika Action Plan Summit

MONDAY, April 4, 2016 (HealthDay News) -- More than 300 public health experts attended the Zika Action Plan Summit, hosted by the U.S. Centers for Disease Control and Prevention, in Atlanta on Friday. The summit was held to help ensure a coordinated response to the mosquito-borne illness.

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Sensory Interventions Can Benefit Patients With Dementia

MONDAY, April 4, 2016 (HealthDay News) -- For patients with dementia, there are many available sensory interventions that seem to have significant effects, according to a review published online March 31 in the Journal of Clinical Nursing.

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New Utah State Law Requires Anesthesia During Abortion

MONDAY, April 4, 2016 (HealthDay News) -- Utah is the first state to require anesthesia for women having an abortion at 20 weeks of pregnancy or later.

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Are Guidelines Needed to Assess Competence of Aging Physicians?

FRIDAY, April 1, 2016 (HealthDay News) -- The question of whether national guidelines need to be developed for assessing the competence of aging physicians was discussed during a recent meeting of key stakeholders, according to a news release from the American Medical Association (AMA).

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Child Mental Health Care Varies Widely in Primary Care Settings

FRIDAY, April 1, 2016 (HealthDay News) -- For children aged 4 to 18 years, mental health diagnoses and psychotropic medication prescribing vary across practices in the United States, according to a review published online April 1 in Pediatrics.

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Even Light-Use Waterpipe Smoking Harms the Lungs

FRIDAY, April 1, 2016 (HealthDay News) -- Young, light-use waterpipe smokers exhibit a variety of pulmonary abnormalities, according to a study published online March 23 in the American Journal of Respiratory and Critical Care Medicine.

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Chances of Meeting 2025 Global Obesity Target Near Zero

FRIDAY, April 1, 2016 (HealthDay News) -- Since 1975, the mean body mass index (BMI) of men and women has increased and trends in obesity have been increasing worldwide, according to a study published in the April 2 issue of The Lancet.

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