April 2016 Briefing - Dermatology

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Here are what the editors at HealthDay consider to be the most important developments in Dermatology for April 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Guidelines Developed for Management of Atopic Dermatitis

FRIDAY, April 29, 2016 (HealthDay News) -- Guidelines have been developed for the management of atopic dermatitis (AD). The guidelines were published online April 14 in The Journal of Dermatology.

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Wide Variation in Health Care Costs Across the U.S.

FRIDAY, April 29, 2016 (HealthDay News) -- Health care prices vary widely across the United States, even within the same state, according to a study published in the April issue of Health Affairs.

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Rosacea Linked to Increased Risk of Dementia

THURSDAY, April 28, 2016 (HealthDay News) -- Rosacea may be linked to a higher risk for dementia, particularly Alzheimer's disease (AD), according to research published online April 28 in the Annals of Neurology.

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Article Discusses Workplace Violence in Health Care

THURSDAY, April 28, 2016 (HealthDay News) -- There is a lack of data relating to the prevalence of workplace violence in health care and how to address it, according to a review article published in the April 28 issue of the New England Journal of Medicine.

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Research Finds Link Between Psoriasis, Obesity, T2DM

THURSDAY, April 28, 2016 (HealthDay News) -- Psoriasis may be linked to excess weight and type 2 diabetes, according to a study published online April 27 in JAMA Dermatology.

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Multiple Techniques Available for Sunken Superior Sulcus

THURSDAY, April 28, 2016 (HealthDay News) -- Depending on clinical features, multiple techniques exist for correcting sunken superior sulcus, according to a review published online April 20 in the Journal of Cosmetic Dermatology.

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Preventive Topical Steroids Cut Atopic Dermatitis Severity

THURSDAY, April 28, 2016 (HealthDay News) -- Intermittent preventive administration of topical corticosteroids in children controls the severity of atopic dermatitis (AD), according to a study published online April 14 in the Journal of Dermatology.

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U.S. Health Report Card Finds Racial, Ethnic Disparities Persist

WEDNESDAY, April 27, 2016 (HealthDay News) -- An update on Americans' health finds that racial and ethnic disparities persist, with significant gaps in obesity, cesarean births, and dental care. But advances have been made in some important areas, including infant mortality rates, women smokers, and numbers of uninsured, according to the new report from the U.S. Department of Health and Human Services.

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Doctors Have a Only a Few Weeks Left to Review Financial Data

WEDNESDAY, April 27, 2016 (HealthDay News) -- Under the Physician Payments Sunshine Act, physicians have only a few weeks left to review and report disputes relating to their financial ties to drug and medical device manufacturers, according to the American Medical Association.

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Simvastatin/Ezetimibe Not Beneficial in Alopecia Areata

WEDNESDAY, April 27, 2016 (HealthDay News) -- Simvastatin/ezetimibe does not appear to be beneficial for severe alopecia areata (AA) in a sample of 20 patients, according to a letter to the editor published in the May issue of the Journal of the American Academy of Dermatology.

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SLICC/ACR Criteria Don't ID Severe Internal Disease in SCLE

WEDNESDAY, April 27, 2016 (HealthDay News) -- Neither the American College of Rheumatology (ACR) nor the Systemic Lupus International Collaborating Clinics (SLICC) criteria distinguishes patients with subacute cutaneous lupus erythematosus (SCLE) with major internal disease from those without, according to research published in the May issue of the Journal of the American Academy of Dermatology.

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A Doctor's View: EHRs Impair Physician-Patient Relationship

MONDAY, April 25, 2016 (HealthDay News) -- Electronic health records (EHRs) may be impairing the physician-patient relationship, according to an article published in Medical Economics.

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Rapid-Onset Diabetes Described With Anti-PD-1 Treatment

MONDAY, April 25, 2016 (HealthDay News) -- In a case report published online April 11 in the Journal of Diabetes Investigation, researchers document rapid-onset insulin-dependent diabetes in an Asian patient undergoing treatment with anti-programmed cell death-1 (anti-PD-1) therapy.

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Positive Midface Rejuvenation With Mesh Suspension Thread

MONDAY, April 25, 2016 (HealthDay News) -- Midface rejuvenation using novel modified mesh suspension thread produces positive aesthetic results and minimal complications, according to a small study published online April 18 in the Journal of Cosmetic Dermatology.

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Poor Persistence/Adherence With Long-Term Topical AK Treatment

MONDAY, April 25, 2016 (HealthDay News) -- A considerable proportion of patients with actinic keratosis (AK) receiving long-term topical treatment have poor persistence or adherence, according to a study published online April 18 in the British Journal of Dermatology.

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Physicians Can Get Involved in Developing Payment Models

FRIDAY, April 22, 2016 (HealthDay News) -- Doctors can be involved in developing new payment models for their practices, according to the American Medical Association.

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Ustekinumab More Effective Than TNF-α Inhibitors in Psoriasis

FRIDAY, April 22, 2016 (HealthDay News) -- For patients with psoriasis, ustekinumab is more effective than tumor necrosis factor-α inhibitors, according to a study published in the May issue of the Journal of the American Academy of Dermatology.

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Laser Plus Topical Antifungal Effective for Onychomycosis

THURSDAY, April 21, 2016 (HealthDay News) -- Fractional carbon dioxide laser therapy combined with topical antifungal is effective in the treatment of onychomycosis, according to a study published in the May issue of the Journal of the American Academy of Dermatology.

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Pembrolizumab Active in Patients With Advanced Melanoma

THURSDAY, April 21, 2016 (HealthDay News) -- Pembrolizumab is associated with an overall objective response rate of 33 percent in patients with advanced melanoma, and a higher rate for treatment-naive patients, according to a study published in the April 19 issue of the Journal of the American Medical Association.

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Trichloroacetic Acid Beats Cryotherapy for Plantar Warts

WEDNESDAY, April 20, 2016 (HealthDay News) -- Trichloroacetic acid (TCA) is more effective than cryotherapy with liquid nitrogen for the treatment of plantar warts, according to a study published online April 4 in the Journal of Dermatology.

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Oral Nicotinamide Safe for Renal Transplant Recipients

MONDAY, April 18, 2016 (HealthDay News) -- For renal transplant recipients, oral nicotinamide seems safe and is associated with nonsignificant reductions in new non-melanoma skin cancers (NMSCs), according to a study published online April 8 in the British Journal of Dermatology.

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Article Offers Ways to Address Overlooked Details in Practice

MONDAY, April 18, 2016 (HealthDay News) -- Looking at a family medicine practice with fresh eyes can help address unsightly issues that patients notice, according to an article published in Family Practice Management.

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2016 Match Marks Record Highs for Registrants, Matching

FRIDAY, April 15, 2016 (HealthDay News) -- The 2016 Match was the largest ever recorded by the National Resident Matching Program, with a higher match rate that 2015, according to a report from the American Medical Association.

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Decrease in Medicare Spending for 2012 ACO Entrants

FRIDAY, April 15, 2016 (HealthDay News) -- Early reductions in Medicare spending were seen for the first full year of Medicare Shared Savings Program (MSSP) contracts for 2012 Accountable Care Organization (ACO) entrants, according to a study published online April 13 in the New England Journal of Medicine.

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Abdominal Aortic Aneurysm Odds Up for Patients With Psoriasis

FRIDAY, April 15, 2016 (HealthDay News) -- Psoriasis patients may face a higher risk of an abdominal aortic aneurysm, according to a study published online April 14 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Health Care Workers Skip Hand Washing One-Third of the Time

THURSDAY, April 14, 2016 (HealthDay News) -- Staff at many outpatient health care facilities in New Mexico failed to follow recommendations for hand hygiene more than one-third of the time, according to findings published in the April 1 issue of the American Journal of Infection Control.

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For Rosacea, Ivermectin Offers Lasting Improvement in HRQoL

THURSDAY, April 14, 2016 (HealthDay News) -- For patients with rosacea, ivermectin treatment is associated with long-term improvement in health-related quality of life (HRQoL), according to a study published online April 8 in the British Journal of Dermatology.

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Clinical Scores Correlate Well in Pediatric Atopic Dermatitis

WEDNESDAY, April 13, 2016 (HealthDay News) -- For children with atopic dermatitis, clinical scores for sleep loss, pruritus, disease severity, and quality of life correlate well, according to a study published online April 8 in the British Journal of Dermatology.

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Doctors Can Be Misled About FDA 'Breakthrough' Drug Designation

TUESDAY, April 12, 2016 (HealthDay News) -- Use of the word "breakthrough" in the U.S. Food and Drug Administration's expedited approval process could mislead doctors about the new drugs' actual benefits, according to a research letter published in the April 12 issue of the Journal of the American Medical Association.

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Excision Margins Don't Impact Melanoma Recurrence, Survival

MONDAY, April 11, 2016 (HealthDay News) -- Wider excision margins in thick cutaneous melanoma cases do not improve locoregional recurrence or melanoma-specific survival (MSS), according to research published online March 25 in Head & Neck.

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VA Commission on Care: Eliminate VA Medical Centers

MONDAY, April 11, 2016 (HealthDay News) -- A radical proposal has been suggested for eliminating all Veterans Affairs (VA) medical centers and outpatient facilities in the next 20 years, floated by seven of 15 members of the VA Commission on Care, according to an article published in the Military Times.

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Cocoa Pod Extract Deemed Effective As Antiwrinkle Gel

FRIDAY, April 8, 2016 (HealthDay News) -- Cocoa pod extract (CPE) can be used as an active ingredient of antiwrinkle products, with effects seen after three weeks of application of CPE gel, according to a study published online April 4 in the Journal of Cosmetic Dermatology.

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Foreign Body Reaction Induced by Bee Sting Therapy

FRIDAY, April 8, 2016 (HealthDay News) -- Foreign body reaction can be induced by bee sting therapy, according to a letter to the editor published online March 31 in the Journal of Cutaneous Pathology.

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Considerable Agreement on Presence of BCC on Mohs Slides

THURSDAY, April 7, 2016 (HealthDay News) -- There is considerable interpersonal and intrapersonal agreement on the presence of basal cell carcinoma (BCC) on Mohs slides, according to a study published online April 1 in the British Journal of Dermatology.

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Incidence of Psoriatic Arthritis 2.7/100 Psoriasis Patients

THURSDAY, April 7, 2016 (HealthDay News) -- The incidence of psoriatic arthritis (PsA) is 2.7 cases per 100 psoriasis patients, with risk factors including severe psoriasis phenotype and low level of education, according to a study published in the April issue of Arthritis & Rheumatology.

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MC1R Variants May Up Melanoma Risk, Even Without Sun Exposure

WEDNESDAY, April 6, 2016 (HealthDay News) -- Genetics could play a role in the development of melanoma even for skin without extensive sun exposure, according to a study published online April 6 in JAMA Dermatology.

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FDA Approves Inflectra as 'Biosimilar' to Remicade

WEDNESDAY, April 6, 2016 (HealthDay News) -- The U.S. Food and Drug Administration has approved its second-ever "biosimilar" drug, Inflectra, for adults with Crohn's disease, rheumatoid arthritis, or chronic plaque psoriasis, among other prescribed uses.

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Bioengineering Advances Offer Promise for Skin Regeneration

FRIDAY, April 1, 2016 (HealthDay News) -- An in vivo transplantation model has been used to develop a three-dimensional (3D) integumentary organ system from induced pluripotent stem cells, according to research published online April 1 in Science Advances.

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Treatment Guidelines Lacking for Molluscum Contagiosum in HIV+

FRIDAY, April 1, 2016 (HealthDay News) -- High-quality studies are lacking in assessing interventions for molluscum contagiosum (MC) in HIV-positive patients, according to a review published online March 18 in the International Journal of Dermatology.

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Are Guidelines Needed to Assess Competence of Aging Physicians?

FRIDAY, April 1, 2016 (HealthDay News) -- The question of whether national guidelines need to be developed for assessing the competence of aging physicians was discussed during a recent meeting of key stakeholders, according to a news release from the American Medical Association (AMA).

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