April 2015 Briefing - Gastroenterology

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Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for April 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Metabolic 'Map' May One Day Help Predict Obesity Risk

THURSDAY, April 30, 2015 (HealthDay News) -- Researchers say they have successfully linked certain byproducts of digestion to the risk of excess body fat. The findings were published in the April 29 issue of Science Translational Medicine.

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Lack of Adequate Sunlight May Up Risk of Pancreatic Cancer

THURSDAY, April 30, 2015 (HealthDay News) -- People who live in regions with low sunlight may have a higher risk of pancreatic cancer, possibly because they don't get enough vitamin D from the sun, new research suggests. The study appears online April 30 in the Journal of Steroid Biochemistry and Molecular Biology.

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Sodium Nitrate, Citric Acid Effective for Anogenital Warts

THURSDAY, April 30, 2015 (HealthDay News) -- For patients with anogenital warts, high-dose topical treatment (sodium nitrite, 6 percent, with citric acid, 9 percent) is more effective than placebo, according to a study published online April 29 in JAMA Dermatology.

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Colon Cancer Risk Markers Appear Within Two Weeks of Diet Change

WEDNESDAY, April 29, 2015 (HealthDay News) -- Westernization of the diet induces changes in biomarkers of colon cancer risk within two weeks, according to research published online April 28 in Nature Communications.

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Physician Compensation Up for Most Specialties

TUESDAY, April 28, 2015 (HealthDay News) -- Physician compensation has gone up for almost all specialties, according to a 2015 report published by Medscape.

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Capsule Colonoscopy Deemed 'Adequate' Alternative

TUESDAY, April 28, 2015 (HealthDay News) -- In an average-risk screening population, capsule colonoscopy seems adequate for patients who cannot undergo colonoscopy or who had incomplete colonoscopies, although additional research is needed to improve capsule detection, according to a study published in the May issue of Gastroenterology.

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CDC: Surveillance System Can Help Reduce Health Care Injuries

TUESDAY, April 28, 2015 (HealthDay News) -- A surveillance system for health care facilities can be used to identify and help reduce the number of preventable injuries among health care personnel, according to research published in the April 24 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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CRC Screening Among Older Adults Often Inappropriate

FRIDAY, April 24, 2015 (HealthDay News) -- Older adults with limited life expectancy (LE) frequently receive colorectal cancer (CRC) screening, according to a study published in the April issue of the Journal of the American Geriatrics Society.

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Prednisolone, Pentoxifylline Little Use in Alcoholic Hepatitis

THURSDAY, April 23, 2015 (HealthDay News) -- Prednisolone and pentoxifylline are associated with limited and no benefits, respectively, for severe alcoholic hepatitis, according to a study published in the April 23 issue of the The New England Journal of Medicine.

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Concomitant Metformin, GERD Meds Up Vitamin B12 Depletion

THURSDAY, April 23, 2015 (HealthDay News) -- Concomitant use of metformin and histamine H2-receptor antagonists or proton pump inhibitors has the potential to induce vitamin B12 depletion and neuropathy, according to research published in the April issue of Clinical Diabetes.

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Second Primaries for Over 25% With Metastatic Prostate Cancer

THURSDAY, April 23, 2015 (HealthDay News) -- More than one-quarter of patients with metastatic prostate cancer present with a synchronous second primary malignancy, according to a review published in the April issue of The Journal of Urology.

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EHR Data Mining Helps With Quality Improvement

WEDNESDAY, April 22, 2015 (HealthDay News) -- Electronic health records (EHRs) are a valuable source of data that can be mined to help practices with quality improvement performance, according to a study published in Medical Economics.

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EHR Decision Support Ups Radiologic Test Appropriateness

TUESDAY, April 21, 2015 (HealthDay News) -- Computerized clinical decision-support (CCDS) capabilities of electronic health records may improve appropriate use of diagnostic radiologic test ordering and reduce test use, according to a review published in the April 21 issue of the Annals of Internal Medicine.

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'Westernization' May Drive Disease Via Microbiome

TUESDAY, April 21, 2015 (HealthDay News) -- In a discovery that could eventually shed light on some diseases that plague modern society, a tribe in a remote part of the Amazon jungle in Venezuela appears to have microbiomes with the highest diversity of bacteria and genetic functions ever found.

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Guidance Offered for Managing Conflict With Patients

MONDAY, April 20, 2015 (HealthDay News) -- Good communication is key to managing conflict with patients, according to an article published April 1 in Medical Economics.

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Suboptimal Prescribing Attitudes Could Signal Personal Distress

FRIDAY, April 17, 2015 (HealthDay News) -- Medical students in personal distress may be more likely to have suboptimal attitudes about self-prescribing and personal responsibility for reporting impaired colleagues, according to a study published in the April issue of Academic Medicine.

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Medicare Spending Down in Year One of Pioneer ACO

THURSDAY, April 16, 2015 (HealthDay News) -- Medicare spending is down in year one of the Pioneer accountable care organization (ACO) program, according to a study published online April 15 in the New England Journal of Medicine.

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Ethical Implications for Looking Up Applicants on Facebook

THURSDAY, April 16, 2015 (HealthDay News) -- Looking up students on Facebook and other social networking sites (SNS) is associated with ethical concerns, according to a perspective piece published in the March issue of the Journal of Graduate Medical Education.

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AMA Announces End of Sustainable Growth Rate Formula

WEDNESDAY, April 15, 2015 (HealthDay News) -- Recently adopted legislation has repealed the sustainable growth rate (SGR) formula, according to a report published by the American Medical Association (AMA).

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Concomitant, Sequential Tx Similar for H. pylori Eradication

WEDNESDAY, April 15, 2015 (HealthDay News) -- For eradication of Helicobacter pylori infection, concomitant therapy (CT) is equivalent to sequential therapy (ST), and hybrid therapy offers similar efficacy to CT, according to research published online April 13 in the Journal of Gastroenterology and Hepatology.

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Statin Use Inversely Linked to Pancreatic Cancer Risk

WEDNESDAY, April 15, 2015 (HealthDay News) -- Statin use is inversely associated with pancreatic cancer risk, with evidence of a sex-specific risk reduction, according to a study published in the April 15 issue of Cancer.

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Survey Looks at Patient Attitudes Regarding Informed Consent

WEDNESDAY, April 15, 2015 (HealthDay News) -- Most U.S. adults would prefer to be asked for permission to participate in studies assessing usual medical practices, according to a study published online April 14 in the Annals of Internal Medicine.

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Nanotechnology Breath Test Could Help ID Gastric CA Earlier

TUESDAY, April 14, 2015 (HealthDay News) -- A novel technology senses small changes in the levels of particular compounds in exhaled breath, and accurately identifies changes that signal the development of gastric cancer, according to a study published online April 13 in Gut.

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Security Breaches of Health Records Up Over Past Decade

TUESDAY, April 14, 2015 (HealthDay News) -- Breaches in data security exposed more than 29 million health records to potential criminal misuse between 2010 and 2013, according to a new study. Security breaches involving hacking have nearly doubled in recent years, rising to 8.7 percent in 2013 compared with 4.7 percent in 2010, according to the study, published as a research letter in the April 14 issue of the Journal of the American Medical Association.

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Placebo Response May Depend on Individual DNA

TUESDAY, April 14, 2015 (HealthDay News) -- The strength of the placebo effect may depend on particular DNA, according to a report published online April 13 in Trends in Molecular Medicine.

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Peritoneal Drainage, Laparotomy Cuts Mortality in NEC

MONDAY, April 13, 2015 (HealthDay News) -- For infants with necrotizing enterocolitis (NEC), peritoneal drainage followed by laparotomy is associated with reduced mortality but increased costs compared with peritoneal drainage alone, according to a study published online April 13 in Pediatrics.

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Many Doctors Haven't Started Dealing With ICD-10 Revision

FRIDAY, April 10, 2015 (HealthDay News) -- Most physicians have barely begun to deal with issues relating to documentation associated with the transition to the International Classification of Diseases, 10th Revision (ICD-10), according to an article published in Medical Economics.

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Medical Debt Burden Higher in Texas, Florida

FRIDAY, April 10, 2015 (HealthDay News) -- Significantly more adults in Florida and Texas struggle to pay medical bills or pay off medical debt over time compared with residents of New York and California, according to a new Commonwealth Fund report released Friday.

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Art Program Hones Med Students' Visual Observation Skills

FRIDAY, April 10, 2015 (HealthDay News) -- An innovative interdisciplinary program, Art Rounds, is effective for improving medical and nursing students' physical observation skills, according to a study published in the April issue of the Journal of Nursing Education.

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Statin Use Found Beneficial in Hepatitis C Treatment

FRIDAY, April 10, 2015 (HealthDay News) -- For patients with hepatitis C virus (HCV), statin therapy is associated with improved virologic response rates, as well as decreased liver fibrosis progression and hepatocellular carcinoma (HCC) incidence, according to a study published online April 6 in Hepatology.

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Exercise Dose, Intensity Don't Impact Reduction in Liver Fat

FRIDAY, April 10, 2015 (HealthDay News) -- Reductions in liver fat or visceral adipose tissue (VAT) do not differ significantly with the dose or intensity of aerobic exercise, according to a study published online April 8 in the Journal of Hepatology.

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Two New Strategies Show Promise in Treating Crohn's Dz

FRIDAY, April 10, 2015 (HealthDay News) -- Two experimental therapies show promise in management of Crohn's disease.

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Pharmacists Raise Concerns for Patient Access to Generic Drugs

THURSDAY, April 9, 2015 (HealthDay News) -- Nearly all pharmacists have experienced upswings in the acquisition costs of generic drugs, with price spikes reported to be worse since 2013, according to a report published by the National Community Pharmacists Association (NCPA).

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Inexpensive Antihistamine Repurposed to Focus on HCV

THURSDAY, April 9, 2015 (HealthDay News) -- Preliminary lab research suggests the antihistamine chlorcyclizine HCl that costs about 50 cents a pill has the potential to treat hepatitis C, offering an alternative to the newer medications that can sell for $1,000 a dose. The study appears in the April 8 issue of Science Translational Medicine.

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MRI Could Be Useful Pancreatic Cancer Screen for High-Risk

WEDNESDAY, April 8, 2015 (HealthDay News) -- Using magnetic resonance imaging (MRI) to screen people at high genetic risk for pancreatic cancer might help spot tumors early, according to new research. The findings were published online April 8 in JAMA Surgery.

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Model Predicts Cardiac Death After Life Support Withdrawal

WEDNESDAY, April 8, 2015 (HealthDay News) -- A new model accurately identifies potential organ donors following cardiac death in neurocritical patients removed from life support. The findings were published online March 21 in the American Journal of Transplantation.

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Limited Time Available to Review Sunshine Act Data

WEDNESDAY, April 8, 2015 (HealthDay News) -- Physicians have only 45 days to review and dispute reports regarding their financial ties to drug and medical device manufacturers reported under the Physician Payments Sunshine Act, according to the American Medical Association (AMA).

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Med Students, Residents Rarely Perform Stethoscope Hygiene

TUESDAY, April 7, 2015 (HealthDay News) -- Stethoscope hygiene is rarely performed by trainee physicians, according to a research letter published online April 2 in the Journal of Hospital Medicine.

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FDA Approves New Test That Helps Diagnose Gastroparesis

MONDAY, April 6, 2015 (HealthDay News) -- A new breath test (the Gastric Emptying Breath Test [GEBT]) has been approved by the U.S. Food and Drug Administration to aid in the diagnosis of gastroparesis.

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Half of Colorectal Cancer Survivors Have Continued Pain

MONDAY, April 6, 2015 (HealthDay News) -- Almost half of colorectal cancer (CRC) survivors with pain interference (PI) during the initial phase of care have continued PI post-treatment, according to a study published online March 20 in Pain Medicine.

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Article Highlights Legal Issues Linked to Physician Extenders

FRIDAY, April 3, 2015 (HealthDay News) -- The use of physician extenders (PEs; mainly physician assistants and nurse practitioners) may bring added legal risks to a practice, according to an article published in Medical Economics.

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CDC: Multidrug-Resistant Shigellosis Spreading in U.S.

THURSDAY, April 2, 2015 (HealthDay News) -- Travelers are bringing a drug-resistant strain of the Shigella sonnei bacteria to the United States and spreading it to other people, federal health officials warned Thursday. The report is published in the April 3 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Women Overweight in Youth May Face Higher CRC Risk

THURSDAY, April 2, 2015 (HealthDay News) -- Women who were overweight as children and teens may have a greater risk of colorectal cancer (CRC), no matter what their current weight, a new study cautions. The findings were published in the April issue of Cancer Epidemiology, Biomarkers & Prevention.

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Laparoscopic Sx Achieves Similar Survival Rates in Rectal Cancer

THURSDAY, April 2, 2015 (HealthDay News) -- Patients with localized rectal cancer may achieve similar survival rates by having minimally invasive laparoscopic surgery, instead of more invasive open surgery, according to new research published in the April 2 issue of the New England Journal of Medicine.

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Patients May Be Modifying Meds Due to Trouble Swallowing

THURSDAY, April 2, 2015 (HealthDay News) -- Some patients experience difficulties swallowing and modify medication dosage forms, without necessarily consulting health professionals, according to research published in the March issue of the Journal of Pharmacy Practice and Research.

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Legal Issues of Removing Patient From Practice Explored

WEDNESDAY, April 1, 2015 (HealthDay News) -- The legal and ethical responsibilities of removing a patient from practice are discussed in an article published March 16 in Medical Economics.

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Plasma B12 Levels Tied to Anorexia Nervosa Severity

WEDNESDAY, April 1, 2015 (HealthDay News) -- In patients with anorexia nervosa, plasma levels of vitamin B12 might be an early marker of liver dysfunction and are possibly related to more severe psychopathological aspects, according to a study published in the April issue of the International Journal of Eating Disorders.

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Metformin Use Associated With Less CRC Risk in U.S. Population

WEDNESDAY, April 1, 2015 (HealthDay News) -- For patients with diabetes in the United States, metformin use is associated with reduced risk of developing colorectal cancer (CRC), according to a study published in the April 1 issue of Cancer.

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