Antimicrobial Rx Up With Hospitalization for Acute Mania

This article originally appeared here.
Share this content:
Antimicrobial Rx Up With Hospitalization for Acute Mania
Antimicrobial Rx Up With Hospitalization for Acute Mania

MONDAY, July 25, 2016 (HealthDay News) -- Individuals hospitalized with acute mania have an increased rate of bacterial infections, as evidenced by the recent prescription of antimicrobial agents, according to a study published online July 17 in Bipolar Disorders.

Robert Yolken, M.D., from the Johns Hopkins School of Medicine in Baltimore, and colleagues examined recent prescriptions of systemic antimicrobial medications in 234 individuals hospitalized for acute mania. They also examined 368 individuals hospitalized for other psychiatric disorders and 555 controls.

The researchers found that the rate of recent antimicrobial prescription, defined as exposure within three days of ascertainment, was increased for individuals hospitalized with acute mania (adjusted odds ratio, 5.5; P < 0.0002). Overall, 7.7 percent of individuals hospitalized for acute mania were prescribed antibiotics compared with 1.3 percent of controls. Antibiotic prescription correlated with being on an inpatient unit versus being in the day hospital, and having increased mania symptom severity; there was no association for other clinical ratings, demographic variables, or psychiatric medications. There was no correlation seen for hospitalization for other psychiatric disorders with recent prescription of antimicrobial medications. The most common site of infection in women was the urinary tract, while for men the most common sites were the respiratory tract and mucosal surfaces.

"The prevention and effective treatment of bacterial infections may be important interventions for the management of individuals with mania," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

USPSTF Urges Abuse Screening for Reproductive-Aged Women

USPSTF Urges Abuse Screening for Reproductive-Aged Women

Evidence lacking for assessing balance of benefits, harms of screening for abuse of seniors, vulnerable

Five-Day Nitrofurantoin Beats Single-Dose Fosfomycin for UTI

Five-Day Nitrofurantoin Beats Single-Dose Fosfomycin for UTI

Increased likelihood of clinical and microbiological resolution for uncomplicated UTI in women

Exercise Intervention Doesn't Improve Walking Ability in PAD

Exercise Intervention Doesn't Improve Walking Ability in PAD

Smaller mean change from baseline to follow-up in 6-minute walking distance with exercise intervention

is free, fast, and customized just for you!

Already a member?

Sign In Now »