Antimicrobial Resistance to Carbapenems Increasing

This article originally appeared here.
Share this content:
Antimicrobial Resistance to Carbapenems Increasing
Antimicrobial Resistance to Carbapenems Increasing

TUESDAY, Aug. 16, 2016 (HealthDay News) -- Antimicrobial resistance to carbapenems has increased, and consumption of antibiotics, especially carbapenems, is associated with antimicrobial resistance of Pseudomonas aeruginosa, according to a study published online Aug. 11 in the Journal of Clinical Pharmacy and Therapeutics.

Snezana Mladenovic-Antic, from the University of Nis in Serbia, and colleagues examined the correlation between antimicrobial usage and bacterial resistance of P. aeruginosa over a 10-year period. Antibiotic utilization was recorded, expressed as defined daily doses per 100 bed days.

The researchers identified a significant increasing trend in imipenem and meropenem resistance (both P < 0.05). There was a significant correlation between aminoglycoside consumption and amikacin and gentamicin resistance (both P < 0.01). The correlation between carbapenem consumption and resistance to imipenem in P. aeruginosa was significant (P < 0.01), while there was a trend toward resistance to meropenem (P > 0.05). The correlation between use of all beta-lactam and P. aeruginosa resistance to carbapenems was very good (P < 0.01 for imipenem and P < 0.05 for meropenem).

"Our data demonstrated a significant increase in antimicrobial resistance to carbapenems, significant correlations between the consumption of antibiotics, especially carbapenems and beta-lactams, and rates of antimicrobial resistance of P. aeruginosa to imipenem and meropenem," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Belimumab Aids Anti-dsDNA, Hypocomplementemic Lupus

Belimumab Aids Anti-dsDNA&#43;, Hypocomplementemic Lupus

More SLE Responder Index responders at week 52 in the belimumab group versus the placebo group

Too Few Adults Taking Epilepsy Meds Have Seizure Control

Too Few Adults Taking Epilepsy Meds Have Seizure ...

Ninety percent of those with active epilepsy take meds; 44 percent of those report seizure control

Pediatric Exposures to Liquid Nicotine Down From 2015 to 2016

Pediatric Exposures to Liquid Nicotine Down From 2015 ...

Still poses serious risk to children; decrease likely in part to law requiring child-resistant packaging

is free, fast, and customized just for you!

Already a member?

Sign In Now »