Antidepressant + NSAID May Raise Risk of Intracranial Hemorrhage

Share this content:
Antidepressant+NSAID May Raise Risk of Intracranial Hemorrhage
Antidepressant+NSAID May Raise Risk of Intracranial Hemorrhage

(HealthDay News) -- Of more than four million people prescribed a first-time antidepressant, those who also used nonsteroidal anti-inflammatory drugs (NSAIDs) had a higher risk of intracranial hemorrhage within the next month. The findings were published online July 14 in The BMJ.

Byung-Joo Park, M.D., Ph.D., M.P.H., a professor of preventive medicine at the Seoul National University College of Medicine in South Korea, and colleagues looked at whether the two drug types, used together, might increase the risk of intracranial hemorrhage. The investigators used records from Korea's national health insurance program to find more than four million people given a new prescription for an antidepressant between 2009 and 2013. Half were also using an NSAID.

Park's team found that NSAID users were 60 percent more likely to suffer an intracranial hemorrhage within 30 days of starting their antidepressant -- even with age and chronic medical conditions taken into account. There was no indication that any particular type of antidepressant carried a greater risk than others, Park told HealthDay.

Park agreed that antidepressant users should consult their doctor before taking NSAIDs on their own. Park also pointed out that the study looked at the risk of intracranial hemorrhage within 30 days. So the findings may not apply to people who've been using an antidepressant and NSAID for a longer period with no problem.

Full Text
Editorial

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Meds for Opioid Use Disorder May Reduce Mortality ...

Minority of opioid overdose survivors receive MOUD; buprenorphine, MMT linked to reduced mortality

Pharmacists Are Well Placed to Improve Adult Vaccination Rates

Pharmacists Are Well Placed to Improve Adult Vaccination ...

Pharmacies can address cost barriers to vaccination by providing vaccines at lower cost

Single Blood Sample Test May Help ID Undiagnosed Diabetes

Single Blood Sample Test May Help ID Undiagnosed ...

Single-sample confirmatory definition associated with high positive predictive value

is free, fast, and customized just for you!




Already a member?

Sign In Now »