Another Study Shows Link Between SSRIs and Birth Defects

Share this content:
Another Study Shows Link Between SSRIs and Birth Defects
Another Study Shows Link Between SSRIs and Birth Defects

THURSDAY, July 9, 2015 (HealthDay News) -- New research provides more evidence of a possible link between selective serotonin reuptake inhibitor (SSRI) antidepressant use early in pregnancy and a small increased risk of birth defects. The study appears online July 8 in The BMJ.

Studies in recent years have differed about the risk, if any, to babies born to women who take SSRIs during pregnancy. The new research examined statistics from 17,952 mothers of infants with birth defects and 9,857 other mothers. The children were born between 1997 and 2009. The researchers focused on SSRI use in the first three months of pregnancy.

The researchers found no connection between the SSRIs and nine birth defects that previously had been linked to them. However, they did link a higher risk of five birth defects to paroxetine and two birth defects to fluoxetine. The defects included conditions involving the heart, brain, skull, and abdominal wall. But the added risk was small, the researchers said.

"A woman's chance of having a child with the heart defect we described is about 10 per 10,000. Our results suggest that if she took paroxetine, that risk could increase to 24 per 10,000," study author Jennita Reefhuis, Ph.D., told HealthDay. Reefhuis is an epidemiologist with the U.S. National Center on Birth Defects and Developmental Disabilities at the U.S. Centers for Disease Control and Prevention.

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists can suggest adjustments for meds taken several times per day, those affected by food intake

AUA: Many Have Unused Opioids After Urologic Procedures

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Over Half of Young Adult Smoke Volume Exposure From Hookahs

Over Half of Young Adult Smoke Volume Exposure ...

Toxicant exposure to tar, carbon monoxide, nicotine lower, but still substantial, compared to cigarettes

is free, fast, and customized just for you!

Already a member?

Sign In Now »