Add-On Ultrasonography Ups Mammogram Sensitivity

This article originally appeared here.
Share this content:
Add-On Ultrasonography Ups Mammogram Sensitivity
Add-On Ultrasonography Ups Mammogram Sensitivity

FRIDAY, Nov. 6, 2015 (HealthDay News) -- For young women aged 40 to 49 years, the addition of ultrasonography to mammography increases sensitivity and the detection rate of early breast cancers, according to a study published online Nov. 4 in The Lancet.

Noriaki Ohuchi, Ph.D., from Tohoku University in Sendai, Japan, and colleagues examined the efficacy of adjuvant ultrasonography in asymptomatic women aged 40 to 49 years enrolled at 42 study sites in Japan. Participants with no history of any cancer in the previous five years were randomized to mammography and ultrasound (36,859 women) or mammography alone (36,139 women) twice in two years.

The researchers found that, compared with the control group, the intervention group had significantly higher sensitivity (91.1 versus 77.0 percent; P = 0.0004) and lower specificity (87.7 versus 91.4 percent; P < 0.0001). Compared with the control group, more cancers were detected in the intervention group (0.50 versus 0.32 percent; P = 0.0003) and they were more often stage 0 and I (71.3 versus 52.0 percent; P = 0.0194). Compared with the control group, fewer interval cancers were detected in the intervention group (0.05 versus 0.1 percent; P = 0.034).

"Adjunctive ultrasonography increases sensitivity and detection rate of early cancers," the authors write.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Dupilumab Reduces Rate of Severe Asthma Exacerbations

Dupilumab Reduces Rate of Severe Asthma Exacerbations

And, add-on dupilumab reduces glucocorticoid dose in patients with glucocorticoid-treated asthma

Better Social Support Network Protects Black Men Against HIV

Better Social Support Network Protects Black Men Against ...

Social networks of black men who have sex with men influence HIV risk behavior

Recommendations Developed for Managing Postpartum Pain

Recommendations Developed for Managing Postpartum Pain

Impact of medications on mother-infant dyad should be considered, as many women breastfeed

is free, fast, and customized just for you!

Already a member?

Sign In Now »