Abnormal Chest Radiograph in Active Uveitis Often Sarcoidosis

This article originally appeared here.
Share this content:
Abnormal Chest Radiograph in Active Uveitis Often Sarcoidosis
Abnormal Chest Radiograph in Active Uveitis Often Sarcoidosis

WEDNESDAY, June 7, 2017 (HealthDay News) -- Most patients with active uveitis of unknown origin with abnormal chest radiographs have findings consistent with sarcoidosis, according to a study published in the June 1 issue of the Annals of the American Thoracic Society.

Fahriye Groen, M.D., from the Erasmus Medical Center in Rotterdam, Netherlands, and colleagues conducted a retrospective cross-sectional study by reviewing all chest imaging for adults with new-onset uveitis of unknown origin. The authors related radiographic findings to clinical and other imaging characteristics.

The researchers found that 15 percent of the 200 patients included in the study had abnormal screening chest radiographs. Twenty-two patients (11 percent) had biopsy-confirmed sarcoidosis; 12 additional patients were presumed to have sarcoidosis. For biopsy-confirmed sarcoidosis, the finding of chest radiographic abnormalities interpreted as typical of sarcoidosis was specific, but not sensitive (91 and 64 percent, respectively). The sensitivity was increased to 79 percent with the combination of elevated serum angiotensin-converting enzyme level and chest radiographic findings typical of sarcoidosis. Patients with panuveitis more often had biopsy-confirmed sarcoidosis than those with other anatomical locations of uveitis (20 versus 4 percent).

"Our study shows that an abnormal chest radiograph was observed for 15 percent of 200 patients with active uveitis of unknown origin and of less than one year in duration," the authors write.

The study was partially funded by AbbVie.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Mortality Estimates Favor Annual Mammography From Age 40

Mortality Estimates Favor Annual Mammography From Age 40

Researchers estimate thousands of U.S. lives would be saved each year if mammograms started at age 40

Anti-Vaccine Info in Pregnancy May Delay Infant Immunization

Anti-Vaccine Info in Pregnancy May Delay Infant Immunization

Even if pregnant women later hear better info from doctors, they may still wait on vaccines

Hours Worked Impacted by Kids for Female, Not Male Doctors

Hours Worked Impacted by Kids for Female, Not ...

Findings from a national sample of dual-physician couples

is free, fast, and customized just for you!

Already a member?

Sign In Now »