Case Clinics



SGLT2 Inhibitors in Type 2 Diabetes: Incorporating New Approaches Into Practice Through an Interdisciplinary Exploration

The sodium-glucose cotransporter 2 (SGLT2) inhibitors, the newest drug class in the type 2 diabetes mellitus (T2DM) treatment arsenal, target renal glucose reabsorption as a means of reducing hyperglycemia. Three agents in this class, canagliflozin, dapagliflozin, and empagliflozin, are approved to treat T2DM in the United States, as are fixed-dose combinations of some SGLT2 inhibitors with metformin or a DPP-4 inhibitor. To leverage the potential benefits of these agents and improve patient outcomes, clinicians need to be aware of the most recent data on the SGLT2 inhibitors and when and how to incorporate them into T2DM management plans. In the 2 Clinical Consult video activities below, faculty discuss how to apply this information to specific patient cases.


Each activity offers:
Clinical Consult Case 1: 0.50 AMA PRA Category 1 CreditTM
Clinical Consult Case 2: 0.50 AMA PRA Category 1 CreditTM

Adopting a Patient-Centered Approach in the Management of COPD to Improve the Continuum of Care

Treatment of acute exacerbations of chronic obstructive pulmonary disease (COPD) remains the major factor in increasing healthcare costs associated with COPD. Patients who survive severe exacerbations of COPD are at higher risk of hospital readmission and death. The challenges of assessment of COPD and exacerbation severity are compounded by nonadherence or inadequate medical management. In the Specialty House Call cases below, faculty discuss how to address persistent dyspnea, prevent exacerbations, avert rehospitalizations, and reduce associated healthcare costs.


Each activity offers:
Specialty House Calls Case 1: 0.50 AMA PRA Category 1 CreditTM
Specialty House Calls Case 2: 0.50 AMA PRA Category 1 CreditTM

Achieving Sustained Remission in Major Depressive Disorder: Patient-Centered Strategies for Improved Outcomes

New multimodal antidepressants appear to be particularly efficacious in targeting the residual symptoms of MDD, particularly in regard to cognitive deficits, with favorable side-effect profiles. However, clinicians are often unsure how to best utilize these agents, and which patients are the most appropriate candidates for these therapies. Many patients remain on an initial dosage of antidepressant medication for many months, despite having persistent and often debilitating depressive symptoms. Patient/provider communication in MDD treatment is frequently subpar, and a large proportion of patients report dissatisfaction with their current treatment regimen.

Each case offers:
Clinical Case 1: 0.50 AAPA Category 1 CME Credits and 0.50 CE for Nurses
Clinical Case 2: 0.50 AAPA Category 1 CME Credits and 0.50 CE for Nurses
Clinical Case 3: 0.50 AAPA Category 1 CME Credits and 0.50 CE for Nurses

A Tale of Three Patients: Contrasting Approaches in the Diagnosis and Management of OAB

This three-part educational series focuses on the diagnosis and management of OAB through interactive discussions between the patient and physician. OAB is a symptom complex commonly encountered in clinical practice and requires tailored management strategies based on symptom severity, degree of bother, and patients' ability and willingness to adhere to treatment.

Each activity worth:
Module 1 offers 1.00 AMA PRA Category 1 CME CreditTM / 1.00 CE for Nurses.
Module 2 offers 0.50 AMA PRA Category 1 CME CreditsTM / 0.50 CE for Nurses.
Module 3 offers 0.25 AMA PRA Category 1 CME CreditsTM / 0.25 CE for Nurses. (To Come)

Clinical Conversations in Epilepsy: Optimizing Therapeutic Options for Partial-Onset Seizures

Epilepsy, a chronic neurological condition, is characterized by recurrent seizures that occur due to abnormal electrical activity in the brain. This integrated series of online educational activities allows for sequential learning, providing multiple, linked educational opportunities that reinforce learning and accommodate a variety of learning styles and preferences. In addition, each component in the program can be used to encourage participation in the others. The information in these cases will be practical and patient-focused to enable learners to make confident clinical decisions for their patients with epilepsy.

Each activity worth:
Case 1 and 2 offer 0.75 AMA PRA Category 1 CME Credit(s)TM.
The monograph offers 1.00 AMA PRA Category 1 CME Credit(s)TM.

Maintaining the Continuum of Care in Patients With COPD From Hospital to Home

This case series features a 58-year-old woman who presents to the hospital with severe breathing problems at the height of flu season, and is diagnosed and treated for AECOPD. Case 1 underlines best practices for assessing and managing AECOPD, including appropriate treatment and preventive strategies. Case 2 follows the patient at discharge, and explores the new CMS rules and penalties for COPD readmissions, patient risk factors contributing to readmissions, and best practices for transitioning COPD patients from hospital to home that may help mitigate readmission.

Each activity worth:
1.00 / AMA PRA Category 1 CreditsTM

Long-acting and Permanent Contraception: Helping Patients Make the Choice

Choosing to put an end to fertility is a critical and highly personal decision. Unfortunately, evidence indicates that many women make such a decision without adequate information about all their options and the benefits and risks associated with each. These may include long-acting reversible contraceptive methods such as intrauterine devices and contraceptive implants, with efficacy comparable to sterilization, and minimally invasive approaches to tubal sterilization. To ensure that women make individually appropriate decisions, clinicians should both educate patients about their options and adopt a shared decision-making model in which physicians and other health care providers collaborate with patients whenever feasible.

Each activity worth:
0.50 / AMA PRA Category 1 CreditsTM

Alzheimer's Disease and Dementia Case Clinic

This educational series seeks to address the clinical challenges in diagnosing dementia and Alzheimer's disease. The case clinic series will focus on discussion of various subtypes of dementia; physical, neuroimaging, and neuropsychological assessments; and the incorporation of biomarker measurements in the clinical setting.


Each activity worth:
Case 1 offers 1.00 AMA PRA Category 1 CME Credit(s)TM
Case 2 and Case 3 offer 0.50 AMA PRA Category 1 CME Credit(s)TM

Idiopathic Pulmonary Fibrosis Case Clinic

Clinicians who diagnose, treat, and manage patients with idiopathic pulmonary fibrosis (IPF) should be at the forefront of understanding new diagnostic and management guidelines in addition to treatment options. With the recent approval of promising agents for IPF, options are available to decelerate progression of this end-stage fibrotic lung disease, which can greatly impact clinical practice. This series consists of 2 Clinical Case Studies designed as digital flipbooks, an easy-to-follow, page-turning format that is engaging and offers the ability to navigate content at one's own pace.


Each activity worth:
1.00 / AMA PRA Category 1 CreditsTM

Basal Insulin and GLP-1 RAs Case Clinic

Individual glycemic patterns (a key, but often overlooked, element of diabetes treatment design) can help clinicians determine which patients are candidates for treatment with a basal insulin, a GLP-1 receptor agonist, or both. This activity also addresses elements of clinical inertia and how clinicians can help patients overcome trepidation about needle-delivered medications.

Each activity worth:
1.00 / AMA PRA Category 1 CME Credit(s)TM

Systemic Lupus Erythematosus Case Clinic

Updates in the management of lupus nephritis over the past 2 decades have translated into improved renal and patient survival rates. Different immunosuppressive treatment options are now available that may facilitate individualization of treatment to optimize the outcomes, especially when considering patients with various ethnic backgrounds and women of childbearing age.

Each activity worth:
1.00 / AMA PRA Category 1 CME Credit(s)TM

Schizophrenia: Long-Acting Injectable Medications Case Clinic

Adherence to antipsychotic medication is crucial for minimizing the symptoms of schizophrenia and maximizing the patient's function in society. Long-acting injectable antipsychotic drugs can be integral in assisting certain patients in managing their illness, even those with first-episode schizophrenia.

Each activity worth:
0.50 / AMA PRA Category 1 CME Credit(s)TM

Schizophrenia: Managing Acute Agitation Case Clinic

This case clinic series will focus on strategies to effectively diagnose agitation among patients with schizophrenia and bipolar disorder, and assess standard and emerging pharmacologic agents (including pharmacokinetic/pharmacodynamic properties) that foster rapid onset to manage agitation.

Each activity worth:
0.50 / AMA PRA Category 1 CME Credit(s)TM

Gastric Cancer Case Clinic

There is a critical educational need among clinicians involved in the care and management of African American, Asian American and Hispanic American patients with gastric cancer.


Each activity worth:
0.75 / AMA PRA Category 1 CME Credit(s)TM

Alzheimer's Case Clinic

Contemporary understanding of Alzheimer's disease (AD) has evolved, so that it is now recognized as representing a continuum from a preclinical stage to mild cognitive impairment and finally to dementia. Similarly, diagnosis is evolving, sometimes requiring an array of assessments from a simple medical history to advanced imaging technologies and the use of biomarkers.

Each activity worth:
0.50 / AMA PRA Category 1 Credit(s)TM

Hepatitis C Case Clinic

This series of interrelated patient case studies will focus on HCV diagnosis and comanagement with specialty care over the long term, with a discussion of the most recent efficacy, safety, and resistance data for new and emerging HCV agents, and the implications of these developments for clinical practice.

Activities no longer available for credit

Influenza Vaccination Case Clinic

Updating pediatric clinicians about influenza and its impact, current options and recommendations for influenza immunization, and strategies for effective parent counseling/education about influenza vaccination can aid them in effective decision-making, help them improve immunization rates, and continue the efforts toward eliminating vaccine-preventable diseases.

Activities no longer available for credit

Culture and Pathophysiology in T2DM Treatment Case Clinic

In this case series, we meet one patient at three points in her diabetes management history, and learn how her African American ethnicity affects her perceptions and attitudes about diabetes self-management.

Activities no longer available for credit

Pediatric Nutrition Case Clinic

Adequate nutrition early in life can have long-term health effects, particularly in the prevention of pediatric allergy, in how choice of infant nutrition can affect the growth of gut microflora and infant health, and the benefits of breastfeeding. Pediatricians need to be aware of the most current strategies for optimal infant nutrition as well as strategies for parent education.

Activities no longer available for credit

Allergic Rhinitis Case Clinic

For the many patients who self-treat their symptoms with over-the-counter medications, pharmacists ideally can provide appropriate counseling and identify those who could benefit from specialist care. Providing information about treatment options and medication administration techniques can improve patient satisfaction, adherence, and outcomes.

Activities no longer available for credit

Non-Small Cell Lung Cancer Case Clinic

Studies have shown that African-American patients with NSCLC are less likely to receive timely treatment and have poorer outcomes. This case clinic is designed to provide guidance on how to overcome these disparities and help learners identify the specific molecular biomarkers and appropriate treatment standards that can lead to optimal response rates in African-American populations with NSCLC.

Activities no longer available for credit

HIV Case Series

Focused on a recently diagnosed young African-American man with HIV, this primary-care set case study will explore barriers to HIV screening among minority patients as well as some of the barriers that contribute to poor outcomes in HIV-infected African Americans.

Activities no longer available for credit

An Update on Schizophrenia Management

It is estimated that up to 27% of patients with schizophrenia display negative symptoms that persist for 6 months after initial stabilization following a first psychotic episode. Such symptoms account for much of the long-term morbidity and poor outcomes seen in patients with this condition. Antipsychotic medications can ameliorate or greatly improve the positive symptoms of schizophrenia; unfortunately, these agents typically show little effect on either primary or persistent negative symptoms.

Each activity worth:
0.50 / AMA PRA Category 1 Credit(s)TM

Major Depressive Disorder Case Clinic

Because major depressive disorder (MDD) is a complex and heterogeneous disease, treatment requires a highly individualized yet systematic approach. In this case, a patient with MDD and comorbid anxiety expresses concern about the potential for adverse effects of treatment.

Activities no longer available for credit

Chronic Pain Case Clinic

By definition, chronic pain burdens patients, impairing their ability to work and carry out other activities of daily life, hampering sleep, exacerbating concomitant illness, and generally diminishing quality of life. For clinicians, managing long-term pain can be tremendously frustrating, and the subjective nature of pain perception means that even assessing response to treatment can be difficult.

Activities no longer available for credit

T2DM Case Clinic

This three-part case clinic series, "Enhancing Glycemic Control in Type 2 Diabetes: Achieving Standards of Care in Primary Care," presents common, real-world problems in diabetes management and how to respond to them.

Activities no longer available for credit

Lipid Case Clinic

These activities, through varied modalities and non-educational interventions, will cover multiple key topics crucial to improving the knowledge-base of PCPs, including: the significance of dyslipidemia in the context of the cardiometabolic syndrome and lipid metabolism; and diagnostic criteria for dyslipidemia.

Activities no longer available for credit

RSV Infection in Infants: Implementing Optimal Strategies

Respiratory syncytial virus (RSV) can result in an infection that can be severe and life-threatening in high-risk infants. Pediatric clinicians who are up-to-date about risk factors, current recommendations for prevention and management of RSV infection, and strategies for parent counseling can aid parents in effective decision making and help improve outcomes in their pediatric patients.

Activities no longer available for credit

First Steps on the Road to Good Health: An Infant Nutrition Update

This series of 3 clinical case studies will explore many of the nutritional issues that clinicians who manage the care of infants are likely to encounter in practice. The activity will prepare participants to more effectively counsel parents on the latest recommendations and evidence-based data on optimal infant feeding and to help set the stage for positive health throughout each child's life span.

Activities no longer available for credit

Oncology Case Clinic

These patient case study courses are designed for oncologists, thoracic surgeons, pathologists, internists, ob/gyns, and other clinicians who treat or manage women with breast cancer.


Activities no longer available for credit

Major Depressive Disorder: Assessing and Addressing Residual Symptoms

MDD is a common mental health problem; most patients with the condition are treated in primary care settings. Primary care clinicians can provide effective education to ensure that patients understand depression and its treatments. These clinicians are also in a position to implement measurement-based assessment and monitoring of patients using antidepressant therapy.

Activities no longer available for credit

Dialogues on Diabetes and Dyslipidemia

Many individuals with type 2 diabetes mellitus (T2DM) are overweight and have an increased prevalence of dyslipidemia, which significantly increases their risk for cardiovascular disease. The cases in this series illustrate the challenges of managing patients with both T2DM and dyslipidemia.

Activities no longer available for credit

Optimizing Influenza Immunization Rates in Pediatric Patients

When children are due for influenza and other immunizations, the clinician needs to address parental concerns about safety as well as the child's issues in order to optimize influenza immunization rates.

Activities no longer available for credit

Stroke Prevention in Atrial Fibrillation: Strategies for Optimal Anticoagulation

In patients with atrial fibrillation (AF), the risk of stroke continues to be under-recognized and anticoagulation underused, with many missed opportunities for preventing strokes. Risk stratification tools help evaluate the risk for stroke and bleeding, and newer anticoagulants may increase prophylaxis and improve adherence. Strategies for optimal stroke prevention, risk stratification, and patient education can enhance outcomes in patients with AF at risk for stroke.

Activities no longer available for credit

Optimizing PPI Therapy for GERD: Evidence-based Guidance for Improved Safety and Efficacy

Proton pump inhibitors (PPIs) have become the gold-standard for the treatment of gastroesophageal reflux disease (GERD), as well as for the prevention of GERD-related complications. In recent years, these agents have been linked with serious adverse events and possible drug interactions. This CME/CE program will present 3 detailed patient scenarios to illustrate how PPIs can be used to their best effect in a variety of populations, while minimizing the risk for treatment-related adverse events.

Activities no longer available for credit

Improving Quality of Life for Patients With Shift Work Disorder

These cases, as well as the Tool/Care Kit, feature information about strategies for identifying, diagnosing, and managing patients with shift work disorder and improving patient quality of life.

Activities no longer available for credit

Pediatric Nutrition and Long-Term Health: Exploring the Critical Link

While the American Academy of Pediatrics strongly recommends that all infants be breast-fed until they are at least 12 months old, the majority receive formula by the age of 6 months. This series will explore the most recent recommendations and evidence-based data on the available nutritional options for these infants.

Activities no longer available for credit

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