Zika Virus Can Cause Retinal Damage in Infants

Share this content:
Zika Virus Can Cause Retinal Damage in Infants
Zika Virus Can Cause Retinal Damage in Infants

FRIDAY, Nov. 11, 2016 (HealthDay News) -- For infants with congenital Zika syndrome (CZS), Zika virus (ZIKV) can cause retinal damage, which can be seen on optical coherence tomography (OCT), according to a study published online Nov. 10 in JAMA Ophthalmology.

Camila V. Ventura, M.D., from Altino Ventura Foundation in Recife, Brazil, and colleagues conducted a cross-sectional consecutive case series involving eight infants with CZS. OCT images were obtained in the affected eyes of the infants. An immunoglobulin M (IgM) antibody-capture enzyme-linked immunosorbent assay was performed for ZIKV on the cerebrospinal fluid of seven of the infants.

The researchers found that the seven infants who underwent cerebrospinal fluid analysis for ZIKV had positive findings for IgM antibodies. Eleven of the 16 eyes of the eight infants had retinal alterations; OCT imaging was performed in nine of these eyes, and in one unaffected eye. In the affected eyes, the main OCT findings included discontinuation of the ellipsoid zone and hyperreflectivity underlying the retinal pigment epithelium (nine eyes); retinal thinning (eight eyes); choroidal thinning (seven eyes); and colobomatous-like excavation involving the neurosensory retina, retinal pigment epithelium, and choroid (four eyes).

"Zika virus can cause severe damage to the retina, including the internal and external layers, and the choroid," the authors write. "The colobomatous-like finding seen in the OCT images relate to the excavated chorioretinal scar observed clinically."

Full Text
Editorial

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Progress Made on Genetic Test for Anal Cancer

Progress Made on Genetic Test for Anal Cancer

But research is still in early stages

Four Separate Events Led to Zika's Introduction Into Florida

Four Separate Events Led to Zika's Introduction Into ...

Virus strains came from the Caribbean and Latin America, researchers say

New Health Care Act Could Result in 23 Million Losing Insurance

New Health Care Act Could Result in 23 ...

While premiums may lower over the long-term, many would face much higher out-of-pocket costs

is free, fast, and customized just for you!

Already a member?

Sign In Now »