Overall Survival in Mantle Cell Lymphoma Up With Deferred Tx

This article originally appeared here.
Share this content:
Overall Survival in Mantle Cell Lymphoma Up With Deferred Tx
Overall Survival in Mantle Cell Lymphoma Up With Deferred Tx

TUESDAY, May 24, 2016 (HealthDay News) -- For patients with mantle cell lymphoma (MCL), deferred therapy seems safe and is an independent predictor of overall survival, according to a study published online May 6 in Cancer.

Jonathon B. Cohen, M.D., from Emory University in Atlanta, and colleagues examined the role of deferred therapy in MCL in a cohort of 8,029 patients. Overall, 6 percent of the patients received deferred therapy (time from diagnosis to treatment >90 days; median time to treatment, 121 days).

The researchers found that patients who deferred therapy were more likely to have stage I or II disease and extranodal involvement; they were also less likely to have B symptoms. The likelihood of being treated at a high-volume teaching/research institution was increased for deferred patients, and they were more likely to reside in the Northeast or West region. For all patients with MCL, deferred therapy was an independent predictor of overall survival. Predictors of improved overall survival among patients who deferred therapy included male sex, younger age, and a lack of comorbidities.

"Deferred therapy is a safe option for a subset of patients with MCL," the authors write. "Further study is required to better identify the best candidates for deferred therapy according to baseline risk stratification in MCL."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

SAMHSA: Youth Binge Drinking Rates Down in the United States

SAMHSA: Youth Binge Drinking Rates Down in the ...

But one in seven still consumed excess alcohol at least once in past month, study finds

Carpal Tunnel Up With Increased Electronic Device Use

Carpal Tunnel Up With Increased Electronic Device Use

Especially for those who spend more than five hours a day on their devices, researchers say

Guided Approach to Exercise May Help Chronic Fatigue Patients

Guided Approach to Exercise May Help Chronic Fatigue ...

Guided self-help approach to graded exercise program safe, reduces fatigue

is free, fast, and customized just for you!

Already a member?

Sign In Now »